Efficacy of Intravenous Tranexamic Acid in Reducing Blood Loss after Elective Cesarean Section

Ali , Samir Abd Allah; Oof , Tamer Fares; Elmolla , Mohamed Fouad

Article Details

Efficacy of Intravenous Tranexamic Acid in Reducing Blood Loss after Elective Cesarean Section

Authors:

Ali , Samir Abd Allah | Oof , Tamer Fares | Elmolla , Mohamed Fouad

Publisher:

Pan Arab League of Continuous Medical Education

Main Topics:

Medicine

Journal:

The Egyptian Journal of Hospital Medicine 2019 Vol.74 Issue 6, pp.1353-1358

Document Type:

Article

Publication Date:

1/2019

Document Language:

English

Document ID (Org No.):

136839

Frequency:

Quarterly

eISSN:

20907125

pISSN:

16872002

Descriptors:

Keywords:

Abstract:

 Background: Primary post-partum hemorrhage (PPH) is defined as blood loss greater than or equal to 500 ml within 24 hours after birth, while severe PPH is blood loss greater than or equal to 1000 ml within 24 hours.Objective: was to determine the efficacy and safety of tranexamic acid in reduction of blood loss after the elective cesarean sections.Patients and Methods: We performed a randomized, controlled study of 200 pregnant females who underwent elective CS. The patients had attended the Labor Ward in Al-Azhar University Maternity Hospital. 100 of them received tranexamic acid 20 minutes before beginning of anesthesia in addition to oxytocin after delivery of the baby; the other 100 patients received oxytocin only.Results: In the 1st two hours post-partum vaginal bleeding was significantly less severe in study group than control group (p<0.019). There was nonsignificant difference between study and control groups as regards preoperative hemoglobin concentration (p=0.195), Postoperative hemoglobin concentration was significantly greater in study group than control group (p<0.001), Reduction in hemoglobin levels ware significantly less in study group than control group (p<0.001). There was nonsignificant difference between study and control groups as regards to preoperative hematocrite (p=0.967), Postoperative hematocrite levels were significantly higher in study group than control group (p0.015), Reduction in hematocrite levels ware significantly less in study group than control group (p<0.001).

Article Details

Efficacy of Intravenous Tranexamic Acid in Reducing Blood Loss after Elective Cesarean Section

Authors:

Ali , Samir Abd Allah | Oof , Tamer Fares | Elmolla , Mohamed Fouad

Publisher:

Pan Arab League of Continuous Medical Education

Main Topics:

Medicine

Journal:

The Egyptian Journal of Hospital Medicine 2019 Vol.74 Issue 6, pp.1353-1358

Document Type:

Article

Publication Date:

1/2019

Document Language:

English

Document ID (Org No.):

136839

Frequency:

Quarterly

eISSN:

20907125

pISSN:

16872002

Descriptors:

CAESAREAN SECTION

BIRTH

SURGICAL OPERATIONS

PREGNANT WOMEN

EGYPT

Cesarean Section

Lower Segment Cesarean Section

Issues

Article Details

Authors: Ali , Samir Abd Allah | Oof , Tamer Fares | Elmolla , Mohamed Fouad

Publisher: Pan Arab League of Continuous Medical Education

Main Topics: Medicine

Journal: The Egyptian Journal of Hospital Medicine 2019 Vol.74 Issue 6, pp.1353-1358

Document Type: Article

Publication Date: 1/2019

Document Language: English

Document ID (Org No.): 136839

Frequency: Quarterly

eISSN: 20907125

pISSN: 16872002

Descriptors:

Issues

Authors:

Ali , Samir Abd Allah | Oof , Tamer Fares | Elmolla , Mohamed Fouad

Publisher:

Pan Arab League of Continuous Medical Education

Main Topics:

Medicine

Journal:

The Egyptian Journal of Hospital Medicine 2019 Vol.74 Issue 6, pp.1353-1358

Document Type:

Article

Publication Date:

1/2019

Document Language:

English

Document ID (Org No.):

136839

Frequency:

Quarterly

eISSN:

20907125

pISSN:

16872002