Unrevealing of the Effect of Olfactory Bulb Lesion on Histomorphological  Changes in Sublingual Glands: An Experimental Study

Mehmetnuri KOÇAK; Mehmet Dumlu AYDIN; Zülküf KAYA; Erdem KARADENİZ; Atıf BAYRAMOĞLU; Ali AHISKALIOĞLU; Nazan AYDIN; Tuba DEMİRCİ

Article Details

Unrevealing of the Effect of Olfactory Bulb Lesion on Histomorphological Changes in Sublingual Glands: An Experimental Study

Authors:

Mehmetnuri KOÇAK | Mehmet Dumlu AYDIN | Zülküf KAYA | Erdem KARADENİZ | Atıf BAYRAMOĞLU | Ali AHISKALIOĞLU | Nazan AYDIN | Tuba DEMİRCİ

Publisher:

Muhammet Kaan YEŞİLYURT

Main Topics:

Applied physics

Journal:

International Journal of Innovative Research and Reviews 2019 Vol.3 Issue 2, pp.23-28

Document Type:

Article

Publication Date:

12/2019

Document Language:

English

Document ID (Org No.):

2000466555

Frequency:

Bi-Annual

eISSN:

2636-8919

Abstract:

 

This study was performed to examine basic neuropathological mechanisms of undeterminedeffects of olfactory bulb lesion in sublingual glands. Twenty-six adult rats were randomizedin three groups as control group (Group I, n=8), Sham group (Group II, n=7) and olfactorybulb lesion (OBL) group (Group III, n=11), and they all observed for the duration of eightweeks and finally euthanized. The olfactory bulbs of rat brains and sublingual glands (SLG),were extracted bilaterally. Samplings stained with hematoxylin/eosin and TUNEL stains toassess the stereogical olfactory bulbs volume loss degrees, and follicular volume values(FVV) of SLG per cubic centimeters. The estimated mean volumes of olfactory bulbs wereas 4.87±0.33/mm3 in group I, 4.32±0.43/mm3 in group II, and 2.12±0.19/mm3 in group III(p<0.0001 and p<0.0005; in Group III vs. I, Group III vs. II, respectively). The mean volumesof FVV and degenerated neuron density of SLG were 215±56×106µm3/cm3 and 13±3/mm3in Group I, 193 ± 44×106µm3/cm3 and 62±11/mm3 in Group II (p<0.005), 134±27×106µm3/cm3 and 346±83/mm3 in Group III (p<0.0001 and p<0.0005; in Group III vs. I, GroupIII vs. II, respectively). This study suggests that OBL may be responsible for sublingual glanddegeneration, which has not been stated so far.

Article Details

Unrevealing of the Effect of Olfactory Bulb Lesion on Histomorphological Changes in Sublingual Glands: An Experimental Study

Authors: Mehmetnuri KOÇAK | Mehmet Dumlu AYDIN | Zülküf KAYA | Erdem KARADENİZ | Atıf BAYRAMOĞLU | Ali AHISKALIOĞLU | Nazan AYDIN | Tuba DEMİRCİ

Publisher: Muhammet Kaan YEŞİLYURT

Main Topics: Applied physics

Journal: International Journal of Innovative Research and Reviews 2019 Vol.3 Issue 2, pp.23-28

Document Type: Article

Publication Date: 12/2019

Document Language: English

Document ID (Org No.): 2000466555

Frequency: Bi-Annual

eISSN: 2636-8919

Issues

Authors:

Mehmetnuri KOÇAK | Mehmet Dumlu AYDIN | Zülküf KAYA | Erdem KARADENİZ | Atıf BAYRAMOĞLU | Ali AHISKALIOĞLU | Nazan AYDIN | Tuba DEMİRCİ

Publisher:

Muhammet Kaan YEŞİLYURT

Main Topics:

Applied physics

Journal:

International Journal of Innovative Research and Reviews 2019 Vol.3 Issue 2, pp.23-28

Document Type:

Article

Publication Date:

12/2019

Document Language:

English

Document ID (Org No.):

2000466555

Frequency:

Bi-Annual

eISSN:

2636-8919