Alkaloid profiling in Galanthus gracilis Celak. from western Turkey by GC/MS

Çiğdem KARAKOYUN

Article Details

Alkaloid profiling in Galanthus gracilis Celak. from western Turkey by GC/MS

Authors:

Çiğdem KARAKOYUN

Publisher:

Istanbul University

Main Topics:

Promotion of health

Journal:

İstanbul Journal of Pharmacy 2018 Vol.48 Issue 3, pp.73-75

Document Type:

Article

Publication Date:

11/2018

Document Language:

English

Document ID (Org No.):

2000513050

Frequency:

Monthly

eISSN:

2587-2087

Abstract:

 



DOI: 10.26650/IstanbulJPharm.2018.422525



Galanthus
L. is generally acknowledged as a valuable biological source due to its
Amaryllidaceae alkaloids with unusual chemical structures and a wide variety of
biological activities. Among these alkaloids, galanthamine is the first example
of their practical application in medicine as a potent and selective inhibitor
of the enzyme acetylcholinesterase, and already present on the market as a
therapeutic agent for Alzheimer’s disease. Lycorine is the main Amaryllidaceae
alkaloid deeply investigated for its biological activity for many years. In
this study the alkaloidal profile of G. gracilis collected from western Aegean
(Alankıyı/Bayındır) will be illustrated for the first time. GC-MS profiling was
carried out on the crude alkaloidal extract obtained from dried and powdered
plant material. 11 alkaloids were detected by GC-MS, including graciline,
demethylhomolycorine and tazettine as the major ones.


.

Article Details

Alkaloid profiling in Galanthus gracilis Celak. from western Turkey by GC/MS

Authors: Çiğdem KARAKOYUN

Publisher: Istanbul University

Main Topics: Promotion of health

Journal: İstanbul Journal of Pharmacy 2018 Vol.48 Issue 3, pp.73-75

Document Type: Article

Publication Date: 11/2018

Document Language: English

Document ID (Org No.): 2000513050

Frequency: Monthly

eISSN: 2587-2087

Issues

Authors:

Çiğdem KARAKOYUN

Publisher:

Istanbul University

Main Topics:

Promotion of health

Journal:

İstanbul Journal of Pharmacy 2018 Vol.48 Issue 3, pp.73-75

Document Type:

Article

Publication Date:

11/2018

Document Language:

English

Document ID (Org No.):

2000513050

Frequency:

Monthly

eISSN:

2587-2087