An old friend: uric acid and its association with fractional flow reserve

Salih TOPAL; Burak SEZENÖZ; Mustafa CANDEMİR; Eser AÇIKGÖZ; Sadik Kadri AÇIKGÖZ; Nuri Bülent BOYACI

Article Details

An old friend: uric acid and its association with fractional flow reserve

Authors:

Salih TOPAL | Burak SEZENÖZ | Mustafa CANDEMİR | Eser AÇIKGÖZ | Sadik Kadri AÇIKGÖZ | Nuri Bülent BOYACI

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 6, pp.1614-1619

Document Type:

Article

Publication Date:

11/2019

Document Language:

English

Document ID (Org No.):

2000749747

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Abstract:

 

Background/aim: The aim of this study was to investigate the importance of preprocedural uric acid (UA) level in predicting fractional flow  reserve  (FFR)  results  of  intermediate  coronary  lesions  in  patients  with  stable  coronary  artery  disease  undergoing  coronary  angiography.Materials and methods: We retrospectively analyzed 293 patients who underwent FFR measurement to determine the significance of intermediate coronary stenosis detected by conventional coronary angiography. Patients were divided into 2 groups: Group 1 (n = 127) included patients with FFR of 0.80 (hemodynamically nonsignificant lesions). Uric acid levels were assessed in both groups with the enzymatic colorimetric method by clinical chemistry autoanalyzer.Results: The  mean  UA  level  was  significantly  higher  in  patients  whose  FFR  indicated  hemodynamically  significant  coronary  lesions  (UA: 5.43 ± 1.29 mg/dL in Group 1 vs. 4.51 ± 1.34 mg/dL in Group 2, P < 0.001).Conclusion: Elevated UA levels are associated with hemodynamically significant coronary lesions measured with FFR. Uric acid may be used as a predictor of hemodynamically compromised coronary lesions before FFR procedures.

Article Details

An old friend: uric acid and its association with fractional flow reserve

Authors: Salih TOPAL | Burak SEZENÖZ | Mustafa CANDEMİR | Eser AÇIKGÖZ | Sadik Kadri AÇIKGÖZ | Nuri Bülent BOYACI

Publisher: TUBITAK

Journal: Turkish Journal of Medical Sciences 2019 Vol.49 Issue 6, pp.1614-1619

Document Type: Article

Publication Date: 11/2019

Document Language: English

Document ID (Org No.): 2000749747

Frequency: Bimonthly

eISSN: 1303-6165

pISSN: 1300-0144

Issues

Authors:

Salih TOPAL | Burak SEZENÖZ | Mustafa CANDEMİR | Eser AÇIKGÖZ | Sadik Kadri AÇIKGÖZ | Nuri Bülent BOYACI

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 6, pp.1614-1619

Document Type:

Article

Publication Date:

11/2019

Document Language:

English

Document ID (Org No.):

2000749747

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144