Is Submucosal Lipomatosis of the Appendix Vermiformis Really a Rare Entity?

Gizem Ay Haldız

Article Details

Is Submucosal Lipomatosis of the Appendix Vermiformis Really a Rare Entity?

Authors:

Gizem Ay Haldız

Publisher:

Harran University

Main Topics:

Genel Cerrahi | Patoloji | Çocuk Cerrahisi

Journal:

Harran Üniversitesi Tıp Fakültesi Dergisi Vol.21 Issue 1, pp.42-48

Document Type:

Article

Publication Date:

4/2024

Document Language:

English

Document ID (Org No.):

2001313098

pISSN:

1304-9623

Keywords:

Abstract:

 Background: Acute appendicitis AA is the most common surgical emergency in patients who visit the emergency department with abdominal pain. In some of the patients who were operated with a prediagnosis of AA, lymphoid hyperplasia, fecalitis, enterobius vermicularis, carcinoid tumor, or adenoma are determined without transmural inflammation in microscopic examination of the appendix. Submucosal lipomatosis is also another entity that has been rarely reported in appendix localization. In this study, we aimed to determine the frequency and severity of submucosal fatty tissue SFT in appendectomy specimens and identify risk factors. Materials and Methods: 293 appendectomy specimens were evaluated retrospectively. The amounts of SFT A0: None, A1: Isolated adipocytes Mild, A2: Small adipocyte groups Moderate, A3: Prominent adipocyte groups Marked, A4: Severe adipocyte groups that narrow the lumen Severe and the groups that were created according to the amounts of SFT Group 1: Cases with A1,2,3,4, group 2: Cases with A2,3,4, group 3: Cases with A3,4 were determined in hematoxylin-eosin sections. Results: 91.47 of the cases had any amount of SFT. Amounts of SFT were mild in 23.89, moderate in 46.76, marked in 18.09, and severe in 2.73. All of the cases without SFT were in pediatric age. When the amount of SFT increased, the mean age and adult rate increased regularly p0.05. As 68 of the cases without SFT were female, male predominance was observed in cases with SFT. When the amount of SFT increased, male rate increased regularly p0.05. AA wasnt determined in 26,28 of the cases. The AA rate in the group without SFT 20 was marked lower than group 1 78,73, group 2 82,32, and group 3 83,87 p0.05. The most prominent increase in AA rate was between the group without SFT and group 1 which was the most sensitive group to the amount of SFT. When group 1,2,3 were compared, no significant increase in the AA ratio was found. Conclusions: The presence of SFT in the appendix is a common condition. Age increase and male gender are risk factors for the accumulation of SFT. Due to SFT accumulation increases the risk of AA, it would be logical to classify it as mildmoderatemarkedsevere, and accept it as Submucosal lipomatosis.

 Background: Acute appendicitis AA is the most common surgical emergency in patients who visit the emergency department with abdominal pain. In some of the patients who were operated with a prediagnosis of AA, lymphoid hyperplasia, fecalitis, enterobius vermicularis, carcinoid tumor, or adenoma are determined without transmural inflammation in microscopic examination of the appendix. Submucosal lipomatosis is also another entity that has been rarely reported in appendix localization. In this study, we aimed to determine the frequency and severity of submucosal fatty tissue SFT in appendectomy specimens and identify risk factors. Materials and Methods: 293 appendectomy specimens were evaluated retrospectively. The amounts of SFT A0: None, A1: Isolated adipocytes Mild, A2: Small adipocyte groups Moderate, A3: Prominent adipocyte groups Marked, A4: Severe adipocyte groups that narrow the lumen Severe and the groups that were created according to the amounts of SFT Group 1: Cases with A1,2,3,4, group 2: Cases with A2,3,4, group 3: Cases with A3,4 were determined in hematoxylin-eosin sections. Results: 91.47 of the cases had any amount of SFT. Amounts of SFT were mild in 23.89, moderate in 46.76, marked in 18.09, and severe in 2.73. All of the cases without SFT were in pediatric age. When the amount of SFT increased, the mean age and adult rate increased regularly p0.05. As 68 of the cases without SFT were female, male predominance was observed in cases with SFT. When the amount of SFT increased, male rate increased regularly p0.05. AA wasnt determined in 26,28 of the cases. The AA rate in the group without SFT 20 was marked lower than group 1 78,73, group 2 82,32, and group 3 83,87 p0.05. The most prominent increase in AA rate was between the group without SFT and group 1 which was the most sensitive group to the amount of SFT. When group 1,2,3 were compared, no significant increase in the AA ratio was found. Conclusions: The presence of SFT in the appendix is a common condition. Age increase and male gender are risk factors for the accumulation of SFT. Due to SFT accumulation increases the risk of AA, it would be logical to classify it as mildmoderatemarkedsevere, and accept it as Submucosal lipomatosis.

 Background: Acute appendicitis AA is the most common surgical emergency in patients who visit the emergency department with abdominal pain. In some of the patients who were operated with a prediagnosis of AA, lymphoid hyperplasia, fecalitis, enterobius vermicularis, carcinoid tumor, or adenoma are determined without transmural inflammation in microscopic examination of the appendix. Submucosal lipomatosis is also another entity that has been rarely reported in appendix localization. In this study, we aimed to determine the frequency and severity of submucosal fatty tissue SFT in appendectomy specimens and identify risk factors. Materials and Methods: 293 appendectomy specimens were evaluated retrospectively. The amounts of SFT A0: None, A1: Isolated adipocytes Mild, A2: Small adipocyte groups Moderate, A3: Prominent adipocyte groups Marked, A4: Severe adipocyte groups that narrow the lumen Severe and the groups that were created according to the amounts of SFT Group 1: Cases with A1,2,3,4, group 2: Cases with A2,3,4, group 3: Cases with A3,4 were determined in hematoxylin-eosin sections. Results: 91.47 of the cases had any amount of SFT. Amounts of SFT were mild in 23.89, moderate in 46.76, marked in 18.09, and severe in 2.73. All of the cases without SFT were in pediatric age. When the amount of SFT increased, the mean age and adult rate increased regularly p0.05. As 68 of the cases without SFT were female, male predominance was observed in cases with SFT. When the amount of SFT increased, male rate increased regularly p0.05. AA wasnt determined in 26,28 of the cases. The AA rate in the group without SFT 20 was marked lower than group 1 78,73, group 2 82,32, and group 3 83,87 p0.05. The most prominent increase in AA rate was between the group without SFT and group 1 which was the most sensitive group to the amount of SFT. When group 1,2,3 were compared, no significant increase in the AA ratio was found. Conclusions: The presence of SFT in the appendix is a common condition. Age increase and male gender are risk factors for the accumulation of SFT. Due to SFT accumulation increases the risk of AA, it would be logical to classify it as mildmoderatemarkedsevere, and accept it as Submucosal lipomatosis.

 Amaç: Akut apandisit AA karın ağrısı ile acil servise başvuran hastalarda en sık saptanan cerrahi acildir. AA ön tanısı ile opere edilen hastaların bir kısmında apendiksin mikroskobik incelemesinde transmural inflamasyon eşlik etmeksizin lenfoid hiperplazi, fekalit, enterobius vermikularis, karsionid tümör veya adenom saptanır. Submukozal lipomatoziste apendikste nadiren bildirilen bir diğer antitedir. Bu çalışmada apendektomi spesmenlerinde submukozal yağlı doku SYD varlığının sıklığını ve şiddetini belirlemeyi, risk faktörlerini tanımlamayı amaçladık. Materyal ve Metod: 293 apendektomi spesmeni retrospektif olarak incelenmiştir. Hematoksilen-eozin kesitlerde SYD miktarları M0: Yok, M1: İzole adipositler Hafif, M2: Küçük adiposit grupları Orta, M3: Belirgin adiposit grupları Belirgin, M4: Lümeni daraltan adiposit grupları Şiddetli ve SYD miktarlarına göre oluşturulan gruplar Grup 1: M1,2,3,4 olan olgular, grup 2: M2,3,4 olan olgular, grup 3: M3,4 olan olgular belirlenmiştir. Bulgular: Olguların 91,47sinde değişik miktarlarda SYD mevcuttur. SYD miktarları olguların 23,89unda hafif, 46,76sında orta, 18,09unda belirgin, 2,73ünde şiddetlidir. SYD içermeyen olguların tamamı pediatrik yaş grubundadır. SYD miktarı arttıkça yaş ortalamaları ve yetişkin oranları düzenli olarak artmıştır p0,05. SYD içermeyen olguların 68i kadınken, SYD içeren olgularda erkek hakimiyeti görülmüştür. SYD miktarı arttıkça erkek oranları düzenli olarak artmıştır p0,05. Olguların 26,28inde AA saptanmamıştır. AA oranları SYD içermeyen grupta 20, grup 1 78,73, grup 2 82,32 ve grup 3e 83,87 göre belirgin düşüktür p0.05. AA oranında en belirgin artış SYD içermeyen grup ile SYD miktarına en hassas olan grup 1 arasındadır. Grup 1,2,3 karşılaştırıldığında AA oranlarında anlamlı artış belirlenememiştir. Sonuç: Apendikste SYD varlığı sık görülen bir durumdur. Yaş artışı ve erkek cinsiyet SYD birikimi için risk faktörüdür. SYD birikiminin AA riskini arttırması sebebiyle hafifortabelirginşiddetli olarak sınıflandırılarak Submukozal lipomatozis kabul edilmesi mantıklı olacaktır.

Article Details

Is Submucosal Lipomatosis of the Appendix Vermiformis Really a Rare Entity?

Authors:

Gizem Ay Haldız

Publisher:

Harran University

Main Topics:

Genel Cerrahi | Patoloji | Çocuk Cerrahisi

Journal:

Harran Üniversitesi Tıp Fakültesi Dergisi Vol.21 Issue 1, pp.42-48

Document Type:

Article

Publication Date:

4/2024

Document Language:

English

Document ID (Org No.):

2001313098

pISSN:

1304-9623

Appendicitis

appendix

lipomatosis.Apandisit

apendiks

lipomatozis.

Issues

Article Details

Is Submucosal Lipomatosis of the Appendix Vermiformis Really a Rare Entity?

Authors: Gizem Ay Haldız

Publisher: Harran University

Main Topics: Genel Cerrahi | Patoloji | Çocuk Cerrahisi

Journal: Harran Üniversitesi Tıp Fakültesi Dergisi Vol.21 Issue 1, pp.42-48

Document Type: Article

Publication Date: 4/2024

Document Language: English

Document ID (Org No.): 2001313098

pISSN: 1304-9623

Appendicitis

appendix

lipomatosis.Apandisit

apendiks

lipomatozis.

Issues

Authors:

Gizem Ay Haldız

Publisher:

Harran University

Main Topics:

Genel Cerrahi | Patoloji | Çocuk Cerrahisi

Journal:

Harran Üniversitesi Tıp Fakültesi Dergisi Vol.21 Issue 1, pp.42-48

Document Type:

Article

Publication Date:

4/2024

Document Language:

English

Document ID (Org No.):

2001313098

pISSN:

1304-9623