Application control region of human mitochondrial DNA in forensic anthropology

Somayyeh Samehsalari; K. Rajasekhara Reddy

Article Details

Application control region of human mitochondrial DNA in forensic anthropology

Authors:

Somayyeh Samehsalari | K. Rajasekhara Reddy

Publisher:

Tunisian Association of Anthropology

Journal:

International Journal of Modern Anthropology Vol.2 Issue 11, pp.233-248

Document Type:

Article

Publication Date:

1/2018

Document Language:

English

Document ID (Org No.):

2001614123

pISSN:

1737-8176

Keywords:

Abstract:

 Mitochondrial genome has particular features that make it a valuable forensic marker; first of all it is present in each somatic cell in high numbers. Therefore, it is more resistant to degradation and more stable under unfavorable conditions than nuclear DNA (nDNA) in highly damaged, degraded or very small quantity of the samples. Secondly, the high mutation rate, lack of recombination and the maternal mode of inheritance are features which make the mitochondrial DNA (mtDNA) better choice in situations where nDNA cannot be used for the analysis. Thus, forensic Anthropologists can determine how mitochondrial DNA may be best utilized in skeletal remains or hair shafts, which essentially lack nDNA but contain sufficient amounts of mtDNA. The most extensive mtDNA variations between individuals are found within the Control region or hypervariable regions (HVI, HVII, and HVIII) which allowed individuals to be differentiated and it could provide evidence about the identity of crime victims, especially skeletal remains. In this article we review the feature of mtDNA and its role as a reliable tool in Forensic Anthropology.Keywords: Forensic Anthropology, mitochondrial DNA, Hypervariable regions.

Article Details

Application control region of human mitochondrial DNA in forensic anthropology

Authors: Somayyeh Samehsalari | K. Rajasekhara Reddy

Publisher: Tunisian Association of Anthropology

Journal: International Journal of Modern Anthropology Vol.2 Issue 11, pp.233-248

Document Type: Article

Publication Date: 1/2018

Document Language: English

Document ID (Org No.): 2001614123

pISSN: 1737-8176

Forensic Anthropology

mitochondrial DNA

Hypervariable regions

Issues

Authors:

Somayyeh Samehsalari | K. Rajasekhara Reddy

Publisher:

Tunisian Association of Anthropology

Journal:

International Journal of Modern Anthropology Vol.2 Issue 11, pp.233-248

Document Type:

Article

Publication Date:

1/2018

Document Language:

English

Document ID (Org No.):

2001614123

pISSN:

1737-8176