The utility of EBUS-TBNA in mediastinal or hilar lymph node evaluation in extrapulmonary malignancy

Onur Fevzi ERER; Ceyda ANAR; Serhat EROL; Serir ÖZKAN

Article Details

The utility of EBUS-TBNA in mediastinal or hilar lymph node evaluation in extrapulmonary malignancy

Authors:

Onur Fevzi ERER | Ceyda ANAR | Serhat EROL | Serir ÖZKAN

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 1, pp.112-119

Document Type:

Article

Publication Date:

1/2016

Document Language:

Turkish

Document ID (Org No.):

2000752321

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Abstract:

 

Background/aim: The aim of this study was to determine the diagnostic performance of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in the diagnosis of mediastinal and hilar lymph nodes (LNs) in patients with known extrapulmonary malignancy.  Materials and methods: Between March 2011 and August 2013, 378 EBUS-TBNA procedures were performed. Sixty-three (16.6%) of these were performed on known extrapulmonary malignancy patients.   Results: There were 28 male and 35 female patients, with median ages of 65 years (min-max: 53-87) and 57 years (min-max: 39-76), respectively. From the 63 cases, 138 lymph nodes (LNs) were sampled with EBUS-TBNA (median: 2 LNs/patient; min-max: 1-4). Results of EBUS-TBNA revealed malignancy in 18 (28.5%) and nonmalignancy in 45 (71.5%). In the nonmalignant group, there were false negatives in 5 (7.9%), anthracosis in 13 (20.6%), reactive adenitis in 16 (25.3%), sarcoidosis in 7 (11.1%), and tuberculosis in 2 (3.1%), and 2 were not evaluated (lost to follow-up) (3.1%). The diagnostic sensitivity, accuracy, and negative predictive value of EBUS-TBNA per patient were 78.2%, 91.8%, and 88.3%, respectively.   Conclusion: EBUS-TBNA is a safe, minimally invasive, and effective method and can be considered as the initial test for the histopathological diagnosis of mediastinal and hilar lymphadenopathy in patients with extrapulmonary malignancy.

Article Details

The utility of EBUS-TBNA in mediastinal or hilar lymph node evaluation in extrapulmonary malignancy

Authors: Onur Fevzi ERER | Ceyda ANAR | Serhat EROL | Serir ÖZKAN

Publisher: TUBITAK

Journal: Turkish Journal of Medical Sciences 2016 Vol.46 Issue 1, pp.112-119

Document Type: Article

Publication Date: 1/2016

Document Language: Turkish

Document ID (Org No.): 2000752321

Frequency: Bimonthly

eISSN: 1303-6165

pISSN: 1300-0144

Issues

Authors:

Onur Fevzi ERER | Ceyda ANAR | Serhat EROL | Serir ÖZKAN

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 1, pp.112-119

Document Type:

Article

Publication Date:

1/2016

Document Language:

Turkish

Document ID (Org No.):

2000752321

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144