Platelet Lymphocyte Ratio is Associated With Carotid Atherosclerosis in Hemodialysis Patients

Yasemın KAYA; Mehmet YAMAN; Ahmet KARATAŞ; Tuba GÜL; Şükran KAYGISIZ; Hilal ALTAŞ; Ali YILMAZ; Ahmet KAYA

doi:https://doi.org/10.19127/mbsjohs.601400

Article Details

Platelet Lymphocyte Ratio is Associated With Carotid Atherosclerosis in Hemodialysis Patients

Authors:

Yasemın KAYA | Mehmet YAMAN | Ahmet KARATAŞ | Tuba GÜL | Şükran KAYGISIZ | Hilal ALTAŞ | Ali YILMAZ | Ahmet KAYA

Publisher:

Ordu University

Main Topics:

Promotion of health

Journal:

Middle Black Sea Journal of Health Science 2019 Vol.5 Issue 3, pp.199-205

Document Type:

Article

Publication Date:

12/2019

Document Language:

English

Document ID (Org No.):

2000564241

Frequency:

Tri-annual

eISSN:

2149-7796

DOI:

https://doi.org/10.19127/mbsjohs.601400

Abstract:

 


Objective: We aimed to demonstrate whether there is a correlation
between Platelet Lymphocyte Ratio (PLR) and carotid intima-media thickness
(CIMT) which is an early marker of atherosclerosis in patients receiving
dialysis where there is a chronic inflammatory process in the body.


Methods: 53 patients receiving dialysis 3 days a week and 54
persons as the control group were included. The exclusion criteria were determined
as infection, using drugs that increase or decrease the number of leukocytes
such as steroids, antithyroid, chronic liver diseases, rheumatic disease,
maling disease and prior cardiovascular or cerebrovascular diseases. Patients’
age, gender, body mass index, hemogram and biochemical parameters were
recorded. CIMT values were measured by Carotid Doppler examination.


Results: When the two groups were compared; there was no
significant difference between them in terms of age, gender, blood pressures,
DM, ejection fractions, lipid levels. PLR, neutrophil-to-lymphocyte ratio (NLR)
and CIMT were significantly higher (p=0.009, p<0.001, p<0.001;
respectively) in the dialysis patients group. A positive correlation was found
between CIMT and PLR, NLR (r=0.59 p<0.001, r=0.38, p=0.004). As a result of
the linear regression analysis, PLR (B:0.714, 95%CI:3.425/14.393, p=0.002) and
NLR were found as independent predictors in showing CIMT.









Conclusion: PLR is independently associated with subclinical
atherosclerosis assessed by CIMT in people with dialysis patients




.

Article Details

Platelet Lymphocyte Ratio is Associated With Carotid Atherosclerosis in Hemodialysis Patients

Authors: Yasemın KAYA | Mehmet YAMAN | Ahmet KARATAŞ | Tuba GÜL | Şükran KAYGISIZ | Hilal ALTAŞ | Ali YILMAZ | Ahmet KAYA

Publisher: Ordu University

Main Topics: Promotion of health

Journal: Middle Black Sea Journal of Health Science 2019 Vol.5 Issue 3, pp.199-205

Document Type: Article

Publication Date: 12/2019

Document Language: English

Document ID (Org No.): 2000564241

Frequency: Tri-annual

eISSN: 2149-7796

DOI: https://doi.org/10.19127/mbsjohs.601400

Issues

Authors:

Yasemın KAYA | Mehmet YAMAN | Ahmet KARATAŞ | Tuba GÜL | Şükran KAYGISIZ | Hilal ALTAŞ | Ali YILMAZ | Ahmet KAYA

Publisher:

Ordu University

Main Topics:

Promotion of health

Journal:

Middle Black Sea Journal of Health Science 2019 Vol.5 Issue 3, pp.199-205

Document Type:

Article

Publication Date:

12/2019

Document Language:

English

Document ID (Org No.):

2000564241

Frequency:

Tri-annual

eISSN:

2149-7796

DOI:

https://doi.org/10.19127/mbsjohs.601400