Evaluation of chronic fatigue syndrome, depression, anxiety and somatization disorder individuals with a primary diagnosis of fibromyalgia

Canan Emiroğlu; Nesrin Dilbaz

Article Details

Evaluation of chronic fatigue syndrome, depression, anxiety and somatization disorder individuals with a primary diagnosis of fibromyalgia

Authors:

Canan Emiroğlu | Nesrin Dilbaz

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Klinik Tıp Bilimleri (Diğer)

Journal:

Journal of Health Sciences and Medicine Vol.8 Issue 4, pp.686-691

Document Type:

Article

Publication Date:

7/2025

Document Language:

English

Document ID (Org No.):

2001355829

pISSN:

2636-8579

Keywords:

Abstract:

 Aims: Currently, fibromyalgia FM is still diagnosed solely on clinical grounds, as no serologic, imaging, or histologic markers are available. Chronic fatigue syndrome CFS shares many similarities with FM. The implication of similar etiological factors and mechanisms, the overlap in symptoms and signs, and the high prevalence of psychiatric disorders such as anxiety, depression, panic attacks, and somatization disorder in both conditions have led to suggestions that they may represent different manifestations of the same disease. The primary objective of this investigation was to assess the prevalence of comorbid psychiatric conditions including depression, anxiety, and somatization disorder as well as CFS, among individuals diagnosed with FM, and to explore potential overlaps in their clinical presentation. Methods: In this prospective, cross-sectional study, the prime MD scale was applied to 60 patients diagnosed with FM to investigate their overlap with psychiatric diagnoses. In addition, patients were evaluated according to the Fukuda Classification System to determine whether they could be diagnosed with CFS. Results: The incidence rate of anxiety disorder was 33.3 and the incidence rate of somatoform disorder was 83.4. Major depression was detected in 10 patients 16.7 and dysthymia in 16 patients. Eight out of 60 patients 13.3 did not have any psychiatric disorders, while the remaining 52 patients had at least one disorder or more than one disorder. Although 50 of 60 patients 83.3 complained of fatigue, only 8 13.3 patients were diagnosed by meeting sufficient criteria for CFS. Conclusion: Although FM and CFS are not the same clinical entity, they appear to be two conditions with overlapping symptoms, particularly psychiatric ones, which frequently coexist. The prevalence of psychiatric symptoms and diagnoses was notably higher among individuals who met the diagnostic criteria for both FM and CFS. Further research is needed to refine and evaluate the diagnostic criteria for both conditions.

 Aims: Currently, fibromyalgia FM is still diagnosed solely on clinical grounds, as no serologic, imaging, or histologic markers are available. Chronic fatigue syndrome CFS shares many similarities with FM. The implication of similar etiological factors and mechanisms, the overlap in symptoms and signs, and the high prevalence of psychiatric disorders such as anxiety, depression, panic attacks, and somatization disorder in both conditions have led to suggestions that they may represent different manifestations of the same disease. The primary objective of this investigation was to assess the prevalence of comorbid psychiatric conditions including depression, anxiety, and somatization disorder as well as CFS, among individuals diagnosed with FM, and to explore potential overlaps in their clinical presentation. Methods: In this prospective, cross-sectional study, the prime MD scale was applied to 60 patients diagnosed with FM to investigate their overlap with psychiatric diagnoses. In addition, patients were evaluated according to the Fukuda Classification System to determine whether they could be diagnosed with CFS. Results: The incidence rate of anxiety disorder was 33.3 and the incidence rate of somatoform disorder was 83.4. Major depression was detected in 10 patients 16.7 and dysthymia in 16 patients. Eight out of 60 patients 13.3 did not have any psychiatric disorders, while the remaining 52 patients had at least one disorder or more than one disorder. Although 50 of 60 patients 83.3 complained of fatigue, only 8 13.3 patients were diagnosed by meeting sufficient criteria for CFS. Conclusion: Although FM and CFS are not the same clinical entity, they appear to be two conditions with overlapping symptoms, particularly psychiatric ones, which frequently coexist. The prevalence of psychiatric symptoms and diagnoses was notably higher among individuals who met the diagnostic criteria for both FM and CFS. Further research is needed to refine and evaluate the diagnostic criteria for both conditions.

 Aims: Currently, fibromyalgia FM is still diagnosed solely on clinical grounds, as no serologic, imaging, or histologic markers are available. Chronic fatigue syndrome CFS shares many similarities with FM. The implication of similar etiological factors and mechanisms, the overlap in symptoms and signs, and the high prevalence of psychiatric disorders such as anxiety, depression, panic attacks, and somatization disorder in both conditions have led to suggestions that they may represent different manifestations of the same disease. The primary objective of this investigation was to assess the prevalence of comorbid psychiatric conditions including depression, anxiety, and somatization disorder as well as CFS, among individuals diagnosed with FM, and to explore potential overlaps in their clinical presentation. Methods: In this prospective, cross-sectional study, the prime MD scale was applied to 60 patients diagnosed with FM to investigate their overlap with psychiatric diagnoses. In addition, patients were evaluated according to the Fukuda Classification System to determine whether they could be diagnosed with CFS. Results: The incidence rate of anxiety disorder was 33.3 and the incidence rate of somatoform disorder was 83.4. Major depression was detected in 10 patients 16.7 and dysthymia in 16 patients. Eight out of 60 patients 13.3 did not have any psychiatric disorders, while the remaining 52 patients had at least one disorder or more than one disorder. Although 50 of 60 patients 83.3 complained of fatigue, only 8 13.3 patients were diagnosed by meeting sufficient criteria for CFS. Conclusion: Although FM and CFS are not the same clinical entity, they appear to be two conditions with overlapping symptoms, particularly psychiatric ones, which frequently coexist. The prevalence of psychiatric symptoms and diagnoses was notably higher among individuals who met the diagnostic criteria for both FM and CFS. Further research is needed to refine and evaluate the diagnostic criteria for both conditions.

