Empty Follicle Syndrome : The Possible Cause of Occurrence

Tahereh Madani; Nadia Jahangiri

doi:10.5001/omj.2015.83

Article Details

Empty Follicle Syndrome : The Possible Cause of Occurrence

Authors:

Tahereh Madani | Nadia Jahangiri

Publisher:

Oman Medical Specialty Board

Main Topics:

Medicine

Journal:

Oman Medical Journal 2015 Vol.30 Issue 6, pp.417-420

Document Type:

Article

Publication Date:

11/2015

Document Language:

English

Document ID (Org No.):

73448

Frequency:

Bi-Monthly

eISSN:

20705204

pISSN:

1999768X

DOI:

10.5001/omj.2015.83

Descriptors:

Keywords:

Abstract:

 Objectives: Empty follicle syndrome (EFS), although rare, is a disappointing condition inwhich no oocytes are retrieved from mature follicle after ovulation induction in in vitrofertilization (IVF) cycles. The aim of this study was to estimate the incidence and factorsassociated with EFS. Methods: All cycles resulting in EFS from May 2012 to September2013 were retrospectively identified at a tertiary referral infertility center. Among the 3,356cycles performed, 58 (1.7%) women who underwent their first IVF cycle and had no oocyteretrieval were enrolled in the study. Three different stimulation protocols (long, antagonist,and miniflare) were mainly used for induction of follicular growth. Data relating to theage, follicle stimulating hormone (FSH) level, anti-Müllerain hormone (AMH) level,and the number of ampules and follicles for each patient was obtained. Results: Out of58 individuals, 10 (17.2%) showed false type and 48 (82.8%) showed genuine EFS. Themost frequent findings in our study were diminished ovarian reserve, low anti-Müllerianhormone (AMH; ≤0.5 ng/mL), and less than four mature follicles, indicating EFS in 1.7%of the patients. Conclusion: Low serum AMH levels and a small number of follicles afterovarian stimulation is the manifestation of diminished ovarian reserve. Thus, we suggestthat EFS could be a manifestation of low ovarian reserve.

Article Details

Empty Follicle Syndrome : The Possible Cause of Occurrence

Authors:

Tahereh Madani | Nadia Jahangiri

Publisher:

Oman Medical Specialty Board

Main Topics:

Medicine

Journal:

Oman Medical Journal 2015 Vol.30 Issue 6, pp.417-420

Document Type:

Article

Publication Date:

11/2015

Document Language:

English

Document ID (Org No.):

73448

Frequency:

Bi-Monthly

eISSN:

20705204

pISSN:

1999768X

DOI:

10.5001/omj.2015.83

Descriptors:

MEDICAL SCIENCES

OVARIAN DISEASES

INDUCED OVULATION

REPRODUCTION CONTROL

IN VITRO FERTILIZATION

DIAGNOSIS

PATIENTS

Oocyte Retrieval

Ovulation Induction

Ovarian Reserve

Fertilization in Vitro

Issues

Article Details

Authors: Tahereh Madani | Nadia Jahangiri

Publisher: Oman Medical Specialty Board

Main Topics: Medicine

Journal: Oman Medical Journal 2015 Vol.30 Issue 6, pp.417-420

Document Type: Article

Publication Date: 11/2015

Document Language: English

Document ID (Org No.): 73448

Frequency: Bi-Monthly

eISSN: 20705204

pISSN: 1999768X

DOI: 10.5001/omj.2015.83

Descriptors:

Issues

Authors:

Tahereh Madani | Nadia Jahangiri

Publisher:

Oman Medical Specialty Board

Main Topics:

Medicine

Journal:

Oman Medical Journal 2015 Vol.30 Issue 6, pp.417-420

Document Type:

Article

Publication Date:

11/2015

Document Language:

English

Document ID (Org No.):

73448

Frequency:

Bi-Monthly

eISSN:

20705204

pISSN:

1999768X

DOI:

10.5001/omj.2015.83