Analyzing the efficacy of transforaminal lumbar interbody fusion (TLIF) surgery for degenerative spondylolisthesis based on clinical outcomes and spinopelvic metrics

Fahri Eryılmaz

Article Details

Analyzing the efficacy of transforaminal lumbar interbody fusion (TLIF) surgery for degenerative spondylolisthesis based on clinical outcomes and spinopelvic metrics

Authors:

Fahri Eryılmaz

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Beyin ve Sinir Cerrahisi (Nöroşirurji)

Journal:

Journal of Medicine and Palliative Care Vol.5 Issue 6, pp.314-319

Document Type:

Article

Publication Date:

12/2024

Document Language:

English

Document ID (Org No.):

2001334642

pISSN:

2717-7505

Keywords:

Abstract:

 Aims: Transforaminal lumbar interbody fusion TLIF is an increasingly used approach for treating degenerative spondylolisthesis, but limited data exist regarding its impact on spinopelvic alignment SA and related functional outcomes. Methods: 150 patients who underwent TLIF were enrolled and evaluated pre-operatively and post-operatively in this study. Radiographic analysis was used to measure spinopelvic parameters, including lumbar lordosis LL, pelvic tilt PT and sacral slope SS. Oswestry disability index ODI and visual analog scale VAS functional outcomes were assessed. Methods statistical analyses included paired t-tests, Pearson correlation coefficients, and multivariate regression for differences in parameters before and after surgery, associations between changes in spinopelvic parameters and functional outcomes, and predictors of greater improvement in the ODI, respectively. Results: Changes in LL, PT and SS from pre- to post-operative day 10, 30-points posterior pelvic plane re-orientation score. Functional output assessments showed improvement in mean ODI 34 to 20 and VAS 6.5 to 3.2 scores p0.001. Pre-operative ODI, post-operative change in LL, PT and SS predicted recovery above chance by multivariate regression p0.001. Conclusion: TLIF provides correction to SA and functional outcomes, supporting the importance of pre-operative assessment and targeted surgical planning to optimize quality of life at maximum value for each patient. Longer-term recovery and other pertinent outcome variables should be conducted.

 Aims: Transforaminal lumbar interbody fusion TLIF is an increasingly used approach for treating degenerative spondylolisthesis, but limited data exist regarding its impact on spinopelvic alignment SA and related functional outcomes. Methods: 150 patients who underwent TLIF were enrolled and evaluated pre-operatively and post-operatively in this study. Radiographic analysis was used to measure spinopelvic parameters, including lumbar lordosis LL, pelvic tilt PT and sacral slope SS. Oswestry disability index ODI and visual analog scale VAS functional outcomes were assessed. Methods statistical analyses included paired t-tests, Pearson correlation coefficients, and multivariate regression for differences in parameters before and after surgery, associations between changes in spinopelvic parameters and functional outcomes, and predictors of greater improvement in the ODI, respectively. Results: Changes in LL, PT and SS from pre- to post-operative day 10, 30-points posterior pelvic plane re-orientation score. Functional output assessments showed improvement in mean ODI 34 to 20 and VAS 6.5 to 3.2 scores p0.001. Pre-operative ODI, post-operative change in LL, PT and SS predicted recovery above chance by multivariate regression p0.001. Conclusion: TLIF provides correction to SA and functional outcomes, supporting the importance of pre-operative assessment and targeted surgical planning to optimize quality of life at maximum value for each patient. Longer-term recovery and other pertinent outcome variables should be conducted.

 Aims: Transforaminal lumbar interbody fusion TLIF is an increasingly used approach for treating degenerative spondylolisthesis, but limited data exist regarding its impact on spinopelvic alignment SA and related functional outcomes. Methods: 150 patients who underwent TLIF were enrolled and evaluated pre-operatively and post-operatively in this study. Radiographic analysis was used to measure spinopelvic parameters, including lumbar lordosis LL, pelvic tilt PT and sacral slope SS. Oswestry disability index ODI and visual analog scale VAS functional outcomes were assessed. Methods statistical analyses included paired t-tests, Pearson correlation coefficients, and multivariate regression for differences in parameters before and after surgery, associations between changes in spinopelvic parameters and functional outcomes, and predictors of greater improvement in the ODI, respectively. Results: Changes in LL, PT and SS from pre- to post-operative day 10, 30-points posterior pelvic plane re-orientation score. Functional output assessments showed improvement in mean ODI 34 to 20 and VAS 6.5 to 3.2 scores p0.001. Pre-operative ODI, post-operative change in LL, PT and SS predicted recovery above chance by multivariate regression p0.001. Conclusion: TLIF provides correction to SA and functional outcomes, supporting the importance of pre-operative assessment and targeted surgical planning to optimize quality of life at maximum value for each patient. Longer-term recovery and other pertinent outcome variables should be conducted.

