Prevalence of Bacteremia in Critical Care Unit and Drug Resistance

Al-Habashneh , Muen; Abu-Zeid , Ahmad

Article Details

Prevalence of Bacteremia in Critical Care Unit and Drug Resistance

Authors:

Al-Habashneh , Muen | Abu-Zeid , Ahmad

Publisher:

medi+WORLD International

Main Topics:

Medicine

Journal:

Middle East Journal of Internal Medicine 2010 vol.3 Issue 1, pp.7-11

Document Type:

Article

Publication Date:

6/2010

Document Language:

English

Document ID (Org No.):

17481

Frequency:

Quarterly

eISSN:

18379060

pISSN:

18379052

Descriptors:

Keywords:

Abstract:

 Objective: To determine the pattern of antibiotic resistance among gram-negative bacteria in relation to antibiotic use in ICU admission in King Hussein Medical Center (KHMC)-Jordan
Materials and Methods: One hundred consecutive gram-negative bacterial isolates from different sites were collected from patients admitted to the ICU at KHMC. The susceptibilities of the strains to 12 antibiotics were performed and interpreted. The quantities and the numbers of the patients discharged on antibiotics and the quantities consumed were obtained from the hospital pharmacy records.
Results: The most common isolate was P. aeruginosa (n=21). The most common site of isolation was the respiratory tract (65%). The highest susceptibility was to piperacillin/ tazobactam (78%), and the lowest was to cefuroxime (34%). The aminoglycosides gentamicin and amikacin were active against 71% and 73% of the isolates respectively; Ciprofloxacin was active against 75% of the isolates. The most frequently used antibiotics were the third-generation cephalosporins ceftriaxone and ceftazidime, followed by imipenem and amikacin.
Conclusion: Antibiotic resistance surveillance programs associated with registration of antibiotic consumption are necessary to promote optimal use of antibiotics. Rational prescribing of antibiotics should be encouraged through educational programs, surveillance and audit. Proper infection control measures should be practiced to prevent horizontal transfer of drug-resistant organisms.

Article Details

Prevalence of Bacteremia in Critical Care Unit and Drug Resistance

Authors:

Al-Habashneh , Muen | Abu-Zeid , Ahmad

Publisher:

medi+WORLD International

Main Topics:

Medicine

Journal:

Middle East Journal of Internal Medicine 2010 vol.3 Issue 1, pp.7-11

Document Type:

Article

Publication Date:

6/2010

Document Language:

English

Document ID (Org No.):

17481

Frequency:

Quarterly

eISSN:

18379060

pISSN:

18379052

Descriptors:

GRAM NEGATIVE BACTERIA

ANTIBIOTICS

ANTIBIOTIC RESISTANT BACTERIA

CRITICAL CARE

INFECTIOUS DISEASES

INFECTION

INFECTION CONTROL

DISEASE RESISTANCE

PATIENTS

HOSPITALS

JORDAN

Antibiotic

Resistance

Gram-Negative Bacilli

Issues

Article Details

Authors: Al-Habashneh , Muen | Abu-Zeid , Ahmad

Publisher: medi+WORLD International

Main Topics: Medicine

Journal: Middle East Journal of Internal Medicine 2010 vol.3 Issue 1, pp.7-11

Document Type: Article

Publication Date: 6/2010

Document Language: English

Document ID (Org No.): 17481

Frequency: Quarterly

eISSN: 18379060

pISSN: 18379052

Descriptors:

Issues

Authors:

Al-Habashneh , Muen | Abu-Zeid , Ahmad

Publisher:

medi+WORLD International

Main Topics:

Medicine

Journal:

Middle East Journal of Internal Medicine 2010 vol.3 Issue 1, pp.7-11

Document Type:

Article

Publication Date:

6/2010

Document Language:

English

Document ID (Org No.):

17481

Frequency:

Quarterly

eISSN:

18379060

pISSN:

18379052