The effect of experimentally induced carbon dioxide pneumoperitoneum on intra-abdominal and intra-esophageal pH

Tutku SOYER

Article Details

The effect of experimentally induced carbon dioxide pneumoperitoneum on intra-abdominal and intra-esophageal pH

Authors:

Tutku SOYER

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2009 Vol.39 Issue 5, pp.709-712

Document Type:

Article

Publication Date:

4/2009

Document Language:

Turkish

Document ID (Org No.):

2000755311

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Keywords:

Abstract:

 

Aim: An experimental study was performed to evaluate the effect of CO2 pneumoperitoneum on intra-abdominal (IA) and intra-esophageal (IE) pH.  Material and methods: The study included 18 Wistar rats. In the control group (n = 6) a pH catheter was inserted into the peritoneal cavity via a left upper quadrant incision and another catheter was inserted into the lower esophagus via the oral route. Pre- and post-insufflation IA and IE pH were recorded every 5 min for 1 h. In the experimental groups, in addition to pH catheters, a 16-G catheter was inserted into the abdomen above the umbilicus. In the O2 group (n = 6) 95% O2 and 5% CO2 were insufflated with a pressure of 10 mmHg. In the CO2 group (n = 6), CO2 was insufflated with the same pressure and duration.   Results: In the CO2 group, IA and IE pH values significantly decreased (P < 0.05). IA pH values decreased in the CO2 group when compared to the control and O2 groups (P < 0.05). There was not a significant difference in IE pH between the CO2 group and the other groups.   Conclusion: CO2 insufflation decreased IA pH values. Decreased pH values obtained with continuous recordings of the esophagus may have been related to increases in intra-abdominal pressure, rather than the metabolic effects of CO2 pneumoperitoneum.

 

Aim: An experimental study was performed to evaluate the effect of CO2 pneumoperitoneum on intra-abdominal (IA) and intra-esophageal (IE) pH.  Material and methods: The study included 18 Wistar rats. In the control group (n = 6) a pH catheter was inserted into the peritoneal cavity via a left upper quadrant incision and another catheter was inserted into the lower esophagus via the oral route. Pre- and post-insufflation IA and IE pH were recorded every 5 min for 1 h. In the experimental groups, in addition to pH catheters, a 16-G catheter was inserted into the abdomen above the umbilicus. In the O2 group (n = 6) 95% O2 and 5% CO2 were insufflated with a pressure of 10 mmHg. In the CO2 group (n = 6), CO2 was insufflated with the same pressure and duration.   Results: In the CO2 group, IA and IE pH values significantly decreased (P < 0.05). IA pH values decreased in the CO2 group when compared to the control and O2 groups (P < 0.05). There was not a significant difference in IE pH between the CO2 group and the other groups.   Conclusion: CO2 insufflation decreased IA pH values. Decreased pH values obtained with continuous recordings of the esophagus may have been related to increases in intra-abdominal pressure, rather than the metabolic effects of CO2 pneumoperitoneum.

Article Details

The effect of experimentally induced carbon dioxide pneumoperitoneum on intra-abdominal and intra-esophageal pH

Authors:

Tutku SOYER

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2009 Vol.39 Issue 5, pp.709-712

Document Type:

Article

Publication Date:

4/2009

Document Language:

Turkish

Document ID (Org No.):

2000755311

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Key words: Carbon dioxide

pH

pneumoperitoneum

esophagus

abdomen

Issues

Article Details

The effect of experimentally induced carbon dioxide pneumoperitoneum on intra-abdominal and intra-esophageal pH

Authors: Tutku SOYER

Publisher: TUBITAK

Journal: Turkish Journal of Medical Sciences 2009 Vol.39 Issue 5, pp.709-712

Document Type: Article

Publication Date: 4/2009

Document Language: Turkish

Document ID (Org No.): 2000755311

Frequency: Bimonthly

eISSN: 1303-6165

pISSN: 1300-0144

Key words: Carbon dioxide

pH

pneumoperitoneum

esophagus

abdomen

Issues

Authors:

Tutku SOYER

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2009 Vol.39 Issue 5, pp.709-712

Document Type:

Article

Publication Date:

4/2009

Document Language:

Turkish

Document ID (Org No.):

2000755311

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144