 Giriş: Transforaminal lomber interbody füzyon TLIF dejeneratif spondilolistezis tedavisinde giderek daha fazla kullanılan bir yaklaşımdır, ancak spinopelvik dizilim ve ilgili fonksiyonel sonuçlar üzerindeki etkisine ilişkin sınırlı veri mevcuttur. Yöntem: Bu çalışmaya TLIF uygulanan 150 hasta dahil edildi ve ameliyat öncesi ve sonrası değerlendirildi. Lomber lordoz LL, pelvik tilt PT ve sakral eğim SS dahil olmak üzere spinopelvik parametreleri ölçmek için radyografik analiz kullanıldı. Oswestry Engellilik İndeksi ODI ve Görsel Analog Skala VAS fonksiyonel sonuçları değerlendirilmiştir. Yöntemler İstatistiksel analizler sırasıyla eşleştirilmiş t-testleri, Pearson korelasyon katsayıları ve ameliyat öncesi ve sonrası parametrelerdeki farklılıklar, spinopelvik parametrelerdeki değişiklikler ile fonksiyonel sonuçlar arasındaki ilişkiler ve ODIde daha fazla iyileşmenin belirleyicileri için çok değişkenli regresyonu içeriyordu. Bulgular: Ameliyat öncesinden ameliyat sonrası 10. güne kadar LL, PT ve SSdeki değişiklikler, 30 puanlık posterior pelvik düzlem yeniden oryantasyon skoru. Fonksiyonel çıktı değerlendirmeleri ortalama ODI 34ten 20ye ve VAS 6.5ten 3.2ye skorlarında iyileşme gösterdi p 0.001. Ameliyat öncesi ODI, ameliyat sonrası LL, PT ve SSdeki değişim çok değişkenli regresyon ile şansın üzerinde iyileşmeyi öngörmüştür p  0.001. Sonuç: TLIF, spinopelvik dizilimde ve fonksiyonel sonuçlarda düzeltme sağlayarak, her hasta için yaşam kalitesini maksimum değerde optimize etmek için ameliyat öncesi değerlendirmenin ve hedefe yönelik cerrahi planlamanın önemini desteklemektedir. Daha uzun dönem iyileşme ve diğer ilgili sonuç değişkenleri araştırılmalıdır.

Article Details

Analyzing the efficacy of transforaminal lumbar interbody fusion (TLIF) surgery for degenerative spondylolisthesis based on clinical outcomes and spinopelvic metrics

Authors:

Fahri Eryılmaz

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Beyin ve Sinir Cerrahisi (Nöroşirurji)

Journal:

Journal of Medicine and Palliative Care Vol.5 Issue 6, pp.314-319

Document Type:

Article

Publication Date:

12/2024

Document Language:

English

Document ID (Org No.):

2001334642

pISSN:

2717-7505

Transforaminal lumbar interbody fusion

interbody fusion

spine surgery

spondylolisthesistransforaminal lomber interbody füzyon

interbody füzyon

omurga cerrahisi

spondilolistezis

Issues

Article Details

Authors: Fahri Eryılmaz

Publisher: MediHealth Academy Yayıncılık

Main Topics: Beyin ve Sinir Cerrahisi (Nöroşirurji)

Journal: Journal of Medicine and Palliative Care Vol.5 Issue 6, pp.314-319

Document Type: Article

Publication Date: 12/2024

Document Language: English

Document ID (Org No.): 2001334642

pISSN: 2717-7505

Issues

Authors:

Fahri Eryılmaz

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Beyin ve Sinir Cerrahisi (Nöroşirurji)

Journal:

Journal of Medicine and Palliative Care Vol.5 Issue 6, pp.314-319

Document Type:

Article

Publication Date:

12/2024

Document Language:

English

Document ID (Org No.):

2001334642

pISSN:

2717-7505