 Giriş: Kronik yaygın ağrı, dünya genelinde yetişkinlerin 10 ila 15ini etkilemektedir ve bunların çoğunda fibromiyalji FM bulunmaktadır. FM genel popülasyonda oldukça yaygın bir sendromdur ve bel ağrısı ve osteoartritten sonra üçüncü en yaygın kas-iskelet sistemi rahatsızlığıdır. Günümüzde, serolojik, görüntüleme veya histolojik belirteçler mevcut olmadığından, FM tanısı hala sadece klinik olarak konulmaktadır. Kronik Yorgunluk Sendromu birçok açıdan PFSye benzemektedir. Etiyolojilerinde benzer faktör ve mekanizmaların suçlanması, aynı semptom ve bulguların birlikte görülmesi ve her iki hastalıkta da anksiyete, depresyon, panik atak ve somatizasyon bozukluğu gibi psikiyatrik bozuklukların yüksek prevalansı, bu iki durumun aynı hastalığın farklı tezahürleri olabileceği iddialarına yol açmıştır. Amaç: Bu araştırmanın amacı, PFS tanısı almış kişilerde kronik yorgunluk sendromu KYS ile birlikte depresyon, anksiyete ve somatizasyon bozukluğu gibi komorbid psikiyatrik durumların yaygınlığını değerlendirmek ve klinik sunumdaki potansiyel örtüşmeyi incelemektir. Materyal ve metod: Bu prospektif, kesitsel çalışmada, psikiyatrik tanılarla örtüşmelerini araştırmak için PFS tanısı alan 60 hastaya Prime MD ölçeği uygulanmıştır. Ayrıca, hastalar KFS tanısı alıp alamayacaklarını belirlemek için Fukuda Sınıflandırma Sistemine göre değerlendirilmiştir. Bulgular: Anksiyete bozukluğu görülme oranı 33,3 ve somatoform bozukluk görülme oranı 83,4 idi. Majör depresyon 10 hastada 16.7 ve distimi 16 hastada saptandı. 60 hastanın sekizinde 13,3 herhangi bir psikiyatrik bozukluk bulunmazken, geri kalan 52 hastada en az bir veya birden fazla bozukluk vardı. 60 hastanın 50si 83,3 yorgunluktan şikayetçi olmasına rağmen, sadece 8 13,3 hasta KYS için yeterli kriterleri karşılayarak tanı almıştır. Sonuç: PFS ve KYS aynı klinik antite olmamakla birlikte, benzer semptomların örtüştüğü iki klinik durum gibi görünmektedir, özellikle psikiyatrik semptomlar ve durumlar sıklıkla bir arada bulunmaktadır. Psikiyatrik belirti ve tanıların yaygınlığının, özellikle hem PFS hem de KYS tanı kriterlerini karşılayan bireyler arasında yüksek olduğu görülmüştür.

Article Details

Evaluation of chronic fatigue syndrome, depression, anxiety and somatization disorder individuals with a primary diagnosis of fibromyalgia

Authors:

Canan Emiroğlu | Nesrin Dilbaz

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Klinik Tıp Bilimleri (Diğer)

Journal:

Journal of Health Sciences and Medicine Vol.8 Issue 4, pp.686-691

Document Type:

Article

Publication Date:

7/2025

Document Language:

English

Document ID (Org No.):

2001355829

pISSN:

2636-8579

Fibromyalgia

fatigue

depression

anxiety

somatoform disordersfibromiyalji

yorgunluk

depresyon

anksiyete

Issues

Article Details

Authors: Canan Emiroğlu | Nesrin Dilbaz

Publisher: MediHealth Academy Yayıncılık

Main Topics: Klinik Tıp Bilimleri (Diğer)

Journal: Journal of Health Sciences and Medicine Vol.8 Issue 4, pp.686-691

Document Type: Article

Publication Date: 7/2025

Document Language: English

Document ID (Org No.): 2001355829

pISSN: 2636-8579

Issues

Authors:

Canan Emiroğlu | Nesrin Dilbaz

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Klinik Tıp Bilimleri (Diğer)

Journal:

Journal of Health Sciences and Medicine Vol.8 Issue 4, pp.686-691

Document Type:

Article

Publication Date:

7/2025

Document Language:

English

Document ID (Org No.):

2001355829

pISSN:

2636-8579