Penile Mondor's disease can be effectively treated with the use of an acetyl salicylic acid and pentoxifylline combination

Mürsel DAVARCI; Eşref Oğuz GÜVEN; Ahmet GÖKÇE; Fatih Rüştü YALÇINKAYA; Ahmet Namık KİPER; Mevlana Derya BALBAY

Article Details

Penile Mondor's disease can be effectively treated with the use of an acetyl salicylic acid and pentoxifylline combination

Authors:

Mürsel DAVARCI | Eşref Oğuz GÜVEN | Ahmet GÖKÇE | Fatih Rüştü YALÇINKAYA | Ahmet Namık KİPER | Mevlana Derya BALBAY

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2010 Vol.40 Issue 5, pp.735-738

Document Type:

Article

Publication Date:

4/2010

Document Language:

Turkish

Document ID (Org No.):

2000754953

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Keywords:

Abstract:

 

Since penile Mondor's disease is a rare condition, different treatment choices are used. Herein we recommend a new treatment strategy with acetylsalicylic acid and pentoxifylline, which was tested in 14 patients with penile Mondor's disease.  Materials and methods: Fourteen patients with the clinical presentation of penile Mondor's disease were included. Patients were given acetylsalicylic acid (ASA) 500 mg qid and pentoxifylline 600 mg bid for 14 days. Physical examinations were performed in all patients. In addition, ultrasonic examinations were done before the treatment and on days 7 and 14 of treatment to evaluate dorsal vein thrombosis.    Results: Physical examinations revealed lesions parallel to the coronal sulcus in 9 patients and in the dorsal aspect of the proximal penis in 5 patients. All patients had painful induration of the penis. On day 7, hyperechoic structures were still observed in 8 patients and no thrombus was seen in 6 patients. Ultrasonographic measurements were repeated 14 days after treatment and a hyperechoic structure was observed in 4 patients. No side effects were encountered during the follow-up period.   Conclusion: We think that the ASA and pentoxifylline protocol, which is also used for the treatment of thrombotic events in other parts of the body, helps to resolve penile Mondor's disease in a shorter time compared to previous treatment protocols. Further randomized controlled studies are needed for a definitive decision.

 

Since penile Mondor's disease is a rare condition, different treatment choices are used. Herein we recommend a new treatment strategy with acetylsalicylic acid and pentoxifylline, which was tested in 14 patients with penile Mondor's disease.  Materials and methods: Fourteen patients with the clinical presentation of penile Mondor's disease were included. Patients were given acetylsalicylic acid (ASA) 500 mg qid and pentoxifylline 600 mg bid for 14 days. Physical examinations were performed in all patients. In addition, ultrasonic examinations were done before the treatment and on days 7 and 14 of treatment to evaluate dorsal vein thrombosis.    Results: Physical examinations revealed lesions parallel to the coronal sulcus in 9 patients and in the dorsal aspect of the proximal penis in 5 patients. All patients had painful induration of the penis. On day 7, hyperechoic structures were still observed in 8 patients and no thrombus was seen in 6 patients. Ultrasonographic measurements were repeated 14 days after treatment and a hyperechoic structure was observed in 4 patients. No side effects were encountered during the follow-up period.   Conclusion: We think that the ASA and pentoxifylline protocol, which is also used for the treatment of thrombotic events in other parts of the body, helps to resolve penile Mondor's disease in a shorter time compared to previous treatment protocols. Further randomized controlled studies are needed for a definitive decision.

Article Details

Penile Mondor's disease can be effectively treated with the use of an acetyl salicylic acid and pentoxifylline combination

Authors:

Mürsel DAVARCI | Eşref Oğuz GÜVEN | Ahmet GÖKÇE | Fatih Rüştü YALÇINKAYA | Ahmet Namık KİPER | Mevlana Derya BALBAY

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2010 Vol.40 Issue 5, pp.735-738

Document Type:

Article

Publication Date:

4/2010

Document Language:

Turkish

Document ID (Org No.):

2000754953

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Key words: Mondor's disease

thrombophlebitis

dorsal vein thrombosis

penis

Issues

Article Details

Penile Mondor's disease can be effectively treated with the use of an acetyl salicylic acid and pentoxifylline combination

Authors: Mürsel DAVARCI | Eşref Oğuz GÜVEN | Ahmet GÖKÇE | Fatih Rüştü YALÇINKAYA | Ahmet Namık KİPER | Mevlana Derya BALBAY

Publisher: TUBITAK

Journal: Turkish Journal of Medical Sciences 2010 Vol.40 Issue 5, pp.735-738

Document Type: Article

Publication Date: 4/2010

Document Language: Turkish

Document ID (Org No.): 2000754953

Frequency: Bimonthly

eISSN: 1303-6165

pISSN: 1300-0144

Key words: Mondor's disease

thrombophlebitis

dorsal vein thrombosis

penis

Issues

Authors:

Mürsel DAVARCI | Eşref Oğuz GÜVEN | Ahmet GÖKÇE | Fatih Rüştü YALÇINKAYA | Ahmet Namık KİPER | Mevlana Derya BALBAY

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2010 Vol.40 Issue 5, pp.735-738

Document Type:

Article

Publication Date:

4/2010

Document Language:

Turkish

Document ID (Org No.):

2000754953

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144