Sesame Oil Has Gastroprotective And Anti-Oxidative Properties: An Experimental Study In Rats With Indomethacin-Induced Gastric Ulcers

Nurulhünda HANCI; Fehmi ODABASOGLU; Fadime ATALAY DUMLU; Ozlem AYDIN BERKTAŞ; Zerrin KUTLU; Mesut HALİCİ; Zekai HALİCİ

Article Details

Sesame Oil Has Gastroprotective And Anti-Oxidative Properties: An Experimental Study In Rats With Indomethacin-Induced Gastric Ulcers

Authors:

Nurulhünda HANCI | Fehmi ODABASOGLU | Fadime ATALAY DUMLU | Ozlem AYDIN BERKTAŞ | Zerrin KUTLU | Mesut HALİCİ | Zekai HALİCİ

Publisher:

İlknur BAĞDATLI

Main Topics:

Food technology

Journal:

Eurasian Journal of Food Science and Technology 2018 Vol.2 Issue 2, pp.53-68

Document Type:

Article

Publication Date:

12/2018

Document Language:

English

Document ID (Org No.):

2000422346

eISSN:

2667-4890

Abstract:

 


Sesame
oil (SO) is a component of the traditional health food in India as well as in
oriental countries and has long been thought to possess the ability to prevent
various diseases. We examined the protective effects of sesame oil against
acute gastric mucosal damage induced in rats by nonsteroidal anti-inflammatory
drug indomethacin (IND). We also intended to determine the relation between
antiulcer effect of SO and its antioxidant properties by biochemical
evaluation. In this study a total of 5 rat groups were used for ulcer
experiment. Antiulcer effects of SO have been investigated on 24 hour fasted 5
rat groups with indomethacine (IND)-induced ulcer model in the presence of
positive (Famotidine, FAM), negative (untreated IND group) and intact control
groups. In ulcer experiments, two doses of SO exerted significant
anti-ulcerogenic effects. In gastric tissues, sesame oil administration
decreased the level of LPO and activities of CAT, GR, MPO which were increased
after IND application. Furthermore, SO increased the level of GSH which
decreased in ulcerous stomach tissues when compared to healthy rat group. We
determined that SO has anti-ulcerative effect and this effect are related to
antioxidative properties of sesame oil.


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Article Details

Sesame Oil Has Gastroprotective And Anti-Oxidative Properties: An Experimental Study In Rats With Indomethacin-Induced Gastric Ulcers

Authors: Nurulhünda HANCI | Fehmi ODABASOGLU | Fadime ATALAY DUMLU | Ozlem AYDIN BERKTAŞ | Zerrin KUTLU | Mesut HALİCİ | Zekai HALİCİ

Publisher: İlknur BAĞDATLI

Main Topics: Food technology

Journal: Eurasian Journal of Food Science and Technology 2018 Vol.2 Issue 2, pp.53-68

Document Type: Article

Publication Date: 12/2018

Document Language: English

Document ID (Org No.): 2000422346

eISSN: 2667-4890

Issues

Authors:

Nurulhünda HANCI | Fehmi ODABASOGLU | Fadime ATALAY DUMLU | Ozlem AYDIN BERKTAŞ | Zerrin KUTLU | Mesut HALİCİ | Zekai HALİCİ

Publisher:

İlknur BAĞDATLI

Main Topics:

Food technology

Journal:

Eurasian Journal of Food Science and Technology 2018 Vol.2 Issue 2, pp.53-68

Document Type:

Article

Publication Date:

12/2018

Document Language:

English

Document ID (Org No.):

2000422346

eISSN:

2667-4890