The Pattern of Antibiotic Resistance of Common Bacteria Causing Nosocomial Infections

Mojtaba Hedayat Yaghoobi; Mohammad Reza Arabestani; Pezhman Karami; Azad Khaledi; Mohamad Ali Seifrabie; Omid Khiabanchian; Farshid Rahimi-Bashar

doi:10.5742/MEWFM.2018.93342

Article Details

The Pattern of Antibiotic Resistance of Common Bacteria Causing Nosocomial Infections

Authors:

Mojtaba Hedayat Yaghoobi | Mohammad Reza Arabestani | Pezhman Karami | Azad Khaledi | Mohamad Ali Seifrabie | Omid Khiabanchian | Farshid Rahimi-Bashar

Publisher:

medi+WORLD International

Main Topics:

Medicine

Journal:

World Family Medicine Journal: Incorporating the Middle East Journal of Family Medicine 2018 Vol.16 Issue 3, pp.172-178

Document Type:

Article

Publication Date:

3/2018

Document Language:

English

Document ID (Org No.):

117613

Frequency:

Monthly

eISSN:

18390196

pISSN:

18390188

DOI:

10.5742/MEWFM.2018.93342

Descriptors:

Keywords:

Abstract:

 Background: Nosocomial infection is one of the most important health problems across the world. Nosocomial infection causes 99,000 deaths and patients spend over 30 million dollars per year in America. The current study aimed to determine the pattern of antibiotic resistance of common bacteria causing nosocomial infections in Besat Hospital, Hamedan, Iran.Methods: This cross sectional prospective study was conducted in Besat hospital for four months. Each of the non-pediatric patients in different wards of the hospital with various types of nosocomial infections in accordance with CDC guidelines were enrolled, and cultured chip samples, urine, blood and wound specimens for culture and susceptibility were sent to a laboratory. All micro-organisms isolated from cultures were considered in antimicrobial resistance patterns. Antimicrobial resistance pattern (Kirby-Bauer method) of bacterial isolates was determined according to the report/ test table of CLSI M100-S23 instructions.Results: Of 10,332 hospitalized patients we reported 266 (2.6%) with nosocomial infections and the VAP was the most common nosocomial infection.Among 266 bacterial isolates, the highest prevalent bacterium belonged to the E. coli with prevalence 61(22.9%) followed by Klebsiella, Acinetobacter and S. aureus with prevalence of 42(15.8%), 36(13.5%) and 26(9.8%), respectively.In Gram-negative bacteria maximum resistance to ciprofloxacin and minimum resistance to Colistin and Imipenem was observed. The prevalence of MRSA in VAP, CLA-BSI and SSI was 3.3, 22.2 and 54.5 %. Resistance to Vancomycin in Staphylococci was not observed, but in Enterococci resistance to Vancomycin was 42.9%.Conclusion: The main problem in this hospital is MDR Gram-negative infections rather than Staphylococcus aureus.Knowing the pattern of antimicrobial resistance can prevent prescribing inappropriate antibiotics and effective steps can be taken towards reducing microbial resistance.

Article Details

The Pattern of Antibiotic Resistance of Common Bacteria Causing Nosocomial Infections

Authors:

Mojtaba Hedayat Yaghoobi | Mohammad Reza Arabestani | Pezhman Karami | Azad Khaledi | Mohamad Ali Seifrabie | Omid Khiabanchian | Farshid Rahimi-Bashar

Publisher:

medi+WORLD International

Main Topics:

Medicine

Journal:

World Family Medicine Journal: Incorporating the Middle East Journal of Family Medicine 2018 Vol.16 Issue 3, pp.172-178

Document Type:

Article

Publication Date:

3/2018

Document Language:

English

Document ID (Org No.):

117613

Frequency:

Monthly

eISSN:

18390196

pISSN:

18390188

DOI:

10.5742/MEWFM.2018.93342

Descriptors:

NOSOCOMIAL DISEASES

INFECTION

BACTERIA

ANTIBIOTICS

ANTIMICROBIALS

PATIENTS

HOSPITALS

IRAN

Antibiotic Resistance

Nosocomial

Infection

Drug Resistance

Issues

Article Details

Authors: Mojtaba Hedayat Yaghoobi | Mohammad Reza Arabestani | Pezhman Karami | Azad Khaledi | Mohamad Ali Seifrabie | Omid Khiabanchian | Farshid Rahimi-Bashar

Publisher: medi+WORLD International

Main Topics: Medicine

Journal: World Family Medicine Journal: Incorporating the Middle East Journal of Family Medicine 2018 Vol.16 Issue 3, pp.172-178

Document Type: Article

Publication Date: 3/2018

Document Language: English

Document ID (Org No.): 117613

Frequency: Monthly

eISSN: 18390196

pISSN: 18390188

DOI: 10.5742/MEWFM.2018.93342

Descriptors:

Issues

Authors:

Mojtaba Hedayat Yaghoobi | Mohammad Reza Arabestani | Pezhman Karami | Azad Khaledi | Mohamad Ali Seifrabie | Omid Khiabanchian | Farshid Rahimi-Bashar

Publisher:

medi+WORLD International

Main Topics:

Medicine

Journal:

World Family Medicine Journal: Incorporating the Middle East Journal of Family Medicine 2018 Vol.16 Issue 3, pp.172-178

Document Type:

Article

Publication Date:

3/2018

Document Language:

English

Document ID (Org No.):

117613

Frequency:

Monthly

eISSN:

18390196

pISSN:

18390188

DOI:

10.5742/MEWFM.2018.93342