Antipyretic, analgesic and anti-inflammatory activity of the methanol Mimosa himalayana extract

Md. Hossain; Md. Bashar; Mohammed Ibrahim; Muhammad Islam

doi:10.14419/ijm.v5i1.7331

Article Details

Antipyretic, analgesic and anti-inflammatory activity of the methanol Mimosa himalayana extract

Authors:

Md. Hossain | Md. Bashar | Mohammed Ibrahim | Muhammad Islam

Publisher:

Science Publishing Corporation

Journal:

International Journal of Medicine Vol.5 Issue 1, pp.87-89

Document Type:

Article

Publication Date:

7/2017

Document Language:

English

Document ID (Org No.):

2001388017

pISSN:

2309-1622

DOI:

10.14419/ijm.v5i1.7331

Keywords:

Medicinal Plant

Abstract:

 The aim of the study was to evaluate antipyretic, analgesic and anti-inflammatory activities of the methanol extract of Mimosa himalayana Gamble (Fabaceae) along with a preliminary phytochemical screening. The antipyretic and analgesic effects were tested in Swiss mice, while anti-inflammatory in egg albumin, taking paracetamol, diclofenac sodium and acetyl salicylic acid as standards, respectively. The results suggest that, the crude stem extract of M. himalayana revealed the presence of alkaloids, glycosides, saponins and gums. It exhibited antipyretic and analgesic activity at 200 and 400 mg/kg, while anti-inflammatory at 40, 80 and 160 Âµg/mL in the test systems. The activities were significant (p <0.05) in comparison to the negative control group with a high dose/concentration-mediated higher response manner. We suppose the alkaloids and glycosides may contribute its anti-inflammatory potential, which may link to the antipyretic and analgesic effects of the M. himalayana. In conclusion, M. himalayana may be one of the best sources of plant-based medicines, especially anti-inflammatory agents.

Article Details

Antipyretic, analgesic and anti-inflammatory activity of the methanol Mimosa himalayana extract

Authors: Md. Hossain | Md. Bashar | Mohammed Ibrahim | Muhammad Islam

Publisher: Science Publishing Corporation

Journal: International Journal of Medicine Vol.5 Issue 1, pp.87-89

Document Type: Article

Publication Date: 7/2017

Document Language: English

Document ID (Org No.): 2001388017

pISSN: 2309-1622

DOI: 10.14419/ijm.v5i1.7331

Medicinal Plant

Issues

Authors:

Md. Hossain | Md. Bashar | Mohammed Ibrahim | Muhammad Islam

Publisher:

Science Publishing Corporation

Journal:

International Journal of Medicine Vol.5 Issue 1, pp.87-89

Document Type:

Article

Publication Date:

7/2017

Document Language:

English

Document ID (Org No.):

2001388017

pISSN:

2309-1622

DOI:

10.14419/ijm.v5i1.7331