Coexistence of preeclampsia and inherited thrombophilia in Turkish pregnant women

Mehtap POLAT; Ebru Hacer BİBEROĞLU; İsmail GÜLER; Ömer Kutay BİBEROĞLU

Article Details

Coexistence of preeclampsia and inherited thrombophilia in Turkish pregnant women

Authors:

Mehtap POLAT | Ebru Hacer BİBEROĞLU | İsmail GÜLER | Ömer Kutay BİBEROĞLU

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 4, pp.1094-1100

Document Type:

Article

Publication Date:

7/2016

Document Language:

Turkish

Document ID (Org No.):

2000751946

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Abstract:

 

Background/aim: To examine the relationship of inherited thrombophilia and other thrombotic risk factors with preeclampsia (PE) in a population of pregnant Turkish women.  Materials and methods: This was a case cross-sectional study in which 70 women with PE and 60 normal pregnant women were studied to find out the frequency of women with risk factors including inherited thrombophilia among preeclamptic cases.   Results: Hemoglobin, platelet count, uric acid, vitamin B12, folic acid, copper, homocysteine, plasminogen activator inhibitor-1, fibrinogen, protein S, protein C, activated protein C resistance values show significant differences in women with PE in comparison to women with normal pregnancy.     Conclusion: There may be a link between inherited thrombophilia and PE, at least in a sample of Turkish pregnant women. We also propose that the association between thrombophilia and PE is stronger than suggested previously. Furthermore, copper is selectively elevated in women with PE as an independent marker.

Article Details

Coexistence of preeclampsia and inherited thrombophilia in Turkish pregnant women

Authors: Mehtap POLAT | Ebru Hacer BİBEROĞLU | İsmail GÜLER | Ömer Kutay BİBEROĞLU

Publisher: TUBITAK

Journal: Turkish Journal of Medical Sciences 2016 Vol.46 Issue 4, pp.1094-1100

Document Type: Article

Publication Date: 7/2016

Document Language: Turkish

Document ID (Org No.): 2000751946

Frequency: Bimonthly

eISSN: 1303-6165

pISSN: 1300-0144

Issues

Authors:

Mehtap POLAT | Ebru Hacer BİBEROĞLU | İsmail GÜLER | Ömer Kutay BİBEROĞLU

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 4, pp.1094-1100

Document Type:

Article

Publication Date:

7/2016

Document Language:

Turkish

Document ID (Org No.):

2000751946

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144