The pathological features of cystic fibrosis and the diagnostic techniques and treatments involved

Paphapin Pairojtanachai

Article Details

The pathological features of cystic fibrosis and the diagnostic techniques and treatments involved

Authors:

Paphapin Pairojtanachai

Publisher:

Eldaghayes Publisher, Tripoli, Libya

Main Topics:

Cystic Fibrosis | Cystic Fibrosis Transmembrane Conductance Regulator | Cystic Fibrosis Pathology | Cystic Fibrosis Diagnosis | Cystic Fibrosis Treatment

Journal:

International Journal of Medical Science and Public Health Vol.9 Issue 8, pp.452-452

Document Type:

Article

Publication Date:

8/2020

Document Language:

English

Document ID (Org No.):

2001523043

pISSN:

2320-4664

Keywords:

Abstract:

 Cystic fibrosis is a disease found predominantly in Caucasians. It is caused by an autosomal recessive mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The mutation(s) lead to defective CFTR proteins, or transmembrane cyclic adenosine monophosphate (cAMP)-dependent chloride channels found on the surface of epithelial cells. The respiratory system is most impacted by this abnormal phenotype, and lung disease can bring about the majority of the various issues that a cystic fibrosis patient has to deal with. Even so, due to the excess amount of mucus that is secreted, individuals diagnosed with cystic fibrosis experience complications in other organs as well. Today, newborn screening is widely used as a means of early diagnosis of cystic fibrosis, and there are also multiple other novel technologies that aim for accurate diagnosis and prevention of the disease. In addition, while traditional treatment programs are based on curing the symptoms that the patients exhibit, new regimens are directed at correcting the error that occurred at the molecular level. With improvements made in the medical field, cystic fibrosis patients are able to live longer and have a better quality of life. This review article serves as a compilation of the current knowledge on the causes of cystic fibrosis, the physiological processes associated with the disease, the techniques for diagnosis of the disease, and finally the recent and upcoming therapeutics for the disease.

Article Details

The pathological features of cystic fibrosis and the diagnostic techniques and treatments involved

Authors: Paphapin Pairojtanachai

Publisher: Eldaghayes Publisher, Tripoli, Libya

Main Topics: Cystic Fibrosis | Cystic Fibrosis Transmembrane Conductance Regulator | Cystic Fibrosis Pathology | Cystic Fibrosis Diagnosis | Cystic Fibrosis Treatment

Journal: International Journal of Medical Science and Public Health Vol.9 Issue 8, pp.452-452

Document Type: Article

Publication Date: 8/2020

Document Language: English

Document ID (Org No.): 2001523043

pISSN: 2320-4664

Cystic Fibrosis

Cystic Fibrosis Transmembrane Conductance Regulator

Cystic Fibrosis Pathology

Cystic Fibrosis Diagnosis

Cystic Fibrosis Treatment

Issues

Authors:

Paphapin Pairojtanachai

Publisher:

Eldaghayes Publisher, Tripoli, Libya

Main Topics:

Cystic Fibrosis | Cystic Fibrosis Transmembrane Conductance Regulator | Cystic Fibrosis Pathology | Cystic Fibrosis Diagnosis | Cystic Fibrosis Treatment

Journal:

International Journal of Medical Science and Public Health Vol.9 Issue 8, pp.452-452

Document Type:

Article

Publication Date:

8/2020

Document Language:

English

Document ID (Org No.):

2001523043

pISSN:

2320-4664