Low Serum Cholesterol in Mice Pre-treated with Imperata cylindrica L. after Acute Olive Oil Gavage

Neni Anggraeni; Mas Rizky A.A Syamsunarno; Ghina Rahmadianti Mukarromah; Almira Zada; Rima Destya Triatin; Yunisa Pamela; Diah Dhianawaty

Article Details

Low Serum Cholesterol in Mice Pre-treated with Imperata cylindrica L. after Acute Olive Oil Gavage

Authors:

Neni Anggraeni | Mas Rizky A.A Syamsunarno | Ghina Rahmadianti Mukarromah | Almira Zada | Rima Destya Triatin | Yunisa Pamela | Diah Dhianawaty

Publisher:

KnE Social Sciences

Journal:

KnE Life Sciences Vol.3 Issue 6, pp.460-467

Document Type:

Article

Publication Date:

3/2017

Document Language:

English

Document ID (Org No.):

2001525531

pISSN:

2413-0877

Abstract:

 Imperata cylindrica L. extract was studied for its effect on cholesterol absorption rate in mice ( Mus muscularis ). Male mice (20-25g) were divided control and pre-treated group. Pretreated group was further divided into two groups that received different dose of Imperata cylindrica L. extract gavage (90mg/KgBW and 115mg/KgBW) for 2 weeks. Mice were fasted 12 hour before acutely given olive oil gavage with dosage of 10 µl/g, and blood was collected at 0, 2, and 6 hour-time points on the indicated day. Blood was collected from the retroorbital plexus at indicated time points. Total cholesterol level was significantly (p<0.05) decreased in both pretreated groups at 6 hours after acute olive oil gavage. In conclusion, there is a significant effect of Imperata cylindrica L. extract to reduce cholesterol level in serum, suggesting its potential effect as an antihypercholesterolemia therapy.

Article Details

Low Serum Cholesterol in Mice Pre-treated with Imperata cylindrica L. after Acute Olive Oil Gavage

Authors: Neni Anggraeni | Mas Rizky A.A Syamsunarno | Ghina Rahmadianti Mukarromah | Almira Zada | Rima Destya Triatin | Yunisa Pamela | Diah Dhianawaty

Publisher: KnE Social Sciences

Journal: KnE Life Sciences Vol.3 Issue 6, pp.460-467

Document Type: Article

Publication Date: 3/2017

Document Language: English

Document ID (Org No.): 2001525531

pISSN: 2413-0877

Issues

Authors:

Neni Anggraeni | Mas Rizky A.A Syamsunarno | Ghina Rahmadianti Mukarromah | Almira Zada | Rima Destya Triatin | Yunisa Pamela | Diah Dhianawaty

Publisher:

KnE Social Sciences

Journal:

KnE Life Sciences Vol.3 Issue 6, pp.460-467

Document Type:

Article

Publication Date:

3/2017

Document Language:

English

Document ID (Org No.):

2001525531

pISSN:

2413-0877