Evaluating ESWL related alterations in renal pelvis and proximal ureter by analayting of tissue hydroxyproline levels

Mine ŞENYÜCEL; Özlem BOYBEYİ; Mustafa ASLAN; Tutku SOYER; Mahi BALCI; Arkut DEMET; Ücler KISA; Murad BAŞAR; Murat ÇAKMAK

Article Details

Evaluating ESWL related alterations in renal pelvis and proximal ureter by analayting of tissue hydroxyproline levels

Authors:

Mine ŞENYÜCEL | Özlem BOYBEYİ | Mustafa ASLAN | Tutku SOYER | Mahi BALCI | Arkut DEMET | Ücler KISA | Murad BAŞAR | Murat ÇAKMAK

Publisher:

Ondokuz Mayıs University

Main Topics:

Promotion of health

Journal:

Journal of Experimental and Clinical Medicine 2015 Vol.32 Issue 1, pp.31-34

Document Type:

Article

Publication Date:

4/2015

Document Language:

English

Document ID (Org No.):

2000508429

Frequency:

Quarterly

eISSN:

1309-5129

pISSN:

1309-4483

Abstract:

 


The aim of the study is to evaluate extracorporeal shock wave lithotripsy (ESWL) related alterations in renal pelvis and proximal ureter by using histopathological methods and analayting hydroxy-proline levels. Twelve New-Zealand rabbits were allocated into two groups (n=6). Right sites of control group (CG, n=6) were harvested without any intervention. In ESWL group (EG), right kidneys of subjects were exposed to 3000 shock waves (14 kV) by using electro-hydraulic type ESWL device three times. Rabbits in EG were sacrificed on day 7. Tissues were examined histopathologically for presence of edema, inflammation, congestion, hemorrhage, fibrosis, vascularization and biochemically for hydroxyproline concentrations. Histopathologically, tissue edema was increased in renal pelvises and inflammation was increased in ureters in the EG compared to that in the CG (p0.05). Tissue collagen density did not show any significant difference (p>0.05). There was no difference in the tissue hydroxyl-proline levels of ureter samples (p>0.05). Tissue hydroxyproline levels were significantly higher in EG than CG in renal pelvis (p<0.05). In conclusion, although no major histopathological alteration due to ESWL was detected in renal pelvis and proximal ureter, increased hydroxyproline levels in the renal pelvis can be suggested as a finding of tissue injury in collecting system.

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Article Details

Evaluating ESWL related alterations in renal pelvis and proximal ureter by analayting of tissue hydroxyproline levels

Authors: Mine ŞENYÜCEL | Özlem BOYBEYİ | Mustafa ASLAN | Tutku SOYER | Mahi BALCI | Arkut DEMET | Ücler KISA | Murad BAŞAR | Murat ÇAKMAK

Publisher: Ondokuz Mayıs University

Main Topics: Promotion of health

Journal: Journal of Experimental and Clinical Medicine 2015 Vol.32 Issue 1, pp.31-34

Document Type: Article

Publication Date: 4/2015

Document Language: English

Document ID (Org No.): 2000508429

Frequency: Quarterly

eISSN: 1309-5129

pISSN: 1309-4483

Issues

Authors:

Mine ŞENYÜCEL | Özlem BOYBEYİ | Mustafa ASLAN | Tutku SOYER | Mahi BALCI | Arkut DEMET | Ücler KISA | Murad BAŞAR | Murat ÇAKMAK

Publisher:

Ondokuz Mayıs University

Main Topics:

Promotion of health

Journal:

Journal of Experimental and Clinical Medicine 2015 Vol.32 Issue 1, pp.31-34

Document Type:

Article

Publication Date:

4/2015

Document Language:

English

Document ID (Org No.):

2000508429

Frequency:

Quarterly

eISSN:

1309-5129

pISSN:

1309-4483