The Association between Lymphovascular Invasion and Other Prognostic Indicators in Operable Breast Cancer : Experience at King Hussein Medical Center

Ahlam A. Awamleh; Hussein Husban; Khaled Abu Rumman; Anas Al Rabadi; Saleh Habahbeh

doi:10.12816/0032195

Article Details

The Association between Lymphovascular Invasion and Other Prognostic Indicators in Operable Breast Cancer : Experience at King Hussein Medical Center

Authors:

Ahlam A. Awamleh | Hussein Husban | Khaled Abu Rumman | Anas Al Rabadi | Saleh Habahbeh

Publisher:

Jordanian Medical services - Jordanian Armed Forces

Main Topics:

Medicine

Journal:

Journal of the Royal Medical Services 2016 Vol.23 Issue 4, pp.11-16

Document Type:

Article

Publication Date:

12/2016

Document Language:

English

Document ID (Org No.):

95182

Frequency:

Quarterly

eISSN:

20788711

pISSN:

20788703

DOI:

10.12816/0032195

Descriptors:

Keywords:

Abstract:

 Objective: To evaluate the association between lymphovascular invasion (LVI) and different clinicopathologic features of invasive breast cancer.
Methods: Clinicopathologic and demographic data from a cohort of 298 patients, who were referred to surgery clinics at King Hussein Medical Center (KHMC) between 2007 and 2014, were retrieved and analyzed.
Results: The average age of the cohort under investigation was 51.2 years with most of the patients having invasive breast carcinoma. Lymphovascular invasion was detected in 53% of the patients. Patients with lymphovascular invasion were more likely to have larger tumors (4.2 vs. 3.3cm p=0.02). Additionally, they were more likely to have progesterone negative (p=0.032), and Her2 positive tumors (p=0.003). Patients with negative Lymphovascular were more likely to have negative perineural invasion (p=0.0001).
Conclusion: Lymphovascular invasion was associated with larger tumors, Progesterone negativity and Her-2 positivity. Lymphovascular invasion should be incorporated in tumor classification and treatment modality selection.

Article Details

The Association between Lymphovascular Invasion and Other Prognostic Indicators in Operable Breast Cancer : Experience at King Hussein Medical Center

Authors:

Ahlam A. Awamleh | Hussein Husban | Khaled Abu Rumman | Anas Al Rabadi | Saleh Habahbeh

Publisher:

Jordanian Medical services - Jordanian Armed Forces

Main Topics:

Medicine

Journal:

Journal of the Royal Medical Services 2016 Vol.23 Issue 4, pp.11-16

Document Type:

Article

Publication Date:

12/2016

Document Language:

English

Document ID (Org No.):

95182

Frequency:

Quarterly

eISSN:

20788711

pISSN:

20788703

DOI:

10.12816/0032195

Descriptors:

LYMPHOCYTES

BREAST CANCER

HORMONE RECEPTORS

BLOOD VESSELS

PROGESTERONE

NEOPLASMS

Hormone Receptor and Her-2 Status

Invasive Breast Cancer

King Hussein Medical Center

Lymphovascular Invasion

Prognostic Marker

Issues

Article Details

Authors: Ahlam A. Awamleh | Hussein Husban | Khaled Abu Rumman | Anas Al Rabadi | Saleh Habahbeh

Publisher: Jordanian Medical services - Jordanian Armed Forces

Main Topics: Medicine

Journal: Journal of the Royal Medical Services 2016 Vol.23 Issue 4, pp.11-16

Document Type: Article

Publication Date: 12/2016

Document Language: English

Document ID (Org No.): 95182

Frequency: Quarterly

eISSN: 20788711

pISSN: 20788703

DOI: 10.12816/0032195

Descriptors:

Issues

Authors:

Ahlam A. Awamleh | Hussein Husban | Khaled Abu Rumman | Anas Al Rabadi | Saleh Habahbeh

Publisher:

Jordanian Medical services - Jordanian Armed Forces

Main Topics:

Medicine

Journal:

Journal of the Royal Medical Services 2016 Vol.23 Issue 4, pp.11-16

Document Type:

Article

Publication Date:

12/2016

Document Language:

English

Document ID (Org No.):

95182

Frequency:

Quarterly

eISSN:

20788711

pISSN:

20788703

DOI:

10.12816/0032195