Investigation of fatigue, mental well-being and tachycardia in short- and long-term metformin use

Zahide Akeren

Article Details

Investigation of fatigue, mental well-being and tachycardia in short- and long-term metformin use

Authors:

Zahide Akeren

Publisher:

Cukurova University

Main Topics:

İç Hastalıkları

Journal:

Cukurova Medical Journal Vol.50 Issue 1, pp.90-98

Document Type:

Article

Publication Date:

3/2025

Document Language:

English

Document ID (Org No.):

2001343859

pISSN:

2602-3032

Keywords:

Abstract:

 Purpose: The current study aimed compare short and long-term metformin users according to socio-demographic characteristics and to examine the relationships between fatigue, tachycardia and psychological well-being. Materials and Methods: In cross-sectional study were reached 92 patients, 46 short-term and 46 long-term metformin users. It was measured fatigue with the Functional Assessment of Chronic Illness Treatment-Fatigue Scale FACIT-F, tachycardia with saturation device, well-being with the World Health Organization Well-Being Index WHO-5. Results: For the group using short-term metformin, the mean; year of metformin use was 1.820.77 and pulse rate was 82.488.80, FACIT-F score was 20.377.25, and WHO-5 score was 15.703.23. The group using long-term metformin mean year of metformin use was 5.932.68, pulse rate was 84.579.64, FACIT-F score was 25.335.65 and WHO-5 score was 12.633.70. Well-being is negatively correlated with the year of diabetes, year of metformin use, pulse rate and fatigue. FACIT-F, metformin year and pulse rate explain a total of 41.9 of the variance in well-being. FACIT-F β-.51, t-5.82, p .000 and the year of metformin use β-.19, t-2.12, p .037 significantly decrease well-being, while pulse rate does not have a significant effect on well-being. Conclusions: Long-term use of metformin has been found cause fatigue and negative psychological well-being. Fatigue, year of metformin use and pulse rate number are important predictors of psychological well-being in Type II diabetes patients using metformin.

 Purpose: The current study aimed compare short and long-term metformin users according to socio-demographic characteristics and to examine the relationships between fatigue, tachycardia and psychological well-being. Materials and Methods: In cross-sectional study were reached 92 patients, 46 short-term and 46 long-term metformin users. It was measured fatigue with the Functional Assessment of Chronic Illness Treatment-Fatigue Scale FACIT-F, tachycardia with saturation device, well-being with the World Health Organization Well-Being Index WHO-5. Results: For the group using short-term metformin, the mean; year of metformin use was 1.820.77 and pulse rate was 82.488.80, FACIT-F score was 20.377.25, and WHO-5 score was 15.703.23. The group using long-term metformin mean year of metformin use was 5.932.68, pulse rate was 84.579.64, FACIT-F score was 25.335.65 and WHO-5 score was 12.633.70. Well-being is negatively correlated with the year of diabetes, year of metformin use, pulse rate and fatigue. FACIT-F, metformin year and pulse rate explain a total of 41.9 of the variance in well-being. FACIT-F β-.51, t-5.82, p .000 and the year of metformin use β-.19, t-2.12, p .037 significantly decrease well-being, while pulse rate does not have a significant effect on well-being. Conclusions: Long-term use of metformin has been found cause fatigue and negative psychological well-being. Fatigue, year of metformin use and pulse rate number are important predictors of psychological well-being in Type II diabetes patients using metformin.

 Purpose: The current study aimed compare short and long-term metformin users according to socio-demographic characteristics and to examine the relationships between fatigue, tachycardia and psychological well-being. Materials and Methods: In cross-sectional study were reached 92 patients, 46 short-term and 46 long-term metformin users. It was measured fatigue with the Functional Assessment of Chronic Illness Treatment-Fatigue Scale FACIT-F, tachycardia with saturation device, well-being with the World Health Organization Well-Being Index WHO-5. Results: For the group using short-term metformin, the mean; year of metformin use was 1.820.77 and pulse rate was 82.488.80, FACIT-F score was 20.377.25, and WHO-5 score was 15.703.23. The group using long-term metformin mean year of metformin use was 5.932.68, pulse rate was 84.579.64, FACIT-F score was 25.335.65 and WHO-5 score was 12.633.70. Well-being is negatively correlated with the year of diabetes, year of metformin use, pulse rate and fatigue. FACIT-F, metformin year and pulse rate explain a total of 41.9 of the variance in well-being. FACIT-F β-.51, t-5.82, p .000 and the year of metformin use β-.19, t-2.12, p .037 significantly decrease well-being, while pulse rate does not have a significant effect on well-being. Conclusions: Long-term use of metformin has been found cause fatigue and negative psychological well-being. Fatigue, year of metformin use and pulse rate number are important predictors of psychological well-being in Type II diabetes patients using metformin.

