Obesity : An Enemy of Male Fertility : A Mini Review

Mohamed Ahmed Abd El Salam

doi:10.5001/omj.2018.02

Article Details

Obesity : An Enemy of Male Fertility : A Mini Review

Authors:

Mohamed Ahmed Abd El Salam

Publisher:

Oman Medical Specialty Board

Main Topics:

Medicine

Journal:

Oman Medical Journal 2018 Vol.33 Issue 1, pp.3-6

Document Type:

Article

Publication Date:

1/2018

Document Language:

English

Document ID (Org No.):

118347

Frequency:

Bi-Monthly

eISSN:

20705204

pISSN:

1999768X

DOI:

10.5001/omj.2018.02

Descriptors:

Keywords:

Abstract:

 Obesity is a highly prevalent non-communicable disease worldwide and is commonlyassociated with male infertility. Several etiopathological theories have been mentionedin the literature by which obesity affects spermatogenesis, thus affecting the male fertilitypotential. Mechanisms for explaining the effect of obesity on male infertility includeendocrinopathy, increased aromatization activity, associated erectile dysfunction,psychological and thermal effects, obstructive sleep apnea, increased leptin and oxygenfree radicals, and associated inflammatory and obstructive elements of epididymitis.Treatment of such a complex problem includes weight reduction (by lifestyle modificationand increased physical activity), optimization of altered testosterone-to-estradiol ratiousing aromatase inhibitors and/or gonadotropins, treatment of associated comorbiditiesby phosphodiesterase inhibitors for erectile dysfunction, and insulin-sensitizing agents forthe management of diabetes. The aim of this mini-review is to highlight the pathologicalbasis of this problem and to focus on obesity as an etiology of male infertility.

Article Details

Obesity : An Enemy of Male Fertility : A Mini Review

Authors:

Mohamed Ahmed Abd El Salam

Publisher:

Oman Medical Specialty Board

Main Topics:

Medicine

Journal:

Oman Medical Journal 2018 Vol.33 Issue 1, pp.3-6

Document Type:

Article

Publication Date:

1/2018

Document Language:

English

Document ID (Org No.):

118347

Frequency:

Bi-Monthly

eISSN:

20705204

pISSN:

1999768X

DOI:

10.5001/omj.2018.02

Descriptors:

OVERWEIGHT

FERTILITY

MALE INFERTILITY

SPERMATOGENESIS

PATIENTS

Body Mass Index

Male Infertility

Review

Obesity

Spermatogenesis

Issues

Article Details

Authors: Mohamed Ahmed Abd El Salam

Publisher: Oman Medical Specialty Board

Main Topics: Medicine

Journal: Oman Medical Journal 2018 Vol.33 Issue 1, pp.3-6

Document Type: Article

Publication Date: 1/2018

Document Language: English

Document ID (Org No.): 118347

Frequency: Bi-Monthly

eISSN: 20705204

pISSN: 1999768X

DOI: 10.5001/omj.2018.02

Descriptors:

Issues

Authors:

Mohamed Ahmed Abd El Salam

Publisher:

Oman Medical Specialty Board

Main Topics:

Medicine

Journal:

Oman Medical Journal 2018 Vol.33 Issue 1, pp.3-6

Document Type:

Article

Publication Date:

1/2018

Document Language:

English

Document ID (Org No.):

118347

Frequency:

Bi-Monthly

eISSN:

20705204

pISSN:

1999768X

DOI:

10.5001/omj.2018.02