Evaluating the Triglyceride–Glucose Index as an Early Screening Marker for Gestational Diabetes Mellitus

Amal Muner Mubarak; Esraa Jalil; Basim M. Ali

Article Details

Evaluating the Triglyceride–Glucose Index as an Early Screening Marker for Gestational Diabetes Mellitus

Authors:

Amal Muner Mubarak | Esraa Jalil | Basim M. Ali

Publisher:

University of Kirkuk

Journal:

Kirkuk Journal of Medical Sciences Vol.14 Issue 1, pp.10-15

Document Type:

Article

Publication Date:

1/2026

Document Language:

English

Document ID (Org No.):

2001930618

pISSN:

2790-0207

Keywords:

Abstract:

 Background: Gestational diabetes mellitus (GDM) is a significant risk factor for adverse short- and long-term health outcomes for both the mother and infant. Although the oral glucose tolerance test (OGTT) is the gold standard for diagnosing GDM, its reproducibility remains debated. This study assessed the predictive accuracy of the triglyceride–glucose (TyG) index as an early biomarker for GDM.Methods: This prospective study was conducted at Al-Zahraa Teaching Hospital, Iraq, and included 150 singleton pregnant women at 7–14 weeks of gestation. Demographic and clinical data were collected. Maternal fasting blood tests were obtained for a lipid profile, fasting blood glucose, and HbA1c, and the TyG index was calculated. Predictive performance was evaluated using logistic regression and receiver operating characteristic (ROC) analysis.Results: The TyG index was positively associated with incident GDM (OR = 3.45, 95% CI: 2.22–5.36; p < 0.001). ROC analysis showed an area under the curve (AUC) of 0.89, with a cut-off value of 8.5 yielding 85.0% sensitivity and 78.0% specificity.Conclusion: An increased TyG index was significantly associated with the occurrence of GDM and may serve as an inexpensive tool for early screening.

Article Details

Evaluating the Triglyceride–Glucose Index as an Early Screening Marker for Gestational Diabetes Mellitus

Authors:

Amal Muner Mubarak | Esraa Jalil | Basim M. Ali

Publisher:

University of Kirkuk

Journal:

Kirkuk Journal of Medical Sciences Vol.14 Issue 1, pp.10-15

Document Type:

Article

Publication Date:

1/2026

Document Language:

English

Document ID (Org No.):

2001930618

pISSN:

2790-0207

gestational diabetes mellitus

Triglyceride--glucose index

insulin resistance

Pregnancy

Biomarkers

Issues

Article Details

Evaluating the Triglyceride–Glucose Index as an Early Screening Marker for Gestational Diabetes Mellitus

Authors: Amal Muner Mubarak | Esraa Jalil | Basim M. Ali

Publisher: University of Kirkuk

Journal: Kirkuk Journal of Medical Sciences Vol.14 Issue 1, pp.10-15

Document Type: Article

Publication Date: 1/2026

Document Language: English

Document ID (Org No.): 2001930618

pISSN: 2790-0207

gestational diabetes mellitus

Triglyceride--glucose index

insulin resistance

Pregnancy

Biomarkers

Issues

Authors:

Amal Muner Mubarak | Esraa Jalil | Basim M. Ali

Publisher:

University of Kirkuk

Journal:

Kirkuk Journal of Medical Sciences Vol.14 Issue 1, pp.10-15

Document Type:

Article

Publication Date:

1/2026

Document Language:

English

Document ID (Org No.):

2001930618

pISSN:

2790-0207