 Amaç: Çalışmada kısa ve uzun süreli metformin kullanıcılarının bazı sosyo-demografik özelliklerine göre karşılaştırılması ve yorgunluk, taşikardi ve ruhsal iyilik hali arasındaki ilişkilerin incelenmesi amaçlandı. Gereç ve Yöntem: Kesitsel tarama tasarımlı çalışmada, 46sı kısa süreli, 46sı uzun süreli metformin kullanıcısı olmak üzere 92 hastaya ulaşıldı. Yorgunluk, Kronik Hastalık Tedavi-Yorgunluk Fonksiyonel Değerlendirmesi Ölçeği FACIT-F, taşikardi saturasyon cihazı, iyilik hali Dünya Sağlık Örgütü İyilik Hali İndeksi WHO-5 ile ölçüldü. Bulgular: Kısa süreli metformin kullanan grupta ortalamalar; metformin kullanım yılı 1,820,77, nabız 82,488,80, FACIT-F skoru 20,377,25, WHO-5 skoru 15,703,23 olarak bulundu. Uzun süreli metformin kullanan grupta ortalamalar; metformin kullanım yılı 5,932,68, nabız 84,579,64, FACIT-F skoru 25,335,65, WHO-5 skoru 12,633,70 olarak bulundu. İyilik hali diyabet yılı, metformin kullanım yılı, nabız hızı ve yorgunlukla negatif korelasyon göstermektedir. FACIT-F, metformin yılı ve nabız hızı iyilik halinin toplam 41,9unu açıklıyor. FACIT-Fnin β-.51, t-5.82, p .000 ve metformin kullanım yılının β-.19, t-2.12, p .037 iyilik halini önemli ölçüde azalttığı, nabız hızının ise iyilik halinde önemli bir etkiye sahip olmadığı görüldü. Sonuç: Metforminin uzun süreli kullanımının yorgunluğa ve olumsuz psikolojik iyilik haline neden olduğu bulunmuştur. Yorgunluk, metformin kullanım yılı ve nabız sayısı metformin kullanan Tip II diyabet hastalarında ruhsal iyi oluşun önemli belirleyicileridir.

Article Details

Investigation of fatigue, mental well-being and tachycardia in short- and long-term metformin use

Authors:

Zahide Akeren

Publisher:

Cukurova University

Main Topics:

İç Hastalıkları

Journal:

Cukurova Medical Journal Vol.50 Issue 1, pp.90-98

Document Type:

Article

Publication Date:

3/2025

Document Language:

English

Document ID (Org No.):

2001343859

pISSN:

2602-3032

Metformin

Mental Well-Being

Fatigue

TachycardiaMetformin

Ruhsal Iyi Oluş

Yorgunluk

Taşikardi.

Issues

Article Details

Authors: Zahide Akeren

Publisher: Cukurova University

Main Topics: İç Hastalıkları

Journal: Cukurova Medical Journal Vol.50 Issue 1, pp.90-98

Document Type: Article

Publication Date: 3/2025

Document Language: English

Document ID (Org No.): 2001343859

pISSN: 2602-3032

Issues

Authors:

Zahide Akeren

Publisher:

Cukurova University

Main Topics:

İç Hastalıkları

Journal:

Cukurova Medical Journal Vol.50 Issue 1, pp.90-98

Document Type:

Article

Publication Date:

3/2025

Document Language:

English

Document ID (Org No.):

2001343859

pISSN:

2602-3032