Lipid profile and hs-CRP levels in patients with subclinical hypothyroidism

Parveen Sharma; Nivedita Prashar; Gopal Sharma; Hardeep Singh; Rashmi Sharma

Article Details

Lipid profile and hs-CRP levels in patients with subclinical hypothyroidism

Authors:

Parveen Sharma | Nivedita Prashar | Gopal Sharma | Hardeep Singh | Rashmi Sharma

Publisher:

Eldaghayes Publisher, Tripoli, Libya

Main Topics:

Subclinical hypothyroidism | hs-CRP | lipid profile

Journal:

International Journal of Medical Science and Public Health Vol.5 Issue 6, pp.1233-1233

Document Type:

Article

Publication Date:

3/2016

Document Language:

English

Document ID (Org No.):

2001522128

pISSN:

2320-4664

Keywords:

Abstract:

 Background: Several studies have demonstrated significantly lower HDL and higher triglycerides, and higher C-reactive protein (CRP) levels, in patients with subclinical hypothyroidism (SCH). 
 
 Objective: The aim of this study was to assess the levels of serum lipids and hs-CRP in patients with SCH and find out the correlation between levels of TSH with lipids and highly sensitive CRP (hs-CRP) in SCH. 
 
 Materials and Methods: This study comprised 150 patients and equal number of controls. Thyroid profile, lipid profile, and hs-CRP levels were performed on venous blood samples. Lipid profile was done using fully automated analyzer912 Hitachi. Thyroid profile was done by chemiluminescence method and the level of hs-CRP was measured using latex agglutination method. 
 
 Results: TSH positively and significantly correlated with total cholesterol, LDL-cholesterol, triglycerides, and VLDL-cholesterol and inversely and insignificantly correlated with HDL-cholesterol. TSH and hs-CRP levels were positively and significantly correlated in subclinical hypothyroid patients as compared with controls.
 
 Conclusion: In view of this study, SCH becomes an important entity due to possible link between it and cardiovascular risk factors especially lipid abnormalities. Also, significant association between TSH and hs-CRP is an important finding in this study.

Article Details

Lipid profile and hs-CRP levels in patients with subclinical hypothyroidism

Authors: Parveen Sharma | Nivedita Prashar | Gopal Sharma | Hardeep Singh | Rashmi Sharma

Publisher: Eldaghayes Publisher, Tripoli, Libya

Main Topics: Subclinical hypothyroidism | hs-CRP | lipid profile

Journal: International Journal of Medical Science and Public Health Vol.5 Issue 6, pp.1233-1233

Document Type: Article

Publication Date: 3/2016

Document Language: English

Document ID (Org No.): 2001522128

pISSN: 2320-4664

Subclinical hypothyroidism

hs-CRP

lipid profile

Issues

Authors:

Parveen Sharma | Nivedita Prashar | Gopal Sharma | Hardeep Singh | Rashmi Sharma

Publisher:

Eldaghayes Publisher, Tripoli, Libya

Main Topics:

Subclinical hypothyroidism | hs-CRP | lipid profile

Journal:

International Journal of Medical Science and Public Health Vol.5 Issue 6, pp.1233-1233

Document Type:

Article

Publication Date:

3/2016

Document Language:

English

Document ID (Org No.):

2001522128

pISSN:

2320-4664