Diagnostic performance between RT-PCR and chest CT in outpatients with clinically suspected COVID-19

Elif Tükenmez Tigen; Buket Erturk Sengel; Canan Cimsit; Çiğdem Apaydın Kaya; Volkan Korten

Article Details

Diagnostic performance between RT-PCR and chest CT in outpatients with clinically suspected COVID-19

Authors:

Elif Tükenmez Tigen | Buket Erturk Sengel | Canan Cimsit | Çiğdem Apaydın Kaya | Volkan Korten

Publisher:

Marmara University

Main Topics:

Surgery (Other)

Journal:

Marmara Medical Journal Vol.37 Issue 1, pp.18-22

Document Type:

Article

Publication Date:

1/2024

Document Language:

English

Document ID (Org No.):

2001302662

pISSN:

1019-1941

Keywords:

Abstract:

 Objective: To investigate the diagnostic performance between chest computed tomography CT and reverse transcription-polymerase chain reaction RT-PCR in outpatients with suspected coronavirus disease 2019 COVID-19. Patients and Methods: Between March and June 2020, a total of 812 patients with clinically suspected COVID-19 who underwent both chest CT and initial-single RT-PCR on admission to outpatient units were retrospectively enrolled. CT severity-score CT-SS was calculated and data were matched with PCR results. Results: Of 812 patients, 54 439812 had positive RT-PCR results, and 47 425812 had a positive chest CT scan. With RT-PCR results as reference, the sensitivity, specificity, accuracy of chest CT in defining COVID-19 infection were 60, 95 CI 56-65, 265439 patients, 57 95 CI 52-62, 213373, 59 95 CI 55-62, 478812, respectively. Three hundred eighty-seven 47 patients had no CT findings, 380812 46.8 had mild, 45812 5.5 had moderate, and no patients in the severe group Conclusion: Chest CT did not show high sensitivity for the diagnosis of COVID-19 for outpatients. We suggest RT-PCR should be the primary diagnostic tool. Chest CT might be considered if there is a strong clinical suspicion with repeatedly negative RT-PCR test results, ensuring infection prevention and control measures can be preserved.

 Objective: To investigate the diagnostic performance between chest computed tomography CT and reverse transcription-polymerase chain reaction RT-PCR in outpatients with suspected coronavirus disease 2019 COVID-19. Patients and Methods: Between March and June 2020, a total of 812 patients with clinically suspected COVID-19 who underwent both chest CT and initial-single RT-PCR on admission to outpatient units were retrospectively enrolled. CT severity-score CT-SS was calculated and data were matched with PCR results. Results: Of 812 patients, 54 439812 had positive RT-PCR results, and 47 425812 had a positive chest CT scan. With RT-PCR results as reference, the sensitivity, specificity, accuracy of chest CT in defining COVID-19 infection were 60, 95 CI 56-65, 265439 patients, 57 95 CI 52-62, 213373, 59 95 CI 55-62, 478812, respectively. Three hundred eighty-seven 47 patients had no CT findings, 380812 46.8 had mild, 45812 5.5 had moderate, and no patients in the severe group Conclusion: Chest CT did not show high sensitivity for the diagnosis of COVID-19 for outpatients. We suggest RT-PCR should be the primary diagnostic tool. Chest CT might be considered if there is a strong clinical suspicion with repeatedly negative RT-PCR test results, ensuring infection prevention and control measures can be preserved.

 Objective: To investigate the diagnostic performance between chest computed tomography CT and reverse transcription-polymerase chain reaction RT-PCR in outpatients with suspected coronavirus disease 2019 COVID-19. Patients and Methods: Between March and June 2020, a total of 812 patients with clinically suspected COVID-19 who underwent both chest CT and initial-single RT-PCR on admission to outpatient units were retrospectively enrolled. CT severity-score CT-SS was calculated and data were matched with PCR results. Results: Of 812 patients, 54 439812 had positive RT-PCR results, and 47 425812 had a positive chest CT scan. With RT-PCR results as reference, the sensitivity, specificity, accuracy of chest CT in defining COVID-19 infection were 60, 95 CI 56-65, 265439 patients, 57 95 CI 52-62, 213373, 59 95 CI 55-62, 478812, respectively. Three hundred eighty-seven 47 patients had no CT findings, 380812 46.8 had mild, 45812 5.5 had moderate, and no patients in the severe group Conclusion: Chest CT did not show high sensitivity for the diagnosis of COVID-19 for outpatients. We suggest RT-PCR should be the primary diagnostic tool. Chest CT might be considered if there is a strong clinical suspicion with repeatedly negative RT-PCR test results, ensuring infection prevention and control measures can be preserved.

 Objective: To investigate the diagnostic performance between chest computed tomography CT and reverse transcription-polymerase chain reaction RT-PCR in outpatients with suspected coronavirus disease 2019 COVID-19. Patients and Methods: Between March and June 2020, a total of 812 patients with clinically suspected COVID-19 who underwent both chest CT and initial-single RT-PCR on admission to outpatient units were retrospectively enrolled. CT severity-score CT-SS was calculated and data were matched with PCR results. Results: Of 812 patients, 54 439812 had positive RT-PCR results, and 47 425812 had a positive chest CT scan. With RT-PCR results as reference, the sensitivity, specificity, accuracy of chest CT in defining COVID-19 infection were 60, 95 CI 56-65, 265439 patients, 57 95 CI 52-62, 213373, 59 95 CI 55-62, 478812, respectively. Three hundred eighty-seven 47 patients had no CT findings, 380812 46.8 had mild, 45812 5.5 had moderate, and no patients in the severe group Conclusion: Chest CT did not show high sensitivity for the diagnosis of COVID-19 for outpatients. We suggest RT-PCR should be the primary diagnostic tool. Chest CT might be considered if there is a strong clinical suspicion with repeatedly negative RT-PCR test results, ensuring infection prevention and control measures can be preserved.

Article Details

Diagnostic performance between RT-PCR and chest CT in outpatients with clinically suspected COVID-19

Authors:

Elif Tükenmez Tigen | Buket Erturk Sengel | Canan Cimsit | Çiğdem Apaydın Kaya | Volkan Korten

Publisher:

Marmara University

Main Topics:

Surgery (Other)

Journal:

Marmara Medical Journal Vol.37 Issue 1, pp.18-22

Document Type:

Article

Publication Date:

1/2024

Document Language:

English

Document ID (Org No.):

2001302662

pISSN:

1019-1941

Chest CT

RT-PCR

COVID-19

Outpatient

Diagnosis

Issues

Article Details

Diagnostic performance between RT-PCR and chest CT in outpatients with clinically suspected COVID-19

Authors: Elif Tükenmez Tigen | Buket Erturk Sengel | Canan Cimsit | Çiğdem Apaydın Kaya | Volkan Korten

Publisher: Marmara University

Main Topics: Surgery (Other)

Journal: Marmara Medical Journal Vol.37 Issue 1, pp.18-22

Document Type: Article

Publication Date: 1/2024

Document Language: English

Document ID (Org No.): 2001302662

pISSN: 1019-1941

Chest CT

RT-PCR

COVID-19

Outpatient

Diagnosis

Issues

Authors:

Elif Tükenmez Tigen | Buket Erturk Sengel | Canan Cimsit | Çiğdem Apaydın Kaya | Volkan Korten

Publisher:

Marmara University

Main Topics:

Surgery (Other)

Journal:

Marmara Medical Journal Vol.37 Issue 1, pp.18-22

Document Type:

Article

Publication Date:

1/2024

Document Language:

English

Document ID (Org No.):

2001302662

pISSN:

1019-1941