G-6-Pd Çorum: A New Variant of Glucose -6- Phosphate Dehydrogenase

M. Sezai Kus

Article Details

G-6-Pd Çorum: A New Variant of Glucose -6- Phosphate Dehydrogenase

Authors:

M. Sezai Kus

Publisher:

Islamic World Academy of Sciences (IAS)

Journal:

Medical Journal of Islamic World Academy of Sciences Vol.2 Issue 1, pp.31-33

Document Type:

Article

Publication Date:

1/1989

Document Language:

English

Document ID (Org No.):

2001937137

pISSN:

2415-1300

Keywords:

Abstract:

 A new variant of glucose-6-phosphate dehydrogenase (G-6-PD) is reported. Severe enzyme deficiency (1% of normal) was found in a 16-year-old Turkish school boy. This enzyme deficiency was associated with chronic haemolytic anaemia. The partially purified enzyme had a slow electrophoretic mobility in both polyacrylamide slab gel and cellulose acetate strip system, normal Km for G-6-P, decreased Km for NADP+, normal heat stability, biphasic pH curve and slightly increased utilization of 2-deoxy glucose-6-P, galactose-6-p, and deamino-NADP+. The utilization of NAD+ by the variant enzyme was increased sixfold. The variant is named G-6-PD Çorum, after the place of origin.

Article Details

G-6-Pd Çorum: A New Variant of Glucose -6- Phosphate Dehydrogenase

Authors:

M. Sezai Kus

Publisher:

Islamic World Academy of Sciences (IAS)

Journal:

Medical Journal of Islamic World Academy of Sciences Vol.2 Issue 1, pp.31-33

Document Type:

Article

Publication Date:

1/1989

Document Language:

English

Document ID (Org No.):

2001937137

pISSN:

2415-1300

Glucose-6-phosphate dehydrogenase

Glucose-6-phosphate dehydrogenase deficiency

Glucose-6-phosphate dehydrogenase variant

Haemolytic anaemia

Issues

Article Details

G-6-Pd Çorum: A New Variant of Glucose -6- Phosphate Dehydrogenase

Authors: M. Sezai Kus

Publisher: Islamic World Academy of Sciences (IAS)

Journal: Medical Journal of Islamic World Academy of Sciences Vol.2 Issue 1, pp.31-33

Document Type: Article

Publication Date: 1/1989

Document Language: English

Document ID (Org No.): 2001937137

pISSN: 2415-1300

Glucose-6-phosphate dehydrogenase

Glucose-6-phosphate dehydrogenase deficiency

Glucose-6-phosphate dehydrogenase variant

Haemolytic anaemia

Issues

Authors:

M. Sezai Kus

Publisher:

Islamic World Academy of Sciences (IAS)

Journal:

Medical Journal of Islamic World Academy of Sciences Vol.2 Issue 1, pp.31-33

Document Type:

Article

Publication Date:

1/1989

Document Language:

English

Document ID (Org No.):

2001937137

pISSN:

2415-1300