Crohn's Disease : Pathophysiology and Management

Dima Ammar Fatahi; Abdullah Saad Al Asmari; Ghadah Abdulrahman Bukhari; Homoud Abdulaziz Alshamrani; Khalid Abdullah Hunaydi; Ahmad Mufarreh Sharahili; Tahani Khalid Alharshan; Anhar Ali Alherz

doi:10.12816/0044858

Article Details

Crohn's Disease : Pathophysiology and Management

Authors:

Dima Ammar Fatahi | Abdullah Saad Al Asmari | Ghadah Abdulrahman Bukhari | Homoud Abdulaziz Alshamrani | Khalid Abdullah Hunaydi | Ahmad Mufarreh Sharahili | Tahani Khalid Alharshan | Anhar Ali Alherz

Publisher:

Pan Arab League of Continuous Medical Education

Main Topics:

Medicine

Journal:

The Egyptian Journal of Hospital Medicine 2018 Vol.70 Issue 11, pp.2004-2007

Document Type:

Article

Publication Date:

1/2018

Document Language:

English

Document ID (Org No.):

114204

Frequency:

Quarterly

eISSN:

20907125

pISSN:

16872002

DOI:

10.12816/0044858

Descriptors:

Keywords:

Abstract:

 Background: The incidence of crohn’s disease reaches up to 20 per 100,000 people per year, with a median age of 30 years, and is higher in the developed world. Although the exact cause and pathophysiology is unknown, several environmental and genetic factors have been linked with higher risk or severity of the disease. Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1985, through February 2017. The following search terms were used: crohn’s disease, inflammatory bowel disease, genetics of crohn’s disease, diagnosis of IBD, management crohn’s disease Aim of the study: In this review, we aim to study the pathophysiology, diagnosis and management of crohn’s disease. We will pay special attention to the newer biological drugs used in management. Conclusion: Crohn’s disease is usually managed with medical treatment, although many patients will need to undergo surgery at least once. Treatment usually aims at the induction and maintenance of a remission without the excessive use and dependence of steroids. Achieving higher quality of life is the main goal of any modality of treatment.

Article Details

Crohn's Disease : Pathophysiology and Management

Authors:

Dima Ammar Fatahi | Abdullah Saad Al Asmari | Ghadah Abdulrahman Bukhari | Homoud Abdulaziz Alshamrani | Khalid Abdullah Hunaydi | Ahmad Mufarreh Sharahili | Tahani Khalid Alharshan | Anhar Ali Alherz

Publisher:

Pan Arab League of Continuous Medical Education

Main Topics:

Medicine

Journal:

The Egyptian Journal of Hospital Medicine 2018 Vol.70 Issue 11, pp.2004-2007

Document Type:

Article

Publication Date:

1/2018

Document Language:

English

Document ID (Org No.):

114204

Frequency:

Quarterly

eISSN:

20907125

pISSN:

16872002

DOI:

10.12816/0044858

Descriptors:

CROHN'S DISEASE

ENTERITIS

PATHOPHYSIOLOGY

DIAGNOSIS

THERAPY

Crohn’s Disease

Inflammatory Bowel Disease

Medical Management for Crohn’s Disease

Issues

Article Details

Authors: Dima Ammar Fatahi | Abdullah Saad Al Asmari | Ghadah Abdulrahman Bukhari | Homoud Abdulaziz Alshamrani | Khalid Abdullah Hunaydi | Ahmad Mufarreh Sharahili | Tahani Khalid Alharshan | Anhar Ali Alherz

Publisher: Pan Arab League of Continuous Medical Education

Main Topics: Medicine

Journal: The Egyptian Journal of Hospital Medicine 2018 Vol.70 Issue 11, pp.2004-2007

Document Type: Article

Publication Date: 1/2018

Document Language: English

Document ID (Org No.): 114204

Frequency: Quarterly

eISSN: 20907125

pISSN: 16872002

DOI: 10.12816/0044858

Descriptors:

Issues

Authors:

Dima Ammar Fatahi | Abdullah Saad Al Asmari | Ghadah Abdulrahman Bukhari | Homoud Abdulaziz Alshamrani | Khalid Abdullah Hunaydi | Ahmad Mufarreh Sharahili | Tahani Khalid Alharshan | Anhar Ali Alherz

Publisher:

Pan Arab League of Continuous Medical Education

Main Topics:

Medicine

Journal:

The Egyptian Journal of Hospital Medicine 2018 Vol.70 Issue 11, pp.2004-2007

Document Type:

Article

Publication Date:

1/2018

Document Language:

English

Document ID (Org No.):

114204

Frequency:

Quarterly

eISSN:

20907125

pISSN:

16872002

DOI:

10.12816/0044858