The Role of Disease Activity as a Determinant of Central Sensitivity and Body Awareness in Fibromyalgia Patients: A Cross-Sectional Study

Yasemin Mirza; Adem Küçük

Article Details

The Role of Disease Activity as a Determinant of Central Sensitivity and Body Awareness in Fibromyalgia Patients: A Cross-Sectional Study

Authors:

Yasemin Mirza | Adem Küçük

Publisher:

Kirsehir Ahi Evran University

Main Topics:

Romatoloji ve Artrit

Journal:

Ahi Evran Tıp Dergisi Vol.9 Issue 1, pp.30-36

Document Type:

Article

Publication Date:

4/2025

Document Language:

English

Document ID (Org No.):

2001344993

pISSN:

2619-9203

Keywords:

Abstract:

 Purpose: The present study aimed to identify the influence of disease activity on central sensitization CS and body awareness in fibromyalgia syndrome FMS patients. Materials and Methods: Forty-five patients with FMS mean age: 45.9 6.9 years, median disease duration: 3 2-6 years were participated this cross-sectional study. Disease activity was assessed using the Fibromyalgia Impact Questionnaire FIQ and higher score was considered high disease activity. The Central Sensitization Inventory CSI was performed for central sensitivity. Body awareness levels were evaluated with the Body Awareness Questionnaire BAQ. Visual Analogue Scale VAS was used to identify pain severity. Simple linear regression analyses were used to determine which independent variables could explain disease activity. Results: The mean FIQ and BAQ were 53.4 and 90 points, respectively. The median VAS and CSI were 8 cm and 52 point, respectively. The CS is positive in 82.2 of all patients. FIQ was moderately correlated with the VAS score r0.445, R20.198, p0.002 and is highly correlated with CSI r0.539, R20.291, p0.001. There was no significant correlation between FIQ and BAQ p0.791. The results of the simple linear regression analysis presented that VAS explained 19.8 of the the disease activity. FIQ r0.445, p0.002 significantly predicted pain severity. Additionally, The CSI explained 29.1 of the disease activity and FIQ r0.539, p0.001 significantly predicted CS. Conclusion: High disease activity negatively impacts CS and body awareness in FMS patients. Clinicians should consider a multimodal biopsychosocial perspective in addition to routine treatments in the management of patients with high disease activity.

 Purpose: The present study aimed to identify the influence of disease activity on central sensitization CS and body awareness in fibromyalgia syndrome FMS patients. Materials and Methods: Forty-five patients with FMS mean age: 45.9 6.9 years, median disease duration: 3 2-6 years were participated this cross-sectional study. Disease activity was assessed using the Fibromyalgia Impact Questionnaire FIQ and higher score was considered high disease activity. The Central Sensitization Inventory CSI was performed for central sensitivity. Body awareness levels were evaluated with the Body Awareness Questionnaire BAQ. Visual Analogue Scale VAS was used to identify pain severity. Simple linear regression analyses were used to determine which independent variables could explain disease activity. Results: The mean FIQ and BAQ were 53.4 and 90 points, respectively. The median VAS and CSI were 8 cm and 52 point, respectively. The CS is positive in 82.2 of all patients. FIQ was moderately correlated with the VAS score r0.445, R20.198, p0.002 and is highly correlated with CSI r0.539, R20.291, p0.001. There was no significant correlation between FIQ and BAQ p0.791. The results of the simple linear regression analysis presented that VAS explained 19.8 of the the disease activity. FIQ r0.445, p0.002 significantly predicted pain severity. Additionally, The CSI explained 29.1 of the disease activity and FIQ r0.539, p0.001 significantly predicted CS. Conclusion: High disease activity negatively impacts CS and body awareness in FMS patients. Clinicians should consider a multimodal biopsychosocial perspective in addition to routine treatments in the management of patients with high disease activity.

 Purpose: The present study aimed to identify the influence of disease activity on central sensitization CS and body awareness in fibromyalgia syndrome FMS patients. Materials and Methods: Forty-five patients with FMS mean age: 45.9 6.9 years, median disease duration: 3 2-6 years were participated this cross-sectional study. Disease activity was assessed using the Fibromyalgia Impact Questionnaire FIQ and higher score was considered high disease activity. The Central Sensitization Inventory CSI was performed for central sensitivity. Body awareness levels were evaluated with the Body Awareness Questionnaire BAQ. Visual Analogue Scale VAS was used to identify pain severity. Simple linear regression analyses were used to determine which independent variables could explain disease activity. Results: The mean FIQ and BAQ were 53.4 and 90 points, respectively. The median VAS and CSI were 8 cm and 52 point, respectively. The CS is positive in 82.2 of all patients. FIQ was moderately correlated with the VAS score r0.445, R20.198, p0.002 and is highly correlated with CSI r0.539, R20.291, p0.001. There was no significant correlation between FIQ and BAQ p0.791. The results of the simple linear regression analysis presented that VAS explained 19.8 of the the disease activity. FIQ r0.445, p0.002 significantly predicted pain severity. Additionally, The CSI explained 29.1 of the disease activity and FIQ r0.539, p0.001 significantly predicted CS. Conclusion: High disease activity negatively impacts CS and body awareness in FMS patients. Clinicians should consider a multimodal biopsychosocial perspective in addition to routine treatments in the management of patients with high disease activity.

 Amaç: Bu çalışmanın amacı fibromiyalji sendromu FMS hastalarında hastalık aktivitesinin santral sensitizasyon ve vücut farkındalığı üzerine etkisini belirlemektir. Araçlar ve Yöntem: Bu kesitsel çalışmaya FMSli 45 hasta ortalama yaş: 45.9 6.9 yıl, ortanca hastalık süresi: 3 2-6 yıl katıldı. Hastalık aktivitesi, Fibromiyalji Etki Anketi FEA kullanılarak değerlendirildi ve daha yüksek puan yüksek hastalık aktivitesi olarak kabul edildi. Santral sensitizasyonu değerlendirmek için Santral Sensitizasyon Ölçeği SSÖ uygulandı. Vücut farkındalığı seviyeleri Vücut Farkındalığı Anketi VFA ile değerlendirildi. Ağrı şiddetini belirlemek için Görsel Analog Skala GAS kullanıldı. Hastalık aktivitesini hangi bağımsız değişkenin açıklayabileceğini araştırmak için basit doğrusal regresyon analizleri kullanıldı. Bulgular: Ortalama FEA ve VFA puanları sırasıyla 53.4 ve 90 dı. Ortanca GAS ve SSÖ puanları sırasıyla 8 ve 52 idi. Tüm hastaların 82.2sinde santral sensitizasyon pozitifti. FEA, GAS skoruyla orta düzeyde ilişkiliydi r0.445, R20.198, p0.002 ve SSÖ ile yüksek düzeyde ilişkiliydi r0.539, R20.291, p0.001. FEA ve VFA arasında ise anlamlı bir korelasyon saptanmadı p0.791. Basit doğrusal regresyon analizinin sonuçları, GASın hastalık aktivitesinin 19.8ini açıkladığını gösterdi. FEA r0.445, p0.002 ağrı şiddetini anlamlı şekilde tahmin etti. Ayrıca SSÖ hastalık aktivitesinin 29.1ini açıklarken, FEA r0.539, p0.001 santral sensitizasyonu anlamlı şekilde öngörüldü. Sonuç: Yüksek hastalık aktivitesi FMSli hastalarda santral sensitizasyon ve vücut farkındalığını olumsuz bir şekilde etkilemektedir. Klinisyenler yüksek hastalık aktivitesi olan hastaların yönetiminde rutin tedavilere ek olarak multimodal biyopsikososyal bakış açısını da göz önünde bulundurmalıdır.

Article Details

The Role of Disease Activity as a Determinant of Central Sensitivity and Body Awareness in Fibromyalgia Patients: A Cross-Sectional Study

Authors:

Yasemin Mirza | Adem Küçük

Publisher:

Kirsehir Ahi Evran University

Main Topics:

Romatoloji ve Artrit

Journal:

Ahi Evran Tıp Dergisi Vol.9 Issue 1, pp.30-36

Document Type:

Article

Publication Date:

4/2025

Document Language:

English

Document ID (Org No.):

2001344993

pISSN:

2619-9203

body awareness

central sensitization

fibromyalgia syndrome

disease activitybeden farkındalığı

fibromiyalji sendromu

hastalık aktivitesi

santral sensitizasyon

Issues

Article Details

Authors: Yasemin Mirza | Adem Küçük

Publisher: Kirsehir Ahi Evran University

Main Topics: Romatoloji ve Artrit

Journal: Ahi Evran Tıp Dergisi Vol.9 Issue 1, pp.30-36

Document Type: Article

Publication Date: 4/2025

Document Language: English

Document ID (Org No.): 2001344993

pISSN: 2619-9203

Issues

Authors:

Yasemin Mirza | Adem Küçük

Publisher:

Kirsehir Ahi Evran University

Main Topics:

Romatoloji ve Artrit

Journal:

Ahi Evran Tıp Dergisi Vol.9 Issue 1, pp.30-36

Document Type:

Article

Publication Date:

4/2025

Document Language:

English

Document ID (Org No.):

2001344993

pISSN:

2619-9203