You have missed cancer: the unwanted plot twist of benign surgeries

İsmail Sezikli; Mahmut Arif Yüksek; Havva Hande Keser Şahin

Article Details

You have missed cancer: the unwanted plot twist of benign surgeries

Authors:

İsmail Sezikli | Mahmut Arif Yüksek | Havva Hande Keser Şahin

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Genel Cerrahi

Journal:

Anatolian Current Medical Journal Vol.7 Issue 4, pp.465-469

Document Type:

Article

Publication Date:

7/2025

Document Language:

English

Document ID (Org No.):

2001355599

pISSN:

2718-0115

Keywords:

Abstract:

 Aims: Surgical interventions for benign conditions are frequently performed in general surgery practice; however, the incidental detection of malignancies in these specimens represents a clinically significant and often overlooked issue. This study aimed to investigate the incidence, pathological characteristics, and follow-up status of incidental malignancies identified in routinely resected specimens, with a particular emphasis on the adequacy of postoperative notification and follow-up processes. Methods: A retrospective cohort study was conducted on 2.590 surgical proceduresappendectomy, cholecystectomy, abdominal wall hernia repair, hemorrhoidectomy, and pilonidal sinus excisionperformed between January 1, 2023, and January 1, 2024, at a tertiary care institution. Patients with preoperatively known or radiologically suspected malignancies were excluded. Pathological reports were reviewed for incidental malignant findings, and follow-up data were obtained via electronic health records and direct patient communication. Results: Among the reviewed cases, ten incidental malignancies 0.39 were identified: eight in appendectomy specimens, one in a cholecystectomy specimen, and one in a hernia sac. Remarkably, 30 of the affected patients were unaware of their pathological diagnosis until they were contacted by the researchers. Significant variability in specimen submission practices, especially in hernia and hemorrhoidectomy cases, may have contributed to underdiagnosis. Conclusion: Although rare, incidental malignancies carry substantial prognostic implications if left unrecognized or inadequately managed. Routine pathological evaluation of all surgical specimensregardless of presumed benignityand the implementation of automated alert systems for critical pathology results are essential for timely diagnosis, appropriate referral, and improved patient outcomes.

 Aims: Surgical interventions for benign conditions are frequently performed in general surgery practice; however, the incidental detection of malignancies in these specimens represents a clinically significant and often overlooked issue. This study aimed to investigate the incidence, pathological characteristics, and follow-up status of incidental malignancies identified in routinely resected specimens, with a particular emphasis on the adequacy of postoperative notification and follow-up processes. Methods: A retrospective cohort study was conducted on 2.590 surgical proceduresappendectomy, cholecystectomy, abdominal wall hernia repair, hemorrhoidectomy, and pilonidal sinus excisionperformed between January 1, 2023, and January 1, 2024, at a tertiary care institution. Patients with preoperatively known or radiologically suspected malignancies were excluded. Pathological reports were reviewed for incidental malignant findings, and follow-up data were obtained via electronic health records and direct patient communication. Results: Among the reviewed cases, ten incidental malignancies 0.39 were identified: eight in appendectomy specimens, one in a cholecystectomy specimen, and one in a hernia sac. Remarkably, 30 of the affected patients were unaware of their pathological diagnosis until they were contacted by the researchers. Significant variability in specimen submission practices, especially in hernia and hemorrhoidectomy cases, may have contributed to underdiagnosis. Conclusion: Although rare, incidental malignancies carry substantial prognostic implications if left unrecognized or inadequately managed. Routine pathological evaluation of all surgical specimensregardless of presumed benignityand the implementation of automated alert systems for critical pathology results are essential for timely diagnosis, appropriate referral, and improved patient outcomes.

 Aims: Surgical interventions for benign conditions are frequently performed in general surgery practice; however, the incidental detection of malignancies in these specimens represents a clinically significant and often overlooked issue. This study aimed to investigate the incidence, pathological characteristics, and follow-up status of incidental malignancies identified in routinely resected specimens, with a particular emphasis on the adequacy of postoperative notification and follow-up processes. Methods: A retrospective cohort study was conducted on 2.590 surgical proceduresappendectomy, cholecystectomy, abdominal wall hernia repair, hemorrhoidectomy, and pilonidal sinus excisionperformed between January 1, 2023, and January 1, 2024, at a tertiary care institution. Patients with preoperatively known or radiologically suspected malignancies were excluded. Pathological reports were reviewed for incidental malignant findings, and follow-up data were obtained via electronic health records and direct patient communication. Results: Among the reviewed cases, ten incidental malignancies 0.39 were identified: eight in appendectomy specimens, one in a cholecystectomy specimen, and one in a hernia sac. Remarkably, 30 of the affected patients were unaware of their pathological diagnosis until they were contacted by the researchers. Significant variability in specimen submission practices, especially in hernia and hemorrhoidectomy cases, may have contributed to underdiagnosis. Conclusion: Although rare, incidental malignancies carry substantial prognostic implications if left unrecognized or inadequately managed. Routine pathological evaluation of all surgical specimensregardless of presumed benignityand the implementation of automated alert systems for critical pathology results are essential for timely diagnosis, appropriate referral, and improved patient outcomes.

 Aims: Surgical interventions for benign conditions are frequently performed in general surgery practice; however, the incidental detection of malignancies in these specimens represents a clinically significant and often overlooked issue. This study aimed to investigate the incidence, pathological characteristics, and follow-up status of incidental malignancies identified in routinely resected specimens, with a particular emphasis on the adequacy of postoperative notification and follow-up processes. Methods: A retrospective cohort study was conducted on 2.590 surgical proceduresappendectomy, cholecystectomy, abdominal wall hernia repair, hemorrhoidectomy, and pilonidal sinus excisionperformed between January 1, 2023, and January 1, 2024, at a tertiary care institution. Patients with preoperatively known or radiologically suspected malignancies were excluded. Pathological reports were reviewed for incidental malignant findings, and follow-up data were obtained via electronic health records and direct patient communication. Results: Among the reviewed cases, ten incidental malignancies 0.39 were identified: eight in appendectomy specimens, one in a cholecystectomy specimen, and one in a hernia sac. Remarkably, 30 of the affected patients were unaware of their pathological diagnosis until they were contacted by the researchers. Significant variability in specimen submission practices, especially in hernia and hemorrhoidectomy cases, may have contributed to underdiagnosis. Conclusion: Although rare, incidental malignancies carry substantial prognostic implications if left unrecognized or inadequately managed. Routine pathological evaluation of all surgical specimensregardless of presumed benignityand the implementation of automated alert systems for critical pathology results are essential for timely diagnosis, appropriate referral, and improved patient outcomes.

Article Details

You have missed cancer: the unwanted plot twist of benign surgeries

Authors:

İsmail Sezikli | Mahmut Arif Yüksek | Havva Hande Keser Şahin

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Genel Cerrahi

Journal:

Anatolian Current Medical Journal Vol.7 Issue 4, pp.465-469

Document Type:

Article

Publication Date:

7/2025

Document Language:

English

Document ID (Org No.):

2001355599

pISSN:

2718-0115

Incidental malignancy

surgical pathology

appendectomy

cholecystectomy

follow-up systemsIncidental malignancy

surgical pathology

appendectomy

cholecystectomy

follow-up systems

Issues

Article Details

Authors: İsmail Sezikli | Mahmut Arif Yüksek | Havva Hande Keser Şahin

Publisher: MediHealth Academy Yayıncılık

Main Topics: Genel Cerrahi

Journal: Anatolian Current Medical Journal Vol.7 Issue 4, pp.465-469

Document Type: Article

Publication Date: 7/2025

Document Language: English

Document ID (Org No.): 2001355599

pISSN: 2718-0115

Issues

Authors:

İsmail Sezikli | Mahmut Arif Yüksek | Havva Hande Keser Şahin

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Genel Cerrahi

Journal:

Anatolian Current Medical Journal Vol.7 Issue 4, pp.465-469

Document Type:

Article

Publication Date:

7/2025

Document Language:

English

Document ID (Org No.):

2001355599

pISSN:

2718-0115