Oral lichen planus: a 4-year clinical follow-up study

Arunas RIMKEVICIUS; Jolanta ALEKSEJUNIENE; Alina PURIENE; Dmitrij SEININ; Ruta RASTENIENE

Article Details

Oral lichen planus: a 4-year clinical follow-up study

Authors:

Arunas RIMKEVICIUS | Jolanta ALEKSEJUNIENE | Alina PURIENE | Dmitrij SEININ | Ruta RASTENIENE

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2017 Vol.47 Issue 2, pp.514-522

Document Type:

Article

Publication Date:

3/2017

Document Language:

Turkish

Document ID (Org No.):

2000751433

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Abstract:

 

Background/aim: This study aimed to examine oral lichen planus (OLP) cases histopathologically and cytologically, describe different  clinical aspects of OLP manifestations, and associate different OLP clinical forms with self-reported oral health and with local and  systemic risk factors.  Materials and methods: All patients with a referral diagnosis of OLP received biopsies. The histological evaluation assessed infiltration  with lymphocytes, epithelial hyperplasia, and hyperkeratosis. Histology was used to validate the OLP diagnosis and to evaluate the  malignant transformation of OLP lesions. Clinical manifestations of OLP and potential local oral environment-related risks were  clinically assessed. Systemic risks were evaluated by a structured questionnaire.  Results: A total of 133 patients with a histologically confirmed OLP diagnosis were followed. There were more females (N = 109) than  males (N = 24) and the majority of patients were older than 50 years. The reticular form (45.1%) was the most prevalent clinical form  followed by the erosive-ulcerative form (33.8%). The histological characteristics were most pronounced in the erosive-ulcerative form.  Of the OLP cases, 2.3% had a malignant transformation.  Conclusion: Reticular and erosive-ulcerative were the most prevalent OLP forms. There were more female than male OLP patients.  Except for medication use, there were no statistically significant differences among different clinical OLP forms in either local or  systemic risk factor distributions.

Article Details

Oral lichen planus: a 4-year clinical follow-up study

Authors: Arunas RIMKEVICIUS | Jolanta ALEKSEJUNIENE | Alina PURIENE | Dmitrij SEININ | Ruta RASTENIENE

Publisher: TUBITAK

Journal: Turkish Journal of Medical Sciences 2017 Vol.47 Issue 2, pp.514-522

Document Type: Article

Publication Date: 3/2017

Document Language: Turkish

Document ID (Org No.): 2000751433

Frequency: Bimonthly

eISSN: 1303-6165

pISSN: 1300-0144

Issues

Authors:

Arunas RIMKEVICIUS | Jolanta ALEKSEJUNIENE | Alina PURIENE | Dmitrij SEININ | Ruta RASTENIENE

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2017 Vol.47 Issue 2, pp.514-522

Document Type:

Article

Publication Date:

3/2017

Document Language:

Turkish

Document ID (Org No.):

2000751433

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144