Antioxidant and diuretic effects of flower extract of Laurus nobilis

Nor El Houda Tahiri

Article Details

Antioxidant and diuretic effects of flower extract of Laurus nobilis

Authors:

Nor El Houda Tahiri

Publisher:

İzzet KARA

Main Topics:

Structural Biology

Journal:

International Journal of Secondary Metabolite Vol.10 Issue 4, pp.459-468

Document Type:

Article

Publication Date:

1/2023

Document Language:

English

Document ID (Org No.):

2001303333

pISSN:

2148-6905

Keywords:

Abstract:

 Diuretic medications are widely used and can come with negative effects. Because they are effective and have fewer adverse effects than other treatments for renal illness, medicinal plants have become increasingly important. This study aimed to investigate the antioxidant ability and the impact of Laurus nobilis extract flower on diuresis in rats. Two doses of 200 mg and 400 mg of Laurus nobilis extract were used to treat rats for thirty days. Then, we assessed all changes induced in urine and plasma parameters of rats, using furosemide as a standard drug. Further, we evaluated the total phenolic content TPC, total flavonoid content TFC, and antioxidant ability DPPH and FRAP of the tested extract. The results obtained show that the administration of a single dose of Laurus nobilis extract improved the urine flow significantly after 4 h of treatment. Similarly, both doses of the tested extract enhanced sodium, potassium, and chloride excretion without inducing hypokalemia. A similar tendency was recorded for both urine and creatinine, while the results of the furosemide group revealed a significant hypokalemia effect of the standard drug. Laurus nobilis demonstrated superior antioxidant and diuretic effects without inducing hypokalemia due to the higher content of phenolic and flavonoid content. However, more advanced studies are required to explore the constituents of Laurus nobilis extracts and essential oils, as well as to test their pertinent biological activities.

 Diuretic medications are widely used and can come with negative effects. Because they are effective and have fewer adverse effects than other treatments for renal illness, medicinal plants have become increasingly important. This study aimed to investigate the antioxidant ability and the impact of Laurus nobilis extract flower on diuresis in rats. Two doses of 200 mg and 400 mg of Laurus nobilis extract were used to treat rats for thirty days. Then, we assessed all changes induced in urine and plasma parameters of rats, using furosemide as a standard drug. Further, we evaluated the total phenolic content TPC, total flavonoid content TFC, and antioxidant ability DPPH and FRAP of the tested extract. The results obtained show that the administration of a single dose of Laurus nobilis extract improved the urine flow significantly after 4 h of treatment. Similarly, both doses of the tested extract enhanced sodium, potassium, and chloride excretion without inducing hypokalemia. A similar tendency was recorded for both urine and creatinine, while the results of the furosemide group revealed a significant hypokalemia effect of the standard drug. Laurus nobilis demonstrated superior antioxidant and diuretic effects without inducing hypokalemia due to the higher content of phenolic and flavonoid content. However, more advanced studies are required to explore the constituents of Laurus nobilis extracts and essential oils, as well as to test their pertinent biological activities.

 Diuretic medications are widely used and can come with negative effects. Because they are effective and have fewer adverse effects than other treatments for renal illness, medicinal plants have become increasingly important. This study aimed to investigate the antioxidant ability and the impact of Laurus nobilis extract flower on diuresis in rats. Two doses of 200 mg and 400 mg of Laurus nobilis extract were used to treat rats for thirty days. Then, we assessed all changes induced in urine and plasma parameters of rats, using furosemide as a standard drug. Further, we evaluated the total phenolic content TPC, total flavonoid content TFC, and antioxidant ability DPPH and FRAP of the tested extract. The results obtained show that the administration of a single dose of Laurus nobilis extract improved the urine flow significantly after 4 h of treatment. Similarly, both doses of the tested extract enhanced sodium, potassium, and chloride excretion without inducing hypokalemia. A similar tendency was recorded for both urine and creatinine, while the results of the furosemide group revealed a significant hypokalemia effect of the standard drug. Laurus nobilis demonstrated superior antioxidant and diuretic effects without inducing hypokalemia due to the higher content of phenolic and flavonoid content. However, more advanced studies are required to explore the constituents of Laurus nobilis extracts and essential oils, as well as to test their pertinent biological activities.

 Diuretic medications are widely used and can come with negative effects. Because they are effective and have fewer adverse effects than other treatments for renal illness, medicinal plants have become increasingly important. This study aimed to investigate the antioxidant ability and the impact of Laurus nobilis extract flower on diuresis in rats. Two doses of 200 mg and 400 mg of Laurus nobilis extract were used to treat rats for thirty days. Then, we assessed all changes induced in urine and plasma parameters of rats, using furosemide as a standard drug. Further, we evaluated the total phenolic content TPC, total flavonoid content TFC, and antioxidant ability DPPH and FRAP of the tested extract. The results obtained show that the administration of a single dose of Laurus nobilis extract improved the urine flow significantly after 4 h of treatment. Similarly, both doses of the tested extract enhanced sodium, potassium, and chloride excretion without inducing hypokalemia. A similar tendency was recorded for both urine and creatinine, while the results of the furosemide group revealed a significant hypokalemia effect of the standard drug. Laurus nobilis demonstrated superior antioxidant and diuretic effects without inducing hypokalemia due to the higher content of phenolic and flavonoid content. However, more advanced studies are required to explore the constituents of Laurus nobilis extracts and essential oils, as well as to test their pertinent biological activities.

Article Details

Antioxidant and diuretic effects of flower extract of Laurus nobilis

Authors:

Nor El Houda Tahiri

Publisher:

İzzet KARA

Main Topics:

Structural Biology

Journal:

International Journal of Secondary Metabolite Vol.10 Issue 4, pp.459-468

Document Type:

Article

Publication Date:

1/2023

Document Language:

English

Document ID (Org No.):

2001303333

pISSN:

2148-6905

Laurus nobilis flowers

Antioxidant activity

Diuretic effectLaurus nobilis flowers

Antioxidant activity

Diuretic effect

Issues

Article Details

Antioxidant and diuretic effects of flower extract of Laurus nobilis

Authors: Nor El Houda Tahiri

Publisher: İzzet KARA

Main Topics: Structural Biology

Journal: International Journal of Secondary Metabolite Vol.10 Issue 4, pp.459-468

Document Type: Article

Publication Date: 1/2023

Document Language: English

Document ID (Org No.): 2001303333

pISSN: 2148-6905

Laurus nobilis flowers

Antioxidant activity

Diuretic effectLaurus nobilis flowers

Antioxidant activity

Diuretic effect

Issues

Authors:

Nor El Houda Tahiri

Publisher:

İzzet KARA

Main Topics:

Structural Biology

Journal:

International Journal of Secondary Metabolite Vol.10 Issue 4, pp.459-468

Document Type:

Article

Publication Date:

1/2023

Document Language:

English

Document ID (Org No.):

2001303333

pISSN:

2148-6905