Mean Platelet Volume in Patients with Chronic Venous Insufficiency

Mehmet Akif SARICA; Betül KIZILDAĞ; Mustafa Yavuz SELÇUK; Ayşe Şahin TUTAK; Ali Haydar BAYKAN; Hacı Taner BULUT; İbrahim Halil TÜRKBEYLER

doi:https://doi.org/10.5799/jcei.328685

Article Details

Mean Platelet Volume in Patients with Chronic Venous Insufficiency

Authors:

Mehmet Akif SARICA | Betül KIZILDAĞ | Mustafa Yavuz SELÇUK | Ayşe Şahin TUTAK | Ali Haydar BAYKAN | Hacı Taner BULUT | İbrahim Halil TÜRKBEYLER

Publisher:

Sağlık Araştırmaları Derneği

Main Topics:

Promotion of health

Journal:

Journal of Clinical and Experimental Investigations 2016 Vol.7 Issue 1, pp.73-77

Document Type:

Article

Publication Date:

2/2016

Document Language:

Turkish

Document ID (Org No.):

2000833256

Frequency:

Quarterly

eISSN:

1309-6621

pISSN:

1309-8578

DOI:

https://doi.org/10.5799/jcei.328685

Abstract:

 


Objective: the mean platelet volume (MPV) is a good indicator of platelet activity; it is reported to increase in diseases
associated with inflammatory processes and in vascular diseases. This study investigated the importance of mean platelet
volume in patients with chronic venous insufficiency (CVI) and whether the MPV was likely to be a predictor of the
CVI.
Methods: 117 patients who were diagnosed as CVI by colored Doppler Ultrasound (CDU) method and 49 healthy volunteers
(forming the control group) were enrolled to this study, which was planned retrospectively. The patients’ blood
count values taken within one month before and after the CDU evaluation were recorded by the hospital information
system. The complete blood count, routine biochemical tests and thyroid function tests of the patients diagnosed with
CVI were compared to the control group.
Results: Significant differences were not detected between the patients and the control group in terms of the levels
of creatinine, aspartate aminotransferase, total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, erythrocyte,
sedimentation speed, leukocyte, haemoglobin and thrombocyte (p>0.05). The thyroid stimulating hormone and the
MPV levels were significantly lower in the control group (p<0.05).
Conclusion: MPV levels as an easy, cheap and practical data extracted from complete blood count, were found higher
in patients diagnosed with CVI compared to the control group. This may be originated from endothelium changes as
an answer to venous hypertension and dilatation in CVI. MPV can be used as a follow-up marker in CVI patients. J Clin
Exp Invest 2016; 7 (1): 73-77

.

Article Details

Mean Platelet Volume in Patients with Chronic Venous Insufficiency

Authors: Mehmet Akif SARICA | Betül KIZILDAĞ | Mustafa Yavuz SELÇUK | Ayşe Şahin TUTAK | Ali Haydar BAYKAN | Hacı Taner BULUT | İbrahim Halil TÜRKBEYLER

Publisher: Sağlık Araştırmaları Derneği

Main Topics: Promotion of health

Journal: Journal of Clinical and Experimental Investigations 2016 Vol.7 Issue 1, pp.73-77

Document Type: Article

Publication Date: 2/2016

Document Language: Turkish

Document ID (Org No.): 2000833256

Frequency: Quarterly

eISSN: 1309-6621

pISSN: 1309-8578

DOI: https://doi.org/10.5799/jcei.328685

Issues

Authors:

Mehmet Akif SARICA | Betül KIZILDAĞ | Mustafa Yavuz SELÇUK | Ayşe Şahin TUTAK | Ali Haydar BAYKAN | Hacı Taner BULUT | İbrahim Halil TÜRKBEYLER

Publisher:

Sağlık Araştırmaları Derneği

Main Topics:

Promotion of health

Journal:

Journal of Clinical and Experimental Investigations 2016 Vol.7 Issue 1, pp.73-77

Document Type:

Article

Publication Date:

2/2016

Document Language:

Turkish

Document ID (Org No.):

2000833256

Frequency:

Quarterly

eISSN:

1309-6621

pISSN:

1309-8578

DOI:

https://doi.org/10.5799/jcei.328685