Obstructive sleep apnea syndrome (OSAS) related hypertension: A review of pathophysiology and potential therapeutic approaches

Ayşegül NAVDAR

doi:https://doi.org/10.28982/josam.727915

Article Details

Obstructive sleep apnea syndrome (OSAS) related hypertension: A review of pathophysiology and potential therapeutic approaches

Authors:

Ayşegül NAVDAR

Publisher:

Fatih BAŞAK

Main Topics:

Diseases

Journal:

Journal of Surgery and Medicine 2020 Vol.4 Issue 5, pp.410-413

Document Type:

Article

Publication Date:

4/2020

Document Language:

English

Document ID (Org No.):

2000499922

Frequency:

Monthly

eISSN:

2602-2079

DOI:

https://doi.org/10.28982/josam.727915

Abstract:

 

Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder related with cardiovascular diseases, including hypertension. There are lots of evidence supporting the relationship between OSAS and hypertension, modulated by multiple factors, but the exact mechanisms underlying this complex cause and effect relationship remain unclear. The alternating pattern of OSAS-related hypertension is closely related with target organ damage, especially in the heart and brain. In this review, the etiological factors, clinical types, probable pathophysiologic mechanisms, diagnostic methods, and current therapeutic approaches to OSAS-related hypertension is discussed in the light of current literature.

 


Obstruktif uyku apne sendromu (OUAS), hipertansiyon da dahil olmak üzere kardiyovasküler hastalıklarla ilişkisi olan yaygın bir uyku bozukluğudur. OUAS ve hipertansiyon arasındaki ilişkiyi destekleyen birçok kanıt mevcuttur; ancak bu kompleks sebep-sonuç etkileşiminin altında yatan kesin mekanizma halen net değildir. OUAS ile alakalı hipertansiyonun değişken yapısı, kalp ve beyinin de dahil olduğu hedef organ hasarı ile yakından ilişkilidir. Bu derlemede, OUAS ile ilişkili hipertansiyonun etyolojik faktörleri, klinik tipleri, olası patofizyolojik mekanizmaları, tanı yöntemleri ve güncel tedavi yaklaşımları güncel literatür ışığında tartışılmıştır. 

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Article Details

Obstructive sleep apnea syndrome (OSAS) related hypertension: A review of pathophysiology and potential therapeutic approaches

Authors: Ayşegül NAVDAR

Publisher: Fatih BAŞAK

Main Topics: Diseases

Journal: Journal of Surgery and Medicine 2020 Vol.4 Issue 5, pp.410-413

Document Type: Article

Publication Date: 4/2020

Document Language: English

Document ID (Org No.): 2000499922

Frequency: Monthly

eISSN: 2602-2079

DOI: https://doi.org/10.28982/josam.727915

Issues

Authors:

Ayşegül NAVDAR

Publisher:

Fatih BAŞAK

Main Topics:

Diseases

Journal:

Journal of Surgery and Medicine 2020 Vol.4 Issue 5, pp.410-413

Document Type:

Article

Publication Date:

4/2020

Document Language:

English

Document ID (Org No.):

2000499922

Frequency:

Monthly

eISSN:

2602-2079

DOI:

https://doi.org/10.28982/josam.727915