Preparation and in Vitro Adhesive Application of Visible Light-Activated Modified Sodium Alginate

Rumeysa Tutar

Article Details

Preparation and in Vitro Adhesive Application of Visible Light-Activated Modified Sodium Alginate

Authors:

Rumeysa Tutar

Publisher:

Turkish Chemical Society

Main Topics:

Macromolecular Materials | Physical Properties of Materials | Natural Products and Bioactive Compounds | Characterisation of Biological Macromolecules

Journal:

Journal of the Turkish Chemical Society Section A: Chemistry Vol.12 Issue 2, pp.107-116

Document Type:

Article

Publication Date:

5/2025

Document Language:

English

Document ID (Org No.):

2001345110

pISSN:

2149-0120

Keywords:

Abstract:

 Materials that are responsive to visible light have been extensively used in biomedical applications, including tissue engineering. Tissue adhesives are among the most important applications of tissue engineering. In this study, different concentrations of Ruthenium Ru and sodium persulfate SPS photoinitiators 0.22, 0.55, and 110 mM were prepared. Sodium alginate Na-alginate was modified with methacrylate AlgMA to render it photoactive. Photoactive materials prepared with different ratios of photoinitiators were physically, chemically, morphologically, and mechanically tested. The results of the different analyses supported each other. RuSPS concentrations of 0.22, 0.55, and 110 mM were used to evaluate the hydrogel structures. No physical, chemical, or mechanical differences were observed between the 0.55, and 110 mM. The in vitro adhesion properties of the hydrogels increased significantly from 0.22 mM to 110 mM RuSPS. As the RuSPS concentration was increased, a significant increase in cell viability was observed. In particular, 110 mM RuSPS showed the greatest effect and created the most statistically significant difference.

 Materials that are responsive to visible light have been extensively used in biomedical applications, including tissue engineering. Tissue adhesives are among the most important applications of tissue engineering. In this study, different concentrations of Ruthenium Ru and sodium persulfate SPS photoinitiators 0.22, 0.55, and 110 mM were prepared. Sodium alginate Na-alginate was modified with methacrylate AlgMA to render it photoactive. Photoactive materials prepared with different ratios of photoinitiators were physically, chemically, morphologically, and mechanically tested. The results of the different analyses supported each other. RuSPS concentrations of 0.22, 0.55, and 110 mM were used to evaluate the hydrogel structures. No physical, chemical, or mechanical differences were observed between the 0.55, and 110 mM. The in vitro adhesion properties of the hydrogels increased significantly from 0.22 mM to 110 mM RuSPS. As the RuSPS concentration was increased, a significant increase in cell viability was observed. In particular, 110 mM RuSPS showed the greatest effect and created the most statistically significant difference.

 Materials that are responsive to visible light have been extensively used in biomedical applications, including tissue engineering. Tissue adhesives are among the most important applications of tissue engineering. In this study, different concentrations of Ruthenium Ru and sodium persulfate SPS photoinitiators 0.22, 0.55, and 110 mM were prepared. Sodium alginate Na-alginate was modified with methacrylate AlgMA to render it photoactive. Photoactive materials prepared with different ratios of photoinitiators were physically, chemically, morphologically, and mechanically tested. The results of the different analyses supported each other. RuSPS concentrations of 0.22, 0.55, and 110 mM were used to evaluate the hydrogel structures. No physical, chemical, or mechanical differences were observed between the 0.55, and 110 mM. The in vitro adhesion properties of the hydrogels increased significantly from 0.22 mM to 110 mM RuSPS. As the RuSPS concentration was increased, a significant increase in cell viability was observed. In particular, 110 mM RuSPS showed the greatest effect and created the most statistically significant difference.

 Materials that are responsive to visible light have been extensively used in biomedical applications, including tissue engineering. Tissue adhesives are among the most important applications of tissue engineering. In this study, different concentrations of Ruthenium Ru and sodium persulfate SPS photoinitiators 0.22, 0.55, and 110 mM were prepared. Sodium alginate Na-alginate was modified with methacrylate AlgMA to render it photoactive. Photoactive materials prepared with different ratios of photoinitiators were physically, chemically, morphologically, and mechanically tested. The results of the different analyses supported each other. RuSPS concentrations of 0.22, 0.55, and 110 mM were used to evaluate the hydrogel structures. No physical, chemical, or mechanical differences were observed between the 0.55, and 110 mM. The in vitro adhesion properties of the hydrogels increased significantly from 0.22 mM to 110 mM RuSPS. As the RuSPS concentration was increased, a significant increase in cell viability was observed. In particular, 110 mM RuSPS showed the greatest effect and created the most statistically significant difference.

Article Details

Preparation and in Vitro Adhesive Application of Visible Light-Activated Modified Sodium Alginate

Authors:

Rumeysa Tutar

Publisher:

Turkish Chemical Society

Main Topics:

Macromolecular Materials | Physical Properties of Materials | Natural Products and Bioactive Compounds | Characterisation of Biological Macromolecules

Journal:

Journal of the Turkish Chemical Society Section A: Chemistry Vol.12 Issue 2, pp.107-116

Document Type:

Article

Publication Date:

5/2025

Document Language:

English

Document ID (Org No.):

2001345110

pISSN:

2149-0120

AlgMA

Ru/SPS

Light-activation

visible light

Tissue adhesives

Issues

Article Details

Preparation and in Vitro Adhesive Application of Visible Light-Activated Modified Sodium Alginate

Authors: Rumeysa Tutar

Publisher: Turkish Chemical Society

Main Topics: Macromolecular Materials | Physical Properties of Materials | Natural Products and Bioactive Compounds | Characterisation of Biological Macromolecules

Journal: Journal of the Turkish Chemical Society Section A: Chemistry Vol.12 Issue 2, pp.107-116

Document Type: Article

Publication Date: 5/2025

Document Language: English

Document ID (Org No.): 2001345110

pISSN: 2149-0120

AlgMA

Ru/SPS

Light-activation

visible light

Tissue adhesives

Issues

Authors:

Rumeysa Tutar

Publisher:

Turkish Chemical Society

Main Topics:

Macromolecular Materials | Physical Properties of Materials | Natural Products and Bioactive Compounds | Characterisation of Biological Macromolecules

Journal:

Journal of the Turkish Chemical Society Section A: Chemistry Vol.12 Issue 2, pp.107-116

Document Type:

Article

Publication Date:

5/2025

Document Language:

English

Document ID (Org No.):

2001345110

pISSN:

2149-0120