Assessment of cutaneous and serum oxidative stress changes in dogs infested with Sarcoptes scabiei var canis

Onyeka Chidiebele NWUFOH; Nurudeen Ayinde SADİQ; Benjamin Obukowho EMİKPE; Tayo OMOBOWALE

Article Details

Assessment of cutaneous and serum oxidative stress changes in dogs infested with Sarcoptes scabiei var canis

Authors:

Onyeka Chidiebele NWUFOH | Nurudeen Ayinde SADİQ | Benjamin Obukowho EMİKPE | Tayo OMOBOWALE

Publisher:

İstanbul University-Cerrahpasa

Main Topics:

Animal husbandry

Journal:

Acta Veterinaria Eurasia 2019, pp.0-0

Document Type:

Article

Publication Date:

12/2018

Document Language:

English

Document ID (Org No.):

2000817088

Frequency:

Tri-annual

eISSN:

2619-905X

pISSN:

2618-639X

Abstract:

 

The evaluation of oxidative and anti-oxidative activities in skin and serum of scabietic dogs was studied. 20 healthy and 5 scabietic dogs were used. Healthy dogs were grouped as group A (Control; 10 dogs) and group B (10 dogs). Group B dogs were housed with the 5 scabietic dogs.
Hydrogen peroxide (H2O2), Glutathione peroxidase (GPX), Glutathione-S-transferase (GST), Superoxide dismutase (SOD), Reduced glutathione (GSH), and Total protein (TP) activities were weighed in skin and serum of healthy and scabietic dogs. Malonyldialdehyde (MDA) amount was measured in skin while Myeloperoxidase (MPO) amount was measured in serum of both healthy and scabietic dogs. Increase and decrease in free radical generation (H2O2) was noted with the use of serum and skin samples while GPX and SOD amounts in skin and serum was significantly higher in scabietic dogs. GST and GSH values were significantly higher in skin sample whereas GSH amount was not altered in serum. Total protein values decreased significantly in serum but decreased insignificantly in skin of infested dogs. MDA (skin) and MPO (serum) amounts were elevated in scabietic dogs.
Results showed that skin could be alternatives or complementary care samples in evaluation of oxidant, antioxidant balance, prognosis and monitoring of scabies therapy.

Cite this article as: Nwufoh, O.C., Sadiq, N.A., Emikpe, B.O., Omobowale, T., 2020. Assessment of cutaneous and serum oxidative stress changes in dogs infested with Sarcoptes scabiei var canis. Acta Vet Eurasia, DOI: 10.5152/actavet.2020.19010.

Article Details

Assessment of cutaneous and serum oxidative stress changes in dogs infested with Sarcoptes scabiei var canis

Authors: Onyeka Chidiebele NWUFOH | Nurudeen Ayinde SADİQ | Benjamin Obukowho EMİKPE | Tayo OMOBOWALE

Publisher: İstanbul University-Cerrahpasa

Main Topics: Animal husbandry

Journal: Acta Veterinaria Eurasia 2019, pp.0-0

Document Type: Article

Publication Date: 12/2018

Document Language: English

Document ID (Org No.): 2000817088

Frequency: Tri-annual

eISSN: 2619-905X

pISSN: 2618-639X

Issues

Authors:

Onyeka Chidiebele NWUFOH | Nurudeen Ayinde SADİQ | Benjamin Obukowho EMİKPE | Tayo OMOBOWALE

Publisher:

İstanbul University-Cerrahpasa

Main Topics:

Animal husbandry

Journal:

Acta Veterinaria Eurasia 2019, pp.0-0

Document Type:

Article

Publication Date:

12/2018

Document Language:

English

Document ID (Org No.):

2000817088

Frequency:

Tri-annual

eISSN:

2619-905X

pISSN:

2618-639X