BK virus associated nephropathy after renal transplantation: a single center experience

Barış ESER; Özlem YAYAR; Mustafa ŞAHİN; Ünsal SAVCI; Başol CANBAKAN; Mehmet Deniz AYLI

doi:https://doi.org/10.21601/ortadogutipdergisi.376965

Article Details

BK virus associated nephropathy after renal transplantation: a single center experience

Authors:

Barış ESER | Özlem YAYAR | Mustafa ŞAHİN | Ünsal SAVCI | Başol CANBAKAN | Mehmet Deniz AYLI

Publisher:

MEDİTAGEM Ltd. Şti.

Main Topics:

Promotion of health

Journal:

Ortadogu Medical Journal 2018 Vol.10 Issue 3, pp.234-239

Document Type:

Article

Publication Date:

9/2018

Document Language:

English

Document ID (Org No.):

2000768038

Frequency:

Quarterly

eISSN:

2548-0251

DOI:

https://doi.org/10.21601/ortadogutipdergisi.376965

Keywords:

Abstract:

 


Aim:
BK virus (BKV) nephropathy is an important cause of
allograft failure in renal transplant recipients that is linked to highly
potent immunosuppressive therapy. The risk factors associated BKV viremia and BKV
associated nephropathy (BKVN) and
response to therapy were also evaluated in this study.


Material and Method: We retrospectively analyzed 107 renal
transplant patients from cadaveric or living related donors between 2008 and
2014. After
transplantation, we performed BKV polymerase chain reaction (PCR) assay screening for the
presence of viremia in all patients.
Peripheral blood samples were collected for screening monthly for first three
months, after then every three months until the end of the first transplant
year. BKV DNA copies were
measured by real time PCR. Allograft biopsies were performed in the presence of
clinical indication. All biopsies were analyzed according to Banff criteria and
evaluated for the presence of BKVN.





 


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Article Details

BK virus associated nephropathy after renal transplantation: a single center experience

Authors:

Barış ESER | Özlem YAYAR | Mustafa ŞAHİN | Ünsal SAVCI | Başol CANBAKAN | Mehmet Deniz AYLI

Publisher:

MEDİTAGEM Ltd. Şti.

Main Topics:

Promotion of health

Journal:

Ortadogu Medical Journal 2018 Vol.10 Issue 3, pp.234-239

Document Type:

Article

Publication Date:

9/2018

Document Language:

English

Document ID (Org No.):

2000768038

Frequency:

Quarterly

eISSN:

2548-0251

DOI:

https://doi.org/10.21601/ortadogutipdergisi.376965

BK virüsü

renal transplantasyon

nefropati

Issues

Article Details

BK virus associated nephropathy after renal transplantation: a single center experience

Authors: Barış ESER | Özlem YAYAR | Mustafa ŞAHİN | Ünsal SAVCI | Başol CANBAKAN | Mehmet Deniz AYLI

Publisher: MEDİTAGEM Ltd. Şti.

Main Topics: Promotion of health

Journal: Ortadogu Medical Journal 2018 Vol.10 Issue 3, pp.234-239

Document Type: Article

Publication Date: 9/2018

Document Language: English

Document ID (Org No.): 2000768038

Frequency: Quarterly

eISSN: 2548-0251

DOI: https://doi.org/10.21601/ortadogutipdergisi.376965

BK virüsü

renal transplantasyon

nefropati

Issues

Authors:

Barış ESER | Özlem YAYAR | Mustafa ŞAHİN | Ünsal SAVCI | Başol CANBAKAN | Mehmet Deniz AYLI

Publisher:

MEDİTAGEM Ltd. Şti.

Main Topics:

Promotion of health

Journal:

Ortadogu Medical Journal 2018 Vol.10 Issue 3, pp.234-239

Document Type:

Article

Publication Date:

9/2018

Document Language:

English

Document ID (Org No.):

2000768038

Frequency:

Quarterly

eISSN:

2548-0251

DOI:

https://doi.org/10.21601/ortadogutipdergisi.376965