Smoking increases chronic postsurgical pain in patients undergoing open abdominal hysterectomy

Sümeyra Gökdemir; Senem Urfalı; Sedat Hakimoğlu; Oğuzhan Özcan; Selim Turhanoğlu; Onur Koyuncu

Article Details

Smoking increases chronic postsurgical pain in patients undergoing open abdominal hysterectomy

Authors:

Sümeyra Gökdemir | Senem Urfalı | Sedat Hakimoğlu | Oğuzhan Özcan | Selim Turhanoğlu | Onur Koyuncu

Publisher:

Hatay Mustafa Kemal University

Main Topics:

Clinical Sciences (Other)

Journal:

Interdisciplinary Medical Journal Vol.15 Issue 51, pp.1-9

Document Type:

Article

Publication Date:

4/2024

Document Language:

English

Document ID (Org No.):

2001316373

pISSN:

2980-1915

Keywords:

Abstract:

 Objectives: Smoking cause severe postoperative complications. Cotinine is the end product of nicotine in the urine. Our primary hypothesis was that women with high preoperative urinary cotinine levels have more postsurgical chronicacute pain is tested, and secondarily, that high cotinine levels are associated with more opioid consumption. Method: 158 patients undergoing open abdominal hysterectomy were divided into three groups according to the cotinine level. 1Low Cotinine group 10ngdl no exposure, 2 Intermediate Cotinine group 10-500ngdl exposure, 3 High Cotinine group 500ngdl smoker. In postoperative 3 months, postsurgical chronic pain, allodynia score, pain limiting daily activity, Brief Pain Inventory, SF 12 form, Douleur Neuropathique en 4 DN4 questions test, and Sleep interference test were assessed. Visual Analogue Scale VAS, morphine consumption, rescue analgesic consumption, and complications were recorded during postoperative 48 hours. Results: The postsurgical chronic pain scores at the three monthsp0,007, the postoperative pain scores and opioid consumption were significantly higher in the high cotinine group. High cotinine group had significantly worst HADS, SF 12 PCS, allodynia, and sleep interference test scores. Conclusion: Smoking and tobacco smoke exposure are associated with high postsurgical chronic pain, and also postoperative acute pain with more opioid consumption.

 Objectives: Smoking cause severe postoperative complications. Cotinine is the end product of nicotine in the urine. Our primary hypothesis was that women with high preoperative urinary cotinine levels have more postsurgical chronicacute pain is tested, and secondarily, that high cotinine levels are associated with more opioid consumption. Method: 158 patients undergoing open abdominal hysterectomy were divided into three groups according to the cotinine level. 1Low Cotinine group 10ngdl no exposure, 2 Intermediate Cotinine group 10-500ngdl exposure, 3 High Cotinine group 500ngdl smoker. In postoperative 3 months, postsurgical chronic pain, allodynia score, pain limiting daily activity, Brief Pain Inventory, SF 12 form, Douleur Neuropathique en 4 DN4 questions test, and Sleep interference test were assessed. Visual Analogue Scale VAS, morphine consumption, rescue analgesic consumption, and complications were recorded during postoperative 48 hours. Results: The postsurgical chronic pain scores at the three monthsp0,007, the postoperative pain scores and opioid consumption were significantly higher in the high cotinine group. High cotinine group had significantly worst HADS, SF 12 PCS, allodynia, and sleep interference test scores. Conclusion: Smoking and tobacco smoke exposure are associated with high postsurgical chronic pain, and also postoperative acute pain with more opioid consumption.

 Objectives: Smoking cause severe postoperative complications. Cotinine is the end product of nicotine in the urine. Our primary hypothesis was that women with high preoperative urinary cotinine levels have more postsurgical chronicacute pain is tested, and secondarily, that high cotinine levels are associated with more opioid consumption. Method: 158 patients undergoing open abdominal hysterectomy were divided into three groups according to the cotinine level. 1Low Cotinine group 10ngdl no exposure, 2 Intermediate Cotinine group 10-500ngdl exposure, 3 High Cotinine group 500ngdl smoker. In postoperative 3 months, postsurgical chronic pain, allodynia score, pain limiting daily activity, Brief Pain Inventory, SF 12 form, Douleur Neuropathique en 4 DN4 questions test, and Sleep interference test were assessed. Visual Analogue Scale VAS, morphine consumption, rescue analgesic consumption, and complications were recorded during postoperative 48 hours. Results: The postsurgical chronic pain scores at the three monthsp0,007, the postoperative pain scores and opioid consumption were significantly higher in the high cotinine group. High cotinine group had significantly worst HADS, SF 12 PCS, allodynia, and sleep interference test scores. Conclusion: Smoking and tobacco smoke exposure are associated with high postsurgical chronic pain, and also postoperative acute pain with more opioid consumption.

 Objectives: Smoking cause severe postoperative complications. Cotinine is the end product of nicotine in the urine. Our primary hypothesis was that women with high preoperative urinary cotinine levels have more postsurgical chronicacute pain is tested, and secondarily, that high cotinine levels are associated with more opioid consumption. Method: 158 patients undergoing open abdominal hysterectomy were divided into three groups according to the cotinine level. 1Low Cotinine group 10ngdl no exposure, 2 Intermediate Cotinine group 10-500ngdl exposure, 3 High Cotinine group 500ngdl smoker. In postoperative 3 months, postsurgical chronic pain, allodynia score, pain limiting daily activity, Brief Pain Inventory, SF 12 form, Douleur Neuropathique en 4 DN4 questions test, and Sleep interference test were assessed. Visual Analogue Scale VAS, morphine consumption, rescue analgesic consumption, and complications were recorded during postoperative 48 hours. Results: The postsurgical chronic pain scores at the three monthsp0,007, the postoperative pain scores and opioid consumption were significantly higher in the high cotinine group. High cotinine group had significantly worst HADS, SF 12 PCS, allodynia, and sleep interference test scores. Conclusion: Smoking and tobacco smoke exposure are associated with high postsurgical chronic pain, and also postoperative acute pain with more opioid consumption.

Article Details

Smoking increases chronic postsurgical pain in patients undergoing open abdominal hysterectomy

Authors:

Sümeyra Gökdemir | Senem Urfalı | Sedat Hakimoğlu | Oğuzhan Özcan | Selim Turhanoğlu | Onur Koyuncu

Publisher:

Hatay Mustafa Kemal University

Main Topics:

Clinical Sciences (Other)

Journal:

Interdisciplinary Medical Journal Vol.15 Issue 51, pp.1-9

Document Type:

Article

Publication Date:

4/2024

Document Language:

English

Document ID (Org No.):

2001316373

pISSN:

2980-1915

Cotinine

Pain

Smoke

Issues

Article Details

Smoking increases chronic postsurgical pain in patients undergoing open abdominal hysterectomy

Authors: Sümeyra Gökdemir | Senem Urfalı | Sedat Hakimoğlu | Oğuzhan Özcan | Selim Turhanoğlu | Onur Koyuncu

Publisher: Hatay Mustafa Kemal University

Main Topics: Clinical Sciences (Other)

Journal: Interdisciplinary Medical Journal Vol.15 Issue 51, pp.1-9

Document Type: Article

Publication Date: 4/2024

Document Language: English

Document ID (Org No.): 2001316373

pISSN: 2980-1915

Cotinine

Pain

Smoke

Issues

Authors:

Sümeyra Gökdemir | Senem Urfalı | Sedat Hakimoğlu | Oğuzhan Özcan | Selim Turhanoğlu | Onur Koyuncu

Publisher:

Hatay Mustafa Kemal University

Main Topics:

Clinical Sciences (Other)

Journal:

Interdisciplinary Medical Journal Vol.15 Issue 51, pp.1-9

Document Type:

Article

Publication Date:

4/2024

Document Language:

English

Document ID (Org No.):

2001316373

pISSN:

2980-1915