Antipsychotic Exposures in an Emergency Department

M. Aylin ARICI; Aynur ŞAHİN; Neşe Çolak ORAY; Başak BAYRAM; Yeşim TUNÇOK

doi:https://doi.org/10.5152/jbachs.2017.121

Article Details

Antipsychotic Exposures in an Emergency Department

Authors:

M. Aylin ARICI | Aynur ŞAHİN | Neşe Çolak ORAY | Başak BAYRAM | Yeşim TUNÇOK

Publisher:

Dokuz Eylul University

Journal:

Journal of Basic and Clinical Health Sciences 2017 Vol.1 Issue 2, pp.41-46

Document Type:

Article

Publication Date:

5/2017

Document Language:

English

Document ID (Org No.):

2000493743

Frequency:

Tri-annual

eISSN:

2564-7288

DOI:

https://doi.org/10.5152/jbachs.2017.121

Abstract:

 

Purpose: We analyzed the antipsychotic medication exposures’ distribution in typical and atypical antipsychotic exposures and severity of the clinical signs and symptoms admitted to the Department of Emergency Medicine at Dokuz Eylul University  EMDEU  between 1993 and 2015.Methods: Demographics of patients, type of exposure, distribution according to the reason, the amount of the exposed antipsychotics, clinical findings, the length of hospital stay, and the outcome of the patients in typical and atypical antipsychotic exposures were analyzed.Results: Among all of the adult poisonings in EMDEU, 2.6% of them were due to exposure to antipsychotic medication. Most of the antipsychotic exposures were intentional  95.5% . Most antipsychotics exposed were atypical antipsychotics  77.3% . Frequently exposed atypical and typical antipsychotics were quetiapine  52.9%  and chlorpromazine  26.7% , respectively. 46.7% of typical antipsychotics and 35.3% of atypical antipsychotics were in toxic doses. Tachycardia  39.4%  was the most common symptom in typical  40.0%  and atypical  39.2%  antipsychotic exposures. Atypical antipsychotic exposure did not cause fewer clinical findings than that of typical antipsychotics. Gastric decontamination was applied to 56.1% of the patients. All of the patients exposed to antipsychotics recovered.Conclusion: Because of the widespread use of atypical antipsychotics, we observed atypical antipsychotic exposures more than typical antipsychotic exposures. Although mild and moderate clinical findings are common in both typical and atypical antipsychotic exposures, serious clinical findings can be observed in all intoxications. Therefore, all patients poisoned with typical or atypical antipsychotic toxic doses should be closely monitored in the emergency department.

Article Details

Antipsychotic Exposures in an Emergency Department

Authors: M. Aylin ARICI | Aynur ŞAHİN | Neşe Çolak ORAY | Başak BAYRAM | Yeşim TUNÇOK

Publisher: Dokuz Eylul University

Journal: Journal of Basic and Clinical Health Sciences 2017 Vol.1 Issue 2, pp.41-46

Document Type: Article

Publication Date: 5/2017

Document Language: English

Document ID (Org No.): 2000493743

Frequency: Tri-annual

eISSN: 2564-7288

DOI: https://doi.org/10.5152/jbachs.2017.121

Issues

Authors:

M. Aylin ARICI | Aynur ŞAHİN | Neşe Çolak ORAY | Başak BAYRAM | Yeşim TUNÇOK

Publisher:

Dokuz Eylul University

Journal:

Journal of Basic and Clinical Health Sciences 2017 Vol.1 Issue 2, pp.41-46

Document Type:

Article

Publication Date:

5/2017

Document Language:

English

Document ID (Org No.):

2000493743

Frequency:

Tri-annual

eISSN:

2564-7288

DOI:

https://doi.org/10.5152/jbachs.2017.121