Studies on the Reactions of 4-Ethoxycarbonyl-5-phenyl-2,3-dihydro-2,3- furandione with Some NH Nucleophiles

Ahmet ŞENER; Hasan GENÇ; İsrafil TOZLU; M. Kasım ŞENER

Article Details

Studies on the Reactions of 4-Ethoxycarbonyl-5-phenyl-2,3-dihydro-2,3- furandione with Some NH Nucleophiles

Authors:

Ahmet ŞENER | Hasan GENÇ | İsrafil TOZLU | M. Kasım ŞENER

Publisher:

TUBITAK

Main Topics:

Applied physics

Journal:

Turkish Journal of Chemistry 2004 Vol.28 Issue 5, pp.659-666

Document Type:

Article

Publication Date:

4/2004

Document Language:

English

Document ID (Org No.):

2000729270

Frequency:

Bimonthly

eISSN:

1303-6130

pISSN:

1300-0527

Abstract:

 

4-Ethoxycarbonyl-5-phenyl-2,3-dihydro-2,3-furandione 1 was  reacted with o-phenylenediamine, substituted ureas and methylcarbamate  or acetamide to give quinoxaline 2, pyrimidine 3 and benzoylmalonic  acid 4 derivatives, respectively.  Benzoylmalonic acid derivative 4a  was converted into a new oxozinedione derivative, 5, by refluxing its  solution in xylene containing a catalytic amount of p-toluene sulfonic  acid.  In addition, triphenylpyrazole carboxylic acid derivative 6 was  obtained from the reaction of 4a with diphenylhydrazine.

 

4-Ethoxycarbonyl-5-phenyl-2,3-dihydro-2,3-furandione 1 was  reacted with o-phenylenediamine, substituted ureas and methylcarbamate  or acetamide to give quinoxaline 2, pyrimidine 3 and benzoylmalonic  acid 4 derivatives, respectively.  Benzoylmalonic acid derivative 4a  was converted into a new oxozinedione derivative, 5, by refluxing its  solution in xylene containing a catalytic amount of p-toluene sulfonic  acid.  In addition, triphenylpyrazole carboxylic acid derivative 6 was  obtained from the reaction of 4a with diphenylhydrazine.

Article Details

Studies on the Reactions of 4-Ethoxycarbonyl-5-phenyl-2,3-dihydro-2,3- furandione with Some NH Nucleophiles

Authors: Ahmet ŞENER | Hasan GENÇ | İsrafil TOZLU | M. Kasım ŞENER

Publisher: TUBITAK

Main Topics: Applied physics

Journal: Turkish Journal of Chemistry 2004 Vol.28 Issue 5, pp.659-666

Document Type: Article

Publication Date: 4/2004

Document Language: English

Document ID (Org No.): 2000729270

Frequency: Bimonthly

eISSN: 1303-6130

pISSN: 1300-0527

Issues

Authors:

Ahmet ŞENER | Hasan GENÇ | İsrafil TOZLU | M. Kasım ŞENER

Publisher:

TUBITAK

Main Topics:

Applied physics

Journal:

Turkish Journal of Chemistry 2004 Vol.28 Issue 5, pp.659-666

Document Type:

Article

Publication Date:

4/2004

Document Language:

English

Document ID (Org No.):

2000729270

Frequency:

Bimonthly

eISSN:

1303-6130

pISSN:

1300-0527