Correlation of Measurable Body Fat and Muscle Composition Parameters and Visceral Adipose Tissue on Computed Tomography with COVID-19 Severity

Duygu İmre Yetkin; Yeliz Çiçek; Erkan Büyükdemirci

Article Details

Correlation of Measurable Body Fat and Muscle Composition Parameters and Visceral Adipose Tissue on Computed Tomography with COVID-19 Severity

Authors:

Duygu İmre Yetkin | Yeliz Çiçek | Erkan Büyükdemirci

Publisher:

Selcuk University

Main Topics:

Klinik Tıp Bilimleri

Journal:

Genel Tıp Dergisi Vol.33 Issue 6, pp.703-710

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001307933

pISSN:

2602-3741

Keywords:

Abstract:

 BackgroundAims: Obesity increases the risk of having COVID-19. To evaluate the relationship between body fat, muscle composition, and visceral adipose tissue on computed tomography CT with COVID-19 outcome. Materials and Methods: 149 patients were included who had chest CT and a positive reverse transcriptase-polymerase chain reaction test. We measured the epicardial adipose tissue thickness EAT and liver density LD, thoracic subcutaneous adipose tissue pectoralis major TSATPMJ, abdominal subcutaneous adipose tissue psoas major muscle ASATPSM, abdominal subcutaneous adipose tissueerector spina muscle ASATESM thickness ratios from thorax CT. Lymphocyte, platelet, neutrophil count, lymphocyteneutrophil ratio, and CRP were recorded. Results: The mean EAT was high in the patients with a poor clinical course in severe patients: 7.062.39 mm, in critical patients: 7.892.08 mm. The mean EAT of the ICU group was 7.702.14 mm, it was 8.502.10 mm in the deceased patients. TSATPMJ was lower in deceased patients 0.900.36, p0.038. ASATPSM and ASATESM were also higher in the moderate group 2,271,60 and 0,510,25 p0.003. and p0.019 than mild one 1.591.80, and 0.400.26. There was no difference in terms of DM, malignancy, or gender. Conclusion: EAT was high in ICU-admitted and deceased patients and can be used as a predictor of poor prognosis.

 BackgroundAims: Obesity increases the risk of having COVID-19. To evaluate the relationship between body fat, muscle composition, and visceral adipose tissue on computed tomography CT with COVID-19 outcome. Materials and Methods: 149 patients were included who had chest CT and a positive reverse transcriptase-polymerase chain reaction test. We measured the epicardial adipose tissue thickness EAT and liver density LD, thoracic subcutaneous adipose tissue pectoralis major TSATPMJ, abdominal subcutaneous adipose tissue psoas major muscle ASATPSM, abdominal subcutaneous adipose tissueerector spina muscle ASATESM thickness ratios from thorax CT. Lymphocyte, platelet, neutrophil count, lymphocyteneutrophil ratio, and CRP were recorded. Results: The mean EAT was high in the patients with a poor clinical course in severe patients: 7.062.39 mm, in critical patients: 7.892.08 mm. The mean EAT of the ICU group was 7.702.14 mm, it was 8.502.10 mm in the deceased patients. TSATPMJ was lower in deceased patients 0.900.36, p0.038. ASATPSM and ASATESM were also higher in the moderate group 2,271,60 and 0,510,25 p0.003. and p0.019 than mild one 1.591.80, and 0.400.26. There was no difference in terms of DM, malignancy, or gender. Conclusion: EAT was high in ICU-admitted and deceased patients and can be used as a predictor of poor prognosis.

 BackgroundAims: Obesity increases the risk of having COVID-19. To evaluate the relationship between body fat, muscle composition, and visceral adipose tissue on computed tomography CT with COVID-19 outcome. Materials and Methods: 149 patients were included who had chest CT and a positive reverse transcriptase-polymerase chain reaction test. We measured the epicardial adipose tissue thickness EAT and liver density LD, thoracic subcutaneous adipose tissue pectoralis major TSATPMJ, abdominal subcutaneous adipose tissue psoas major muscle ASATPSM, abdominal subcutaneous adipose tissueerector spina muscle ASATESM thickness ratios from thorax CT. Lymphocyte, platelet, neutrophil count, lymphocyteneutrophil ratio, and CRP were recorded. Results: The mean EAT was high in the patients with a poor clinical course in severe patients: 7.062.39 mm, in critical patients: 7.892.08 mm. The mean EAT of the ICU group was 7.702.14 mm, it was 8.502.10 mm in the deceased patients. TSATPMJ was lower in deceased patients 0.900.36, p0.038. ASATPSM and ASATESM were also higher in the moderate group 2,271,60 and 0,510,25 p0.003. and p0.019 than mild one 1.591.80, and 0.400.26. There was no difference in terms of DM, malignancy, or gender. Conclusion: EAT was high in ICU-admitted and deceased patients and can be used as a predictor of poor prognosis.

 Arka PlanAmaçlar: Obezite, COVID-19a yakalanma riskini artırır. Amacımız bilgisayarlı tomografide BT vücut yağı, kas bileşimi ve iç organ yağ dokusu ile COVID-19 hastalık şiddetiyle arasındaki ilişkiyi değerlendirmektir. Gereç ve Yöntem: Toraks BTsi olan ve ters transkriptaz-polimeraz zincir reaksiyonu testi pozitif olan 149 hasta çalışmaya dahil edildi. Epikardiyal yağ dokusu kalınlığını EAT ve karaciğer dansitesi LD, torasik deri altı yağ dokusupektoralis majör TSATPMJ, karın deri altı yağ dokusupsoas majör kası ASATPSM, karın deri altı yağ dokusuerector spina kas ASATESM kalınlık oranlarını Toraks BTden ölçtük. Lenfosit, trombosit, nötrofil sayısı, lenfositnötrofil oranı ve CRP kaydedildi. Bulgular: Klinik gidişi kötü olan hastalarda ortalama EAT yüksekti ağır hastalarda: 7,062,39 mm, kritik hastalarda: 7,892,08 mm. Yoğun bakım grubunun ortalama EATsi 7,702,14 mm, ölen hastalarda ise 8,502,10 mm idi. Ölen hastalarda TSATPMJ daha düşüktü 0,900,36, p0,038. ASATPSM ve ASATESM de orta grupta 2,271,60 ve 0,510,25 p0,003 ve p0,019, hafif gruptan 1,591,80 ve p0,019 daha yüksekti. 0,400,26. DM, malignite ve cinsiyet açısından fark yoktu. Sonuç: YBÜye başvuran ve ölen hastalarda EAT yüksekti ve kötü prognozun bir göstergesi olarak kullanılabilir.

Article Details

Correlation of Measurable Body Fat and Muscle Composition Parameters and Visceral Adipose Tissue on Computed Tomography with COVID-19 Severity

Authors:

Duygu İmre Yetkin | Yeliz Çiçek | Erkan Büyükdemirci

Publisher:

Selcuk University

Main Topics:

Klinik Tıp Bilimleri

Journal:

Genel Tıp Dergisi Vol.33 Issue 6, pp.703-710

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001307933

pISSN:

2602-3741

Adipose tissue

computed tomography

COVID-19

epicardium.Yağ dokusu

bilgisayarlı tomografi

epikardiyum

COVID-19

Issues

Article Details

Authors: Duygu İmre Yetkin | Yeliz Çiçek | Erkan Büyükdemirci

Publisher: Selcuk University

Main Topics: Klinik Tıp Bilimleri

Journal: Genel Tıp Dergisi Vol.33 Issue 6, pp.703-710

Document Type: Article

Publication Date: 12/2023

Document Language: English

Document ID (Org No.): 2001307933

pISSN: 2602-3741

Issues

Authors:

Duygu İmre Yetkin | Yeliz Çiçek | Erkan Büyükdemirci

Publisher:

Selcuk University

Main Topics:

Klinik Tıp Bilimleri

Journal:

Genel Tıp Dergisi Vol.33 Issue 6, pp.703-710

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001307933

pISSN:

2602-3741