Microstructure Investigations on PLA-Based Nanofiber Surfaces Containing Biocompatible Additives Produced by Electrospinning Method

Nihat Tosun; Dilan Şen Ulusal; Gül Tosun

Article Details

Microstructure Investigations on PLA-Based Nanofiber Surfaces Containing Biocompatible Additives Produced by Electrospinning Method

Authors:

Nihat Tosun | Dilan Şen Ulusal | Gül Tosun

Publisher:

Afyon Kocatepe University

Main Topics:

Mühendislik | Biyomateryaller | Kompozit ve Hibrit Malzemeler

Journal:

Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi Vol.23 Issue 6, pp.1525-1532

Document Type:

Article

Publication Date:

12/2023

Document Language:

Turkish

Document ID (Org No.):

2001305872

pISSN:

2149-3367

Keywords:

Abstract:

 In this study, different solutions with different concentrations and mixing ratios were prepared using titanium dioxide TiO2, hydroxyapatite HA and polylactic acid PLA with good biocompatibility rates for use as medical and biomaterials, and nanofibrous surfaces were produced from these different solutions using electrospinning method in fixed process parameters. The characteristic properties of the nanofiber surfaces produced were determined by Scanning Electron Microscopy SEM and EDX analysis. From experimental results, it was determined that the increase in the amount of HA or TiO2 increased the bead formation and fiber diameters. When the FT-IR analysis results were examined, no unusual difference was found in all test results.

 In this study, different solutions with different concentrations and mixing ratios were prepared using titanium dioxide TiO2, hydroxyapatite HA and polylactic acid PLA with good biocompatibility rates for use as medical and biomaterials, and nanofibrous surfaces were produced from these different solutions using electrospinning method in fixed process parameters. The characteristic properties of the nanofiber surfaces produced were determined by Scanning Electron Microscopy SEM and EDX analysis. From experimental results, it was determined that the increase in the amount of HA or TiO2 increased the bead formation and fiber diameters. When the FT-IR analysis results were examined, no unusual difference was found in all test results.

 In this study, different solutions with different concentrations and mixing ratios were prepared using titanium dioxide TiO2, hydroxyapatite HA and polylactic acid PLA with good biocompatibility rates for use as medical and biomaterials, and nanofibrous surfaces were produced from these different solutions using electrospinning method in fixed process parameters. The characteristic properties of the nanofiber surfaces produced were determined by Scanning Electron Microscopy SEM and EDX analysis. From experimental results, it was determined that the increase in the amount of HA or TiO2 increased the bead formation and fiber diameters. When the FT-IR analysis results were examined, no unusual difference was found in all test results.

 Bu çalışmada, tıbbi ve biyomalzeme olarak kullanılmak üzere biyouyumluluk oranları iyi olan farklı özelliklere sahip titanyum dioksit TiO2, hidroksi apatit HA ve polilaktik asit PLA kullanılarak farklı konsantrasyon ve karışım oranlarında farklı çözeltiler hazırlanmış ve bu farklı çözeltilerden sabit proses parametrelerinde elektro çekim yöntemi kullanılarak nanolifli yüzeyler üretildi. Üretilen nanolif örtülerin karakteristik özellikleri, Taramalı Elektron Mikroskobu SEM ve EDX analizleri ile belirlendi. Deney sonuçlarından, HA veya TiO2 miktarındaki artışının boncuk oluşumunu ve lif çaplarını arttırdığı tespit edilmiştir. FT-IR analiz sonuçları incelendiğinde tüm deney sonuçlarında olağandışı bir farklılığa rastlanmamıştır.

Article Details

Microstructure Investigations on PLA-Based Nanofiber Surfaces Containing Biocompatible Additives Produced by Electrospinning Method

Authors:

Nihat Tosun | Dilan Şen Ulusal | Gül Tosun

Publisher:

Afyon Kocatepe University

Main Topics:

Mühendislik | Biyomateryaller | Kompozit ve Hibrit Malzemeler

Journal:

Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi Vol.23 Issue 6, pp.1525-1532

Document Type:

Article

Publication Date:

12/2023

Document Language:

Turkish

Document ID (Org No.):

2001305872

pISSN:

2149-3367

Electrospinning

Nanofiber

Polylactic acid

Hydroxyapatite

Titanium dioxideElektroçekim

Nanolif

Polilaktik asit

Hidroksiapatit

Titanyum dioksit

Issues

Article Details

Authors: Nihat Tosun | Dilan Şen Ulusal | Gül Tosun

Publisher: Afyon Kocatepe University

Main Topics: Mühendislik | Biyomateryaller | Kompozit ve Hibrit Malzemeler

Journal: Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi Vol.23 Issue 6, pp.1525-1532

Document Type: Article

Publication Date: 12/2023

Document Language: Turkish

Document ID (Org No.): 2001305872

pISSN: 2149-3367

Issues

Authors:

Nihat Tosun | Dilan Şen Ulusal | Gül Tosun

Publisher:

Afyon Kocatepe University

Main Topics:

Mühendislik | Biyomateryaller | Kompozit ve Hibrit Malzemeler

Journal:

Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi Vol.23 Issue 6, pp.1525-1532

Document Type:

Article

Publication Date:

12/2023

Document Language:

Turkish

Document ID (Org No.):

2001305872

pISSN:

2149-3367