Expression and Significance of Vascular Endothelial Growth Factor Receptors 2 and 3 in Endometrial Carcinoma

Noor E. AL-Attar; Abeer A. Al–Hadidy

doi:10.54172/

Article Details

Expression and Significance of Vascular Endothelial Growth Factor Receptors 2 and 3 in Endometrial Carcinoma

Authors:

Noor E. AL-Attar | Abeer A. Al–Hadidy

Publisher:

Omar Al-Mukhtar University

Journal:

Al-Mukhtar Journal of Sciences Vol.38 Issue 3, pp.306-317

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001391601

pISSN:

3006-6352

DOI:

10.54172/

Keywords:

Abstract:

 Polycystic ovary syndrome (PCOS) is one of the most widespread endocrine hormone disorders that affects women of reproductive age. It’s a major public health concern that leads to dysregulations in the reproductive, metabolic, and psychological systems. Anovulation, which has a significant impact on female fertility, and hyperandrogenism are the most characteristic of PCOS. Because of its endocrine role, adipose tissue secretes several proteins called adipokines that work as hormones controlling bodily functions, including resistin, betatrophin, etc. The cases involved in this study were 90 women. For comparison, 30 healthy women with regular periods suitable with age were used as a control group. 30 Obese PCOS women were diagnosed depending on the Rotterdam criteria as group2, and 30 non-obese PCOS women as group3. The results showed there was a significant elevate in insulin and insulin resistance and related hormones between groups compared to the control, and a significant increase at (P≤ 0.01) in levels of betatrophin in group2 compared to the control, with a significant difference between the group2 and group3, and a significant increase at (P≤ 0.01) in levels of kisspeptin in group2 compared to the control. No significant difference between group2 and group3 and a significant difference between group3 and the control group.

Article Details

Expression and Significance of Vascular Endothelial Growth Factor Receptors 2 and 3 in Endometrial Carcinoma

Authors:

Noor E. AL-Attar | Abeer A. Al–Hadidy

Publisher:

Omar Al-Mukhtar University

Journal:

Al-Mukhtar Journal of Sciences Vol.38 Issue 3, pp.306-317

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001391601

pISSN:

3006-6352

DOI:

10.54172/

Betatrophin

Kisspeptin

PCOS

Insulin resistance

Issues

Article Details

Expression and Significance of Vascular Endothelial Growth Factor Receptors 2 and 3 in Endometrial Carcinoma

Authors: Noor E. AL-Attar | Abeer A. Al–Hadidy

Publisher: Omar Al-Mukhtar University

Journal: Al-Mukhtar Journal of Sciences Vol.38 Issue 3, pp.306-317

Document Type: Article

Publication Date: 12/2023

Document Language: English

Document ID (Org No.): 2001391601

pISSN: 3006-6352

DOI: 10.54172/

Betatrophin

Kisspeptin

PCOS

Insulin resistance

Issues

Authors:

Noor E. AL-Attar | Abeer A. Al–Hadidy

Publisher:

Omar Al-Mukhtar University

Journal:

Al-Mukhtar Journal of Sciences Vol.38 Issue 3, pp.306-317

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001391601

pISSN:

3006-6352

DOI:

10.54172/