. TBARS, SH AND NITRIC OXIDE LEVELS IN MALE WORKERS WITH OCCUPATIONAL LEAD EXPOSURE

Gülsen YILMAZ; Hatice SÜRER; Elmas ÖĞÜŞ; Engin TUTKUN; Hınç YILMAZ; Fatma Meriç YILMAZ

Article Details

. TBARS, SH AND NITRIC OXIDE LEVELS IN MALE WORKERS WITH OCCUPATIONAL LEAD EXPOSURE

Authors:

Gülsen YILMAZ | Hatice SÜRER | Elmas ÖĞÜŞ | Engin TUTKUN | Hınç YILMAZ | Fatma Meriç YILMAZ

Publisher:

Engin TUTKUN

Journal:

The Turkish Journal Of Occupational / Environmental Medicine and Safety 2017 Vol.Volume 2 Issue İssue 1 (1), pp.1-208

Document Type:

Article

Publication Date:

2/2017

Document Language:

Turkish

Document ID (Org No.):

2000835394

Frequency:

Quarterly

eISSN:

2149-4711

pISSN:

2149-4711

Abstract:

 


To determine
TBARS (thiobarbituric acid reactive sobstances), SH (thiols) and NOx (Nitric
Oxide metabolites) levels as indicators of oxidative stress, to discuss the
correlation of oxidative stres with blood lead (Pb) concentrations and discuss
the interactions between NOx and oxidative stress in workers with occupational
lead exposure.

104 battery
workers with lead exposure and 50 healthy controls without a lead exposure were
included in the study.  Pb exposed
workers were divided into two subgroups according to their Pb concentration;
Group A: Pb ≤ 30 µg/dL (n= 52) and Group B: Pb > 30 µg/dL (n= 52).

TBARS levels
were significantly higher, SH levels were significantly lower in both of the
exposed groups when compared with controls. TBARS levels were found to be
significantly higher and SH levels were found to be significantly lower in
Group B when compared with Group A indicating that the oxidative stress
increases with the increasing blood lead levels. There was not a significant
difference in NOx levels. 

The results of
the study showed that the prooxidant-antioxidant balance in Pb exposure is
disturbed by inducing over-production of TBARS and depleting the antioxidant
capacity in a Pb concentration dependent manner. Oxidative stress has been
proposed to be a principle mechanism involved in Pb toxicity. 










 

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Article Details

. TBARS, SH AND NITRIC OXIDE LEVELS IN MALE WORKERS WITH OCCUPATIONAL LEAD EXPOSURE

Authors: Gülsen YILMAZ | Hatice SÜRER | Elmas ÖĞÜŞ | Engin TUTKUN | Hınç YILMAZ | Fatma Meriç YILMAZ

Publisher: Engin TUTKUN

Journal: The Turkish Journal Of Occupational / Environmental Medicine and Safety 2017 Vol.Volume 2 Issue İssue 1 (1), pp.1-208

Document Type: Article

Publication Date: 2/2017

Document Language: Turkish

Document ID (Org No.): 2000835394

Frequency: Quarterly

eISSN: 2149-4711

pISSN: 2149-4711

Issues

Authors:

Gülsen YILMAZ | Hatice SÜRER | Elmas ÖĞÜŞ | Engin TUTKUN | Hınç YILMAZ | Fatma Meriç YILMAZ

Publisher:

Engin TUTKUN

Journal:

The Turkish Journal Of Occupational / Environmental Medicine and Safety 2017 Vol.Volume 2 Issue İssue 1 (1), pp.1-208

Document Type:

Article

Publication Date:

2/2017

Document Language:

Turkish

Document ID (Org No.):

2000835394

Frequency:

Quarterly

eISSN:

2149-4711

pISSN:

2149-4711