Electrochemical oxidation of curcuminoids: an experimental and computational   investigation

Zeynep KALAYCIOĞLU; Nurgül KARADAŞ; Mehmet Emin ÇINAR; Sibel Ayşil ÖZKAN; Durişehvar Özer ÜNAL; Ayşegül GÖLCÜ; Fatma Bedia ERİM

Article Details

Electrochemical oxidation of curcuminoids: an experimental and computational investigation

Authors:

Zeynep KALAYCIOĞLU | Nurgül KARADAŞ | Mehmet Emin ÇINAR | Sibel Ayşil ÖZKAN | Durişehvar Özer ÜNAL | Ayşegül GÖLCÜ | Fatma Bedia ERİM

Publisher:

TUBITAK

Journal:

Turkish Journal of Chemistry 2019 Vol.43 Issue 3, pp.834-845

Document Type:

Article

Publication Date:

5/2019

Document Language:

Turkish

Document ID (Org No.):

2000725728

Frequency:

Bimonthly

eISSN:

1303-6130

pISSN:

1300-0527

Abstract:

 

Curcuminoids, reported to have important biological properties, such as   antioxidant, anti-Alzheimer, and antidiabetic properties, comprise curcumin   (CRM; 1,7-bis [4-hydroxy-3-methoxyphenyl]-1,6-heptadiene-3,5-dione) and its   derivatives demethoxycurcumin (DMC;   (E,6E)-1-(3,4-dimethoxy-cyclohexyl)-7-(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione)   and bisdemethoxycurcumin (BDMC;   1,7-bis[4-hydroxyphenyl]-1,6-heptadiene-3,5-dione). Their electrochemical   oxidations are thoroughly explored by applying cyclic and differential pulse   voltammetric techniques. The dependence of current intensities and   potentials on pH, concentration, scan rate, and nature of the buffer was   investigated. The outcome is supported by density functional theory   computations indicating the transfer of 4-e−−^{-}/H++^{+},   6-e−−^{-}/H++^{+}, and 8-e−−^{-}/H++^{+} couples involved in the oxidation   mechanisms of CRM, DMC, and BDMC, respectively, leading to the formation of   the same oxidized product.

Article Details

Electrochemical oxidation of curcuminoids: an experimental and computational investigation

Authors: Zeynep KALAYCIOĞLU | Nurgül KARADAŞ | Mehmet Emin ÇINAR | Sibel Ayşil ÖZKAN | Durişehvar Özer ÜNAL | Ayşegül GÖLCÜ | Fatma Bedia ERİM

Publisher: TUBITAK

Journal: Turkish Journal of Chemistry 2019 Vol.43 Issue 3, pp.834-845

Document Type: Article

Publication Date: 5/2019

Document Language: Turkish

Document ID (Org No.): 2000725728

Frequency: Bimonthly

eISSN: 1303-6130

pISSN: 1300-0527

Issues

Authors:

Zeynep KALAYCIOĞLU | Nurgül KARADAŞ | Mehmet Emin ÇINAR | Sibel Ayşil ÖZKAN | Durişehvar Özer ÜNAL | Ayşegül GÖLCÜ | Fatma Bedia ERİM

Publisher:

TUBITAK

Journal:

Turkish Journal of Chemistry 2019 Vol.43 Issue 3, pp.834-845

Document Type:

Article

Publication Date:

5/2019

Document Language:

Turkish

Document ID (Org No.):

2000725728

Frequency:

Bimonthly

eISSN:

1303-6130

pISSN:

1300-0527