The Prevalence of Anti-HBC Antibody among HBS Ag-Negative Libyan Blood Donors and its Association with HBV DNA in the Serum

Albakosh, Abdalla Muftah; Alshwin, Farag Omar; Arshah, Tarek Mohamed

Article Details

The Prevalence of Anti-HBC Antibody among HBS Ag-Negative Libyan Blood Donors and its Association with HBV DNA in the Serum

Authors:

Albakosh, Abdalla Muftah | Alshwin, Farag Omar | Arshah, Tarek Mohamed

Publisher:

الجامعة الأسمرية الإسلامية زليتن - كليتى الآداب والعلوم

Journal:

مجلة العلوم الإنسانية والتطبيقية Vol.2017 Issue 30, pp.76-82

Document Type:

Article

Publication Date:

6/2017

Document Language:

English

Document ID (Org No.):

2001168778

Keywords:

Abstract:

 A hundred blood donors with hepatitis B surface antigen (HBs Ag) negative serology were enrolled in our study. These blood donors were investigated for the presence of antibodies to HBV core antigen (anti-HBc). Positive anti-HBc samples were further screened for anti-HBs antibodies, and for hepatitis B virus (HBV) DNA by real time Polymerase Chain Reaction technique.  Results: The donors found to be Anti-HBc positive were 14 (represent 14% of all donors), among them 11 were positive for both Anti-HBcantibodies and anti-HBs antibodies, while three donors were positive for Anti-HBc antibodies alone. All Anti-HBc positive samples were investigated by Polymerase Chain Reaction technique and found to be negative for HBV-DNA (which it might be attributed to low sensitivity of the used Polymerase Chain Reaction technique). Despite that, it would be much safer to introduce anti-HBc screening for blood donors and discard all blood units which are positive for anti-HBc alone.

Article Details

The Prevalence of Anti-HBC Antibody among HBS Ag-Negative Libyan Blood Donors and its Association with HBV DNA in the Serum

Authors:

Albakosh, Abdalla Muftah | Alshwin, Farag Omar | Arshah, Tarek Mohamed

Publisher:

الجامعة الأسمرية الإسلامية زليتن - كليتى الآداب والعلوم

Journal:

مجلة العلوم الإنسانية والتطبيقية Vol.2017 Issue 30, pp.76-82

Document Type:

Article

Publication Date:

6/2017

Document Language:

English

Document ID (Org No.):

2001168778

المضادات الحيوية

الحمض النووي

أمراض الدم

اللقاحات الطبية

Issues

Article Details

The Prevalence of Anti-HBC Antibody among HBS Ag-Negative Libyan Blood Donors and its Association with HBV DNA in the Serum

Authors: Albakosh, Abdalla Muftah | Alshwin, Farag Omar | Arshah, Tarek Mohamed

Publisher: الجامعة الأسمرية الإسلامية زليتن - كليتى الآداب والعلوم

Journal: مجلة العلوم الإنسانية والتطبيقية Vol.2017 Issue 30, pp.76-82

Document Type: Article

Publication Date: 6/2017

Document Language: English

Document ID (Org No.): 2001168778

المضادات الحيوية

الحمض النووي

أمراض الدم

اللقاحات الطبية

Issues

Authors:

Albakosh, Abdalla Muftah | Alshwin, Farag Omar | Arshah, Tarek Mohamed

Publisher:

الجامعة الأسمرية الإسلامية زليتن - كليتى الآداب والعلوم

Journal:

مجلة العلوم الإنسانية والتطبيقية Vol.2017 Issue 30, pp.76-82

Document Type:

Article

Publication Date:

6/2017

Document Language:

English

Document ID (Org No.):

2001168778