Is There Any Relationship Between Circulating Serum 25-Hydroxyvitamin D Level and Presence of Helicobacter Pylori As Well As Gastric Inflammation Severity?

Tarik AKAR

doi:https://doi.org/10.5455/umj.20190227101537

Article Details

Is There Any Relationship Between Circulating Serum 25-Hydroxyvitamin D Level and Presence of Helicobacter Pylori As Well As Gastric Inflammation Severity?

Authors:

Tarik AKAR

Publisher:

Kemal Türker ULUTAŞ

Journal:

The Ulutas Medical Journal 2019 Vol.5 Issue 1, pp.84-90

Document Type:

Article

Publication Date:

12/2018

Document Language:

English

Document ID (Org No.):

2000802745

Frequency:

Quarterly

eISSN:

2149-388X

pISSN:

2149-0430

DOI:

https://doi.org/10.5455/umj.20190227101537

Abstract:

 

Background: Helicobacter Pylori  H. Pylori  and ongoing chronic gastric inflammation are the most crucial factors leading to gastric cancer. The serum 25 Hydroxyvitamin D is the fundamental keys to the proper functioning of the immune system and reduction of inflammation. The primary aim of this study is to evaluate the association between the serum level of 25 Hydroxyvitamin D and the presence of H. Pylori as well as gastric inflammation.  Materials and Methods: A total of 91  18-85 years old  dyspeptic patients having a standard laboratory parameter  hematologic, liver and kidney  without chronic medical problems and were enrolled in this study. During an upper endoscopy, at least four stomach biopsies were taken and evaluated according to Sydney classification. The serum 25-Hydroxyvitamin D level was also calculated at the same time endoscopy.  Results: In population, 48  52.7%  were H. Pylori positive, while 41  47.3%  were H. Pylori negative. The mean age, gender, hemoglobin, mean corpuscular volume, mean platelet volume, CRP, ferritin, red cell distribution width, endoscopic findings, and iron were similar in two groups  p0.05 . The serum 25-Hydroxyvitamin D levels were similar in groups of H. Pylori positive and negative.    Conclusion: This is the first study investigating the relationship between the serum 25-Hydroxyvitamin D level and H. Pylori as well as gastric inflammation sub-groups. Consequently, we found no relationship between serum 25 Hydroxyvitamin D level and H. Pylori as well as gastric inflammation severity.

Article Details

Is There Any Relationship Between Circulating Serum 25-Hydroxyvitamin D Level and Presence of Helicobacter Pylori As Well As Gastric Inflammation Severity?

Authors: Tarik AKAR

Publisher: Kemal Türker ULUTAŞ

Journal: The Ulutas Medical Journal 2019 Vol.5 Issue 1, pp.84-90

Document Type: Article

Publication Date: 12/2018

Document Language: English

Document ID (Org No.): 2000802745

Frequency: Quarterly

eISSN: 2149-388X

pISSN: 2149-0430

DOI: https://doi.org/10.5455/umj.20190227101537

Issues

Authors:

Tarik AKAR

Publisher:

Kemal Türker ULUTAŞ

Journal:

The Ulutas Medical Journal 2019 Vol.5 Issue 1, pp.84-90

Document Type:

Article

Publication Date:

12/2018

Document Language:

English

Document ID (Org No.):

2000802745

Frequency:

Quarterly

eISSN:

2149-388X

pISSN:

2149-0430

DOI:

https://doi.org/10.5455/umj.20190227101537