CHEMICAL COMPOSITION, ANTIOXIDANT AND HEMOLYTIC ACTIVITIES OF SAGE (SALVIA FRUTICOSA MILLER) CULTIVATED IN LEBANON

Sarah Karneeb; Safaa Baydoun; Hatem Nasser; Nelly Arnold-Apostolides; Mohammad H. El-Dakdouki

Article Details

CHEMICAL COMPOSITION, ANTIOXIDANT AND HEMOLYTIC ACTIVITIES OF SAGE (SALVIA FRUTICOSA MILLER) CULTIVATED IN LEBANON

Authors:

Sarah Karneeb | Safaa Baydoun | Hatem Nasser | Nelly Arnold-Apostolides | Mohammad H. El-Dakdouki

Publisher:

Beirut Arab University Press

Journal:

BAU Journal - Science and Technology Vol.4 Issue 2, pp.0-0

Document Type:

Article

Publication Date:

6/2023

Document Language:

English

Document ID (Org No.):

2001951539

pISSN:

2959-331X

Keywords:

Abstract:

 As part of the efforts contributing towards encouraging the cultivation of commercially valuable medicinal and aromatic plants and the conservation of vulnerable wild species suffering from depletion due to destructive unsustainable harvesting from the wild, we set out to assess the in vitro antioxidant activity, decipher the phytochemical profile, and evaluate the hemolytic activity of Salvia fruticosa Miller cultivated at Beirut Arab University herbal garden in Bekaa, Eastern Lebanon. The chemical compositions of the methanolic, aqueous and essential oil extracts were assessed by GC-MS analysis. In addition, the total phenolic, total flavonoid, total carbohydrate and total protein contents were determined for the methanolic and aqueous extracts. The antioxidant activity of all samples was evaluated using the DPPH radical scavenging, β-carotene bleaching, superoxide radical scavenging, reducing power and metal chelating activity assays. The overall analysis of data revealed that the methanolic and aqueous extracts exhibited potent antioxidant activity while the essential oil showed weak activity. Furthermore, strong correlation was found between the antioxidant activities and phytochemicals content. Finally, the cytotoxicity of the essential oil and extracts against human erythrocytes was assessed using the hemolysis assay. The aqueous extract did not show any hemolytic effect within the used concentration range. On the other hand, the methanolic extract showed a weak hemolytic activity, while the essential oil showed high hemolytic activity at the highest concentration used. The collective analysis of the data offered an encouraging evidence for the cultivation of commercially valuable medicinal aromatic plants (MAPs) such as S. fruticosa Miller as a supportive measure for the Lebanese economy.

Article Details

CHEMICAL COMPOSITION, ANTIOXIDANT AND HEMOLYTIC ACTIVITIES OF SAGE (SALVIA FRUTICOSA MILLER) CULTIVATED IN LEBANON

Authors:

Sarah Karneeb | Safaa Baydoun | Hatem Nasser | Nelly Arnold-Apostolides | Mohammad H. El-Dakdouki

Publisher:

Beirut Arab University Press

Journal:

BAU Journal - Science and Technology Vol.4 Issue 2, pp.0-0

Document Type:

Article

Publication Date:

6/2023

Document Language:

English

Document ID (Org No.):

2001951539

pISSN:

2959-331X

Cultivated Salvia fruticosa

GC-MS

Antioxidant activity

Total phenolic content

Total flavonoid content

Total carbohydrate content

Total protein content

Issues

Article Details

Authors: Sarah Karneeb | Safaa Baydoun | Hatem Nasser | Nelly Arnold-Apostolides | Mohammad H. El-Dakdouki

Publisher: Beirut Arab University Press

Journal: BAU Journal - Science and Technology Vol.4 Issue 2, pp.0-0

Document Type: Article

Publication Date: 6/2023

Document Language: English

Document ID (Org No.): 2001951539

pISSN: 2959-331X

Issues

Authors:

Sarah Karneeb | Safaa Baydoun | Hatem Nasser | Nelly Arnold-Apostolides | Mohammad H. El-Dakdouki

Publisher:

Beirut Arab University Press

Journal:

BAU Journal - Science and Technology Vol.4 Issue 2, pp.0-0

Document Type:

Article

Publication Date:

6/2023

Document Language:

English

Document ID (Org No.):

2001951539

pISSN:

2959-331X