Comparison of the effects of hyperbaric and normobaric oxygen treatments on the repolarisation parameters of electrocardiography in children with carbon monoxide poisoning

Zafer BAĞCI; Abdullah ARSLAN; Derya ARSLAN; Ayşenur KOLSUZ

doi:https://doi.org/10.17826/cumj.983115

Article Details

Comparison of the effects of hyperbaric and normobaric oxygen treatments on the repolarisation parameters of electrocardiography in children with carbon monoxide poisoning

Authors:

Zafer BAĞCI | Abdullah ARSLAN | Derya ARSLAN | Ayşenur KOLSUZ

Publisher:

Cukurova University

Main Topics:

Diseases

Journal:

Cukurova Medical Journal 2021 Vol.46 Issue 4, pp.1606-1613

Document Type:

Article

Publication Date:

12/2021

Document Language:

English

Document ID (Org No.):

2000914500

Frequency:

Quarterly

eISSN:

2602-3040

pISSN:

2602-3032

DOI:

https://doi.org/10.17826/cumj.983115

Keywords:

Abstract:

 

Purpose: The aim of this study was to compare the effects of hyperbaric oxygen therapy (HBOT) induced hyper-oxygenation and normobaric oxygen therapy (NBOT) on myocardial repolarisation parameters in children with carbon monoxide (CO)  poisoning.
Materials and Methods: This prospective study included 77 girls and boys aged 0–18 years who were diagnosed and treated for CO poisoning. There were no changes in the routine clinical evaluation and treatment practices of patients. Patients who received NBOT (n=40) and HBOT (n=37) were divided into two groups. These groups were compared in terms of their demographic characteristics, carboxyhaemoglobin, lactate, troponin levels and myocardial repolarisation parameters of electrocardiography (ECG) (Tp-e interval, Tp-e dispersion, QTc and Tp-e/QTc ratio).
Results: There were no significant intergroup differences in terms of carboxyhaemoglobin, lactate and troponin levels at the time of admission; admission and post-treatment Tp-e, Tp-e dispersion, corrected QTc and TPe/QTc ratio and post-treatment change rates of each ECG parameter.
Conclusion: There was no intergroup difference in terms of repolarisation parameters of ECG in children with CO poisoning. The possible reason for this may be myocardial reperfusion damage due to hyper-oxygenation associated with HBOT therapy.

 

Amaç: Bu çalışmanın amacı, karbon monoksit (CO)  zehirlenmesi olan çocuklarda hiperbarik oksijen tedavisi (HBOT) ile oluşturulan hiperoksijenasyonun ve normobarik oksijen tedavisinin (NBOT) miyokardiyal repolarizasyon parametreleri üzerindeki etkilerini karşılaştırmaktı.
Gereç ve Yöntem: Bu prospektif çalışmaya CO zehirlenmesi tanısı konulan ve tedavi edilen 0-18 yaş arası kız ve erkek çocuklar dahil edildi. Hastaların rutin klinik değerlendirme ve tedavi uygulamalarında değişiklik olmadı. Hastalar NBOT yapılanlar (n=40) ve HBOT yapılanlar (n=37) olarak iki gruba ayrıldı. Bu gruplar, demografik özellikler, karboksihemoglobin, laktat, troponin düzeyleri ve elektrokardiyografinin (EKG)  miyokardiyal repolarizasyon parametreleri (Tp-e aralığı, Tp-e dispersiyonu, QTc ve Tp-e / QTc oranı) yönünden karşılaştırıldı.
Bulgular: Gruplar arasında başvurudaki COHb, laktat, troponin düzeyleri; başvuruda ve tedavi sonrası Tpe, Tpe dağılımı, düzeltilmiş QTc ve TPe/QTc oranları ve her bir EKG parametresinin tedavi sonrası değişim oranları yönünden anlamlı bir farklılık saptanmadı.
Sonuç: CO zehirlenmesi olan çocuklarda EKG repolarizasyon parametreleri açısından gruplar arasında fark yoktu. Bunun olası nedeni, HBOT tedavisi ile ilişkili hiperoksijenasyona bağlı miyokardiyal reperfüzyon hasarı olabilir.

Article Details

Comparison of the effects of hyperbaric and normobaric oxygen treatments on the repolarisation parameters of electrocardiography in children with carbon monoxide poisoning

Authors:

Zafer BAĞCI | Abdullah ARSLAN | Derya ARSLAN | Ayşenur KOLSUZ

Publisher:

Cukurova University

Main Topics:

Diseases

Journal:

Cukurova Medical Journal 2021 Vol.46 Issue 4, pp.1606-1613

Document Type:

Article

Publication Date:

12/2021

Document Language:

English

Document ID (Org No.):

2000914500

Frequency:

Quarterly

eISSN:

2602-3040

pISSN:

2602-3032

DOI:

https://doi.org/10.17826/cumj.983115

Karbonmonoksit zehirlenmesi

elektrokardiyografi

hiperbarik oksijen

çocuk

Issues

Article Details

Comparison of the effects of hyperbaric and normobaric oxygen treatments on the repolarisation parameters of electrocardiography in children with carbon monoxide poisoning

Authors: Zafer BAĞCI | Abdullah ARSLAN | Derya ARSLAN | Ayşenur KOLSUZ

Publisher: Cukurova University

Main Topics: Diseases

Journal: Cukurova Medical Journal 2021 Vol.46 Issue 4, pp.1606-1613

Document Type: Article

Publication Date: 12/2021

Document Language: English

Document ID (Org No.): 2000914500

Frequency: Quarterly

eISSN: 2602-3040

pISSN: 2602-3032

DOI: https://doi.org/10.17826/cumj.983115

Karbonmonoksit zehirlenmesi

elektrokardiyografi

hiperbarik oksijen

çocuk

Issues

Authors:

Zafer BAĞCI | Abdullah ARSLAN | Derya ARSLAN | Ayşenur KOLSUZ

Publisher:

Cukurova University

Main Topics:

Diseases

Journal:

Cukurova Medical Journal 2021 Vol.46 Issue 4, pp.1606-1613

Document Type:

Article

Publication Date:

12/2021

Document Language:

English

Document ID (Org No.):

2000914500

Frequency:

Quarterly

eISSN:

2602-3040

pISSN:

2602-3032

DOI:

https://doi.org/10.17826/cumj